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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detinf</journal-id><journal-title-group><journal-title xml:lang="ru">ДЕТСКИЕ ИНФЕКЦИИ</journal-title><trans-title-group xml:lang="en"><trans-title>CHILDREN INFECTIONS</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-8107</issn><issn pub-type="epub">2618-8139</issn><publisher><publisher-name>Association of Pediatricians and Infection Disease doctors</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22627/2072-8107-2016-15-3-10-15</article-id><article-id custom-type="elpub" pub-id-type="custom">detinf-239</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>ПОРАЖЕНИЯ НЕРВНОЙ СИСТЕМЫ, ВЫЗВАННЫЕ ВИРУСОМ ВАРИЦЕЛЛА-ЗОСТЕР, У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>THE LESIONS OF THE NERVOUS SYSTEM CAUSED BY THE VARICELLA-ZOSTER VIRUS IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белялетдинова</surname><given-names>И. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Belyaletdinova</surname><given-names>I. H.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белялетдинова Ильмира — младший научный сотрудник.</p></bio><bio xml:lang="en"><p>Belyaletdinova Ilmira.</p></bio><email xlink:type="simple">belyaletdinova_i@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малинникова</surname><given-names>E. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Malinnikova</surname><given-names>Yu. E.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Митрофанова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitrofanova</surname><given-names>I. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прыткова</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Prytkova</surname><given-names>M. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Институт полиомиелита и вирусных энцефалитов имени М.П. Чумакова, Москва<country>Россия</country></aff><aff xml:lang="en">Institute of Poliomyelitis and Viral Encephalitis named M.P. Chumakov, Moscow<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Российская медицинская академия последипломного образования, Москва<country>Россия</country></aff><aff xml:lang="en">Russian Medical Academy of Postgraduate Education of the Russian Federation Ministry of Health, Moscow<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Инфекционная клиническая больница №1, Москва<country>Россия</country></aff><aff xml:lang="en">Infectious Clinical Hospital №1, Moscow<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2016</year></pub-date><volume>15</volume><issue>3</issue><fpage>10</fpage><lpage>15</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Белялетдинова И.Х., Малинникова E.Ю., Митрофанова И.В., Прыткова М.И., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Белялетдинова И.Х., Малинникова E.Ю., Митрофанова И.В., Прыткова М.И.</copyright-holder><copyright-holder xml:lang="en">Belyaletdinova I.H., Malinnikova Y.E., Mitrofanova I.V., Prytkova M.I.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://detinf.elpub.ru/jour/article/view/239">https://detinf.elpub.ru/jour/article/view/239</self-uri><abstract/><trans-abstract xml:lang="en"><p>To describe the spectrum of neurological complications in children with varicella and against the background of herpes zoster. The study included children at the age of 0—16 years (n = 84), who recovered from exanthematous form of the disease not longer than 21 day before the appearance  of neurological symptoms (n = 82) or presented with herpes zoster (n = 2). Results: Clinical syndromes  included acute cerebellar ataxia (n = 37), meningoencephalitis (n = 34), meningitis (n = 7), polyradiculoneuropathy (n = 4), acute disseminated encephalomyelitis (n = 1), and ischemic stroke (n = 1). The period from varicella onset to the appearance of neurological symptoms was 6 [5;8] days. We have not lethal cases. Аcute cerebellar ataxia is most common  postvaricella complication  in children.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>вирус Варицелла-Зостер (ВВЗ)</kwd><kwd>энцефалит</kwd><kwd>неврологические осложнения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>varicella-zoster virus (VZV)</kwd><kwd>encephalitis</kwd><kwd>neurological complications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Streng A., Grote V., Carr D., Hagemann C. et al. Varicella routine vaccination and the effect son varicella epidemiology — results from the Bavarian Varicella Surveillance Project (BaVariPro), 2006—2011 // BMC Infectious Diseases. 2013, 13:303.</mixed-citation><mixed-citation xml:lang="en">Streng A., Grote V., Carr D., Hagemann C. et al. Varicella routine vaccination and the effect son varicella epidemiology — results from the Bavarian  Varicella  Surveillance  Project  (BaVariPro),  2006—2011 // BMC Infectious Diseases. 2013,  13:303.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Mérelle М.E., Visser L.F., Bokma J.A., deMelker H.E. et al. Varicella: previously healthy children sometimes develop complications // Ned Tijdschr Geneeskd. 2006. Dec 2;150(48):2625—9.</mixed-citation><mixed-citation xml:lang="en">Mérelle М.E., Visser L.F., Bokma J.A., deMelker H.E. et al. Varicella: previously healthy children sometimes develop complications // Ned Tijdschr Geneeskd. 2006. Dec 2;150(48):2625—9.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Science M. , MacGregor D., Richardson S.E., Mahant S. et al. Central nervous system complications of varicella-zoster virus // J Pediatr. 2014 Oct;165(4):779—85.</mixed-citation><mixed-citation xml:lang="en">Science M. , MacGregor D., Richardson S.E., Mahant S. et al. Central nervous system complications of varicella-zoster virus // J Pediatr. 2014 Oct;165(4):779—85.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bozzola E., Tozzi A.E., Bozzola M., Krzysztofiak A. et al. Neurological complications of varicella in childhood: case series and a systematic review of the literature // Vaccine. 2012, 30(39):5785—5790.</mixed-citation><mixed-citation xml:lang="en">Bozzola E., Tozzi A.E., Bozzola M., Krzysztofiak A. et al. Neurological complications of varicella in childhood: case series and a systematic    review    of    the   literature    //  Vaccine.    2012, 30(39):5785—5790.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Скрипченко Н.В., Иванова Г.П., Команцев В.Н., Савина М.В. Современные особенности ветряночных энцефалитов у детей // Журнал инфектологии, Том 1, № 4, 2009, С. 36—43. Skripchenko N.V., Ivanova G.P., Komantsev V.N., Savina S.V. Modern features of varicella encephalitis in children // Journal Infektologii, V. 1, № 4, 2009, Р. 36—43. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Skripchenko N.V., Ivanova G.P., Komantsev V.N., Savina S.V. Modern features of varicella encephalitis in children // Journal Infektologii, V. 1, № 4, 2009,  Р. 36—43. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Bozzola E., Bozzola M., Tozzi A. E., Calcaterra V. et al. Acute cerebellitis in varicella: a ten year case series and systematic review of the literature // Italian Journal of Pediatrics. 2014, 40:57.</mixed-citation><mixed-citation xml:lang="en">Bozzola E., Bozzola M., Tozzi A. E., Calcaterra V. et al. Acute cerebellitis in varicella: a ten year case series and systematic review of the literature // Italian Journal of Pediatrics. 2014,  40:57.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Spiegel R., Miron D., Lumelsky D., Horovitz Y. Severe meningoencephalitis due to late reactivation of Varicella-Zoster virus in an immunocompetent child // J Child Neurol. 2010. Jan;25(1):87—90.</mixed-citation><mixed-citation xml:lang="en">Spiegel R., Miron D., Lumelsky D., Horovitz Y. Severe meningoencephalitis due to late reactivation of Varicella-Zoster virus in an immunocompetent child // J Child Neurol. 2010. Jan;25(1):87—90.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Fabiano V., Dilillo D., Mauri S., Vivaldo T. et al. Herpes zoster in an immunocompetent boy following intrauterine exposure to varicellazoster virus // Cutis. 2013. Mar; 91(3):127—8, 140.</mixed-citation><mixed-citation xml:lang="en">Fabiano V., Dilillo D., Mauri S., Vivaldo T. et al. Herpes zoster in an immunocompetent boy following intrauterine exposure to varicellazoster virus // Cutis. 2013. Mar; 91(3):127—8, 140.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Paul R., Singhania P., Hashmi M., Bandyopadhyay R. et al. Post chicken pox neurological sequelae: Three distinct presentations // J Neurosci Rural Pract. 2010. Jul;1(2):92—6.</mixed-citation><mixed-citation xml:lang="en">Paul  R., Singhania  P., Hashmi  M., Bandyopadhyay  R. et al. Post chicken pox neurological sequelae: Three distinct presentations // J Neurosci Rural Pract. 2010. Jul;1(2):92—6.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Kang J.H., Sheu J.J., Lin H.C. Increased risk of Guillain-Barré Syndrome following recent herpes zoster: a population-based study across Taiwan // Clin Infect Dis. 2010. Sep 1;51(5):525—30.</mixed-citation><mixed-citation xml:lang="en">Kang J.H., Sheu J.J., Lin H.C. Increased risk of Guillain-Barré Syndrome following recent herpes zoster: a population-based study across Taiwan // Clin Infect Dis. 2010. Sep 1;51(5):525—30.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Pahud B.A., Glaser C.A., Dekker C.L., Arvin A.M. et al. Varicella zoster disease of the central nervous system: epidemiological, clinical, and laboratory features 10 years after the introduction of the varicella vaccine // J Infect Dis. 2011. Feb 1;203(3):316—23.</mixed-citation><mixed-citation xml:lang="en">Pahud B.A., Glaser C.A., Dekker C.L., Arvin A.M. et al. Varicella zoster disease of the central nervous system: epidemiological, clinical, and laboratory features 10 years after the introduction of the varicella vaccine // J Infect Dis. 2011. Feb 1;203(3):316—23.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
