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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detinf</journal-id><journal-title-group><journal-title xml:lang="ru">ДЕТСКИЕ ИНФЕКЦИИ</journal-title><trans-title-group xml:lang="en"><trans-title>CHILDREN INFECTIONS</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-8107</issn><issn pub-type="epub">2618-8139</issn><publisher><publisher-name>Association of Pediatricians and Infection Disease doctors</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22627/2072-8107-2015-14-4-57-59</article-id><article-id custom-type="elpub" pub-id-type="custom">detinf-186</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE FROM PRACTICAL</subject></subj-group></article-categories><title-group><article-title>Гнойный менингоэнцефалит смешанной этиологии у ребенка двух лет: трудности диагностики и лечения</article-title><trans-title-group xml:lang="en"><trans-title>Purulent Meningoencephalitis Mixed Etiology in a Child Two Years Old: Problems of Diagnosis and Treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>СИМОВАНЬЯН</surname><given-names>Э. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Simovanyan</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>профессор, заведующая кафедрой детских инфекционных болезней, Ростовский государственный медицинский университет; 344022, Ростов-на-Дону, Нахичеванский 29; (863) 232-73-58</p></bio><bio xml:lang="en"><p>Professor, Head of the Department of Pediatric Infectious Diseases, Rostov on Don State Medical University; Russian Federation, 344022, Rostov-on-Don, Nakhichevansky 29; tel. (863) 232-73-58</p></bio><email xlink:type="simple">detinfrostov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ДЕНИСЕНКО</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisenko</surname><given-names>V. B.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>БОВТАЛО</surname><given-names>Л. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Bovtalo</surname><given-names>L. F.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>ТРОФИМЕНКО</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Trofimenko</surname><given-names>E. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>КРАВЦОВА</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kravtsova</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Ростовский государственный медицинский университет, Ростов-на-Дону, Российская Федерация<country>Россия</country></aff><aff xml:lang="en">Rostov-on-Don State Medical University, Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>01</day><month>12</month><year>2015</year></pub-date><volume>14</volume><issue>4</issue><fpage>57</fpage><lpage>59</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; СИМОВАНЬЯН Э.Н., ДЕНИСЕНКО В.Б., БОВТАЛО Л.Ф., ТРОФИМЕНКО Е.С., КРАВЦОВА А.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">СИМОВАНЬЯН Э.Н., ДЕНИСЕНКО В.Б., БОВТАЛО Л.Ф., ТРОФИМЕНКО Е.С., КРАВЦОВА А.В.</copyright-holder><copyright-holder xml:lang="en">Simovanyan E.N., Denisenko V.B., Bovtalo L.F., Trofimenko E.S., Kravtsova A.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://detinf.elpub.ru/jour/article/view/186">https://detinf.elpub.ru/jour/article/view/186</self-uri><abstract><p>Современной особенностью гнойных менингоэнцефалитов является частое развитие заболевания на неблагоприятном преморбидном фоне, формирование смешанной инфекции, что ведет к тяжелому затяжному течению, возникновению осложнений. На примере истории болезни ребенка двух лет с острым гнойным менингоэнцефалитом смешанной этиологии (Str. pneumoniae, H. influenzae type b), развившемся на фоне хронической герпесвирусной инфекции, резудуально-органического поражения ЦНС, представлен алгоритм диагностических и лечебных мероприятий у данной категории больных.</p></abstract><trans-abstract xml:lang="en"><p>Modern features of purulent meningoencephalitis is the frequent development of the disease at adverse premorbid background, the formation of a mixed infection, which leads to severe prolonged duration, the occurrence of complications. For example the medical history of two years old child with acute purulent meningoencephalitis mixed etiology (Str. Pneumoniae, H. influenzae type b), developed on the background of chronic herpes virus infection, rezudual-organic CNS pathology, submitted the algorithm of diagnostic and therapeutic measures in these cohort of patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бактериальный менингоэнцефалит</kwd><kwd>пневмококковая инфекция</kwd><kwd>гемофильная инфекция</kwd><kwd>герпесвирусная инфекция</kwd><kwd>дети</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bacterial purulent meningoencephalitis</kwd><kwd>pneumococcal infection</kwd><kwd>haemophilus infection</kwd><kwd>herpes virus infection</kwd><kwd>children</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Stockmann C., Ampofo K., Byington C.L. et al. ]Pneumococcal meningitis in children: epidemiology, serotypes, and outcomes from 1997—2010 in Utah] // Pediatrics. 2013. Vol.132, № 3. 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