<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detinf</journal-id><journal-title-group><journal-title xml:lang="ru">ДЕТСКИЕ ИНФЕКЦИИ</journal-title><trans-title-group xml:lang="en"><trans-title>CHILDREN INFECTIONS</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-8107</issn><issn pub-type="epub">2618-8139</issn><publisher><publisher-name>Association of Pediatricians and Infection Disease doctors</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22627/2072-8107-2016-15-3-50-57</article-id><article-id custom-type="elpub" pub-id-type="custom">detinf-247</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>TO HELP OF PRACTICAL PEDIATRICS</subject></subj-group></article-categories><title-group><article-title>МИКОПЛАЗМЕННАЯ ИНФЕКЦИЯ У ДЕТЕЙ: СОВРЕМЕННАЯ ДИАГНОСТИКА И ТЕРАПИЯ</article-title><trans-title-group xml:lang="en"><trans-title>MYCOPLASMA INFECTION IN CHILDREN: CURRENT DIAGNOSIS AND TREATMENT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Харламова</surname><given-names>Ф. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Harlamova</surname><given-names>F. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Харламова Флора Семеновна — доктор медицинских наук,  профессор кафедры инфекционных болезней у детей РНИМУ.</p><p>117049, Москва, 4-й Добрынинский пер., 1, МДГКБ; (499) 236-25-51, kharlamova47@bk.ru</p></bio><bio xml:lang="en"><p>Kharlamovа Flora — MD, professor of department of infectious diseases in children.</p><p>117049, Moscow, 4th Dobryninsky lane, 1.; (499) 236-25-51, kharlamova47@bk.ru</p></bio><email xlink:type="simple">kharlamova47@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шамшева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shamsheva</surname><given-names>O. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воробьева</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vorobyevа</surname><given-names>D. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanova</surname><given-names>J. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вальтц</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Valtts</surname><given-names>N. L.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisova</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Российский национальный исследовательский медицинский университет имени Н.И. Пирогова, Москва<country>Россия</country></aff><aff xml:lang="en">Russian National Research Medical University after N.I. Pirogov, Moscow<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Морозовская детская городская клиническая больница, Москва<country>Россия</country></aff><aff xml:lang="en">Morozovskaya Children's Clinical hospital, Moscow<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Многопрофильная клиника «Vessel Clinic», Москва<country>Россия</country></aff><aff xml:lang="en">Multidisciplinary Clinic «Vessel Clinic, Moscow<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>01</day><month>10</month><year>2016</year></pub-date><volume>15</volume><issue>3</issue><fpage>50</fpage><lpage>57</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Харламова Ф.С., Шамшева О.В., Воробьева Д.А., Романова Ю.В., Вальтц Н.Л., Денисова А.В., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Харламова Ф.С., Шамшева О.В., Воробьева Д.А., Романова Ю.В., Вальтц Н.Л., Денисова А.В.</copyright-holder><copyright-holder xml:lang="en">Harlamova F.S., Shamsheva O.V., Vorobyevа D.A., Romanova J.V., Valtts N.L., Denisova A.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://detinf.elpub.ru/jour/article/view/247">https://detinf.elpub.ru/jour/article/view/247</self-uri><abstract><p>Представлены  литературные  и собственные  данные (52  больных) о роли микоплазменной  инфекции в детском возрасте. Микоплазменная  инфекция сопровождается у детей длительной антигенемией, обусловливающей  рецидивы заболевания и аутоиммунизацию. Среди 52 обследованных  больных пневмония диагностирована у 17, бронхит — у 19, риносинусит — у 11, синдром Стивенса-Джонсона — у 2 детей. В половине случаев микоплазмоз протекает на фоне активной персистирующей герпесвирусной инфекции ( у 27 детей (52%). Для оптимизации этиотропной и патогенетической терапии микоплазмоза необходима коррекция  иммунных нарушений.</p></abstract><trans-abstract xml:lang="en"><p>Presents literary and own data (52 patients) on the role of mycoplasma infection. Mycoplasma infection is associated with long-term antigenemia in children, causes recurrent disease and autoimmunity. Among the 52 examined patients diagnosed with pneumonia in 17, bronchitis — from 19, rhinosinusitis  — at 11, StevensJohnson syndrome — in 2 children.  In half the cases mycoplasmosis occurs against the backdrop of persistent active herpes virus infection (in 27 children (52%). To optimize the causal and pathogenetic therapy mycoplasma requires correction of immune disorders.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>микоплазменная инфекция</kwd><kwd>дети</kwd><kwd>пневмония</kwd><kwd>синдром Стивенса-Джонсона</kwd></kwd-group><kwd-group xml:lang="en"><kwd>mycoplasma infection</kwd><kwd>children</kwd><kwd>pneumonia</kwd><kwd>Stevens-Johnson syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Прозоровский С.В., Раковская И.В., Вульфович Ю.В. Медицинская микоплазмология. — М., 1995. — 287 с. Prozorovskiy S.V., Rakovskaya I.V., Vulfovich Yu.V. [Medical mikoplazmologiya]. — M., 1995. — 287 p. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Prozorovskiy S.V., Rakovskaya I.V., Vulfovich  Yu.V. [Medical mikoplazmologiya]. — M., 1995. — 287 p. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Покровский В.И., Прозоровский С.В. Новые аспекты инфекционной пульмонологии // Эпидемиология и инфекционная патология. 1989. С. 12—13. Pokrovskiy V.I., Prozorovskiy S.V. [New aspects of infectious Pulmonology] // Epidemiology and Infectious Diseases. 1989. P. 12—13. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Pokrovskiy V.I., Prozorovskiy S.V. [New aspects of infectious Pulmonology] // Epidemiology and Infectious Diseases. 1989.  P. 12—13. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические лекции / под ред. профессора В.Н. Прилепской. 4-е изд. — М.: МЕДпресс-информ, 2005. 390 с. [Clinical lectures] / ed. prof. V.N. Prilepskaya. 4th ed. — M .: MEDpress-Inform, 2005. 390 p. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Clinical lectures]  / ed. prof. V.N. Prilepskaya.  4th  ed. —  M .: MEDpress-Inform, 2005. 390 p. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Новиков А.И., Кононов А.В., Ваганова И.Г. Инфекции, передаваемые половым путем, и экзоцервикс. — М.: Медицина, 2002. 176 с. Novikov A.I., Kononov A.V., Vaganova I.G. [Infections, sexually transmitted infections, and ekzotserviks]. — M.: Medicine, 2002. 176 p. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Novikov A.I., Kononov  A.V., Vaganova I.G. [Infections, sexually transmitted  infections,  and ekzotserviks].  —  M.: Medicine,  2002. 176 p. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Прилепская В.Н., Быковская О.В. Уреаплазменная инфекция: клиника, диагностика, лечение // Патология шейки матки. Генитальные инфекции. 2006(1):46—52. Prilepskaya V.N., Bykovskaya O.V. [Ureaplasma infection: clinical features, diagnosis, treatment] // Cervical Pathology. Genital Infection. 2006 (1): 46—52. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Prilepskaya V.N., Bykovskaya O.V. [Ureaplasma infection: clinical features, diagnosis, treatment] // Cervical Pathology. Genital Infection. 2006 (1): 46—52. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Donovan B. Sexually transmissible infections than HIV // Lancet. 2004(363):545—56.</mixed-citation><mixed-citation xml:lang="en">Donovan B. Sexually transmissible infections than HIV // Lancet. 2004(363):545—56.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Немченко О.И., Уварова Е.В. Урогенитальный микоплазмоз у девочек // Репродуктивное здоровье детей и подростков. 2005(2):3—15. Nemchenko O.I., Uvarovа E.V. [Urogenital mycoplasmosis girls] // Reproductive Health of Children and Adolescents. 2005 (2): 3—15. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Nemchenko O.I., Uvarovа E.V. [Urogenital mycoplasmosis girls] // Reproductive Health of Children and Adolescents. 2005  (2): 3—15. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Чешик С.Г., Линкова С.А., Афанасьева В.А. и др. Клинико-рентгенологическая характеристика бронхолегочного микоплазмоза у детей // Педиатрия. 1987. № 1. С. 34—39. Cheshik S.G., Linkova S.A., Afanasyevа V.A. et al. [Clinical and radiological characteristics of bronchopulmonary mycoplasmosis in infants] // Pediatrics. 987. № 1. Р. 34—39. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Cheshik S.G., Linkova S.A., Afanasyevа V.A. et al. [Clinical and radiological  characteristics  of bronchopulmonary mycoplasmosis  in infants] // Pediatrics. 987. № 1. Р. 34—39. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Самсыгина Г.А. Микоплазмоз респираторного тракта у детей и подростков // Consilium Medicum. Педиатрия (прилож.). 2009(3):78—81. Samsygina G.A. [Mycoplasmosis respiratory tract in children and adolescents] // Consilium Medicum. Pediatrics (App.). 2009 (3): 78—81. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Samsygina G.A. [Mycoplasmosis respiratory tract in children and adolescents] // Consilium Medicum. Pediatrics (App.). 2009  (3): 78—81. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bruch L.A., Jefferson R.J., Pike M.G. et al. Mycoplasma pneumoniae infection, menin goencephalitis, and hemophagocytosis // Pediatr. Neurol. 2001(25; 1):67—70.</mixed-citation><mixed-citation xml:lang="en">Bruch L.A., Jefferson R.J., Pike M.G. et al. Mycoplasma pneumoniae infection, menin goencephalitis, and hemophagocytosis // Pediatr. Neurol. 2001(25; 1):67—70.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Denny F.W., Clyde W.A., Glezen W. P. Mycoplasma pneumoniae disease: Clinical spectrum, pathophysiology, epidemiology and control // J. Infect. Dis. 1971 (123): 74.</mixed-citation><mixed-citation xml:lang="en">Denny F.W., Clyde W.A., Glezen W. P. Mycoplasma pneumoniae disease: Clinical spectrum,  pathophysiology,  epidemiology  and control // J. Infect. Dis. 1971 (123): 74.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Медицинская микробиология / Под ред. В.И. Покровского, О.К. Поздеева. — М: ГЭОТАР МЕДИЦИНА, 1999. [Medical microbiology] / ed. V.I. Pokrovskiy, O.K. Pozdeev. — M: GEOTAR MEDICINE, 1999. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Medical microbiology] / ed. V.I. Pokrovskiy, O.K. Pozdeev. — M: GEOTAR MEDICINE, 1999. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Раковская И.В. Микоплазмы и микоплазмозы человека: Руководство для врачей. — М., 1999. Rakovskaya I.V. [Mycoplasma and mycoplasmosis]: A Guide for Physicians. — M., 1999. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Rakovskaya I.V.  [Mycoplasma and mycoplasmosis]:  A Guide for Physicians. — M., 1999. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Чемоданов В.В. Новая эра — новые стандарты назначения антибиотиков // Практика педиатра. 2004, Декабрь. С.18—21. Chemodanov V.V. [A new era — new appointments standards antibiotics] // Practice Pediatrician. 2004, December. Р.18—21. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Chemodanov V.V. [A new era — new appointments standards antibiotics] // Practice Pediatrician.  2004,  December. Р.18—21. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Таточенко В.К. Антибиотики при острых респираторных заболеваниях у детей // Consilium Medicum. 2004, приложение №1. С. 3—6. Tatochenko V.K. [Antibiotics for acute respiratory illnesses in children] // Consilium Medicum. 2004, №1 (app). P. 3—6. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Tatochenko  V.K. [Antibiotics  for  acute  respiratory illnesses  in children] // Consilium Medicum. 2004,  №1 (app). P. 3—6. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Страчунский Л.С., Козлов С.Н. Макролиды в современной клинической практике. — Смоленск: Русич, 1998. — 304 с. Stratchounskiy L.S., Kozlov S.N. [Macrolides in modern clinical practice]. — Smolensk: Rusich, 1998. — 304 p. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Stratchounskiy  L.S.,  Kozlov  S.N. [Macrolides in  modern  clinical practice]. — Smolensk: Rusich, 1998. — 304 p. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Таточенко В.К. Практическая пульмонология детского возраста. — М., 2001. — 268 с. Tatochenko V.K. [Practical pediatric pulmonology]. — M., 2001. — 268 p. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Tatochenko V.K. [Practical  pediatric pulmonology]. — M., 2001. — 268 p. (In Russ.)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
