detinfДЕТСКИЕ ИНФЕКЦИИCHILDREN INFECTIONS2072-81072618-8139Association of Pediatricians and Infection Disease doctors10.22627/2072-8107-2018-17-4-43-45detinf-391Research ArticleВОПРОСЫ ТЕРАПИИPROBLEMS OF THERAPYПрименение средств растительного происхождения при ОРВИ у детейThe Use of Plant Origin Remedies in Children with ARVIhttps://orcid.org/0000-0002-6033-6695ШамшеваО. В.ShamshevaO. V.

Шамшева Ольга Васильевна, доктор медицинских наук, профессор, заведующая кафедрой инфекционных болезней у детей

Москва

Olga Shamsheva, MD, Рrofessor, head of the Department of Infectious Diseases in Children

Moscow

ch-infection@mail.ruРоссийский национальный исследовательский медицинский университет им. Н.И. Пирогова МЗ РФРоссияRussian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian FederationRussian Federation2018011220181744345Copyright © Шамшева О.В., 20182018Шамшева О.В.Shamsheva O.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://detinf.elpub.ru/jour/article/view/391

Представлен анализ научной литературы и результатов клинических исследований безопасности и эффективности применения в период респираторных инфекций компонентов растительного происхождения и продуктов пчеловодства, входящих в состав биологически активных добавок к пище — Мармелад «Прополис с травами», Леденцы для горла с мёдом и Ночной сироп алтейный с медом линии INVAR KIDS. Показано, что применение в качестве симптоматической терапии растительных средств, содержащих компоненты с установленной клинической безопасностью и доказанной эффективностью, является обоснованным для облегчения основных симптомов респираторных заболеваний у детей.

The analysis of the scientific literature and the results of clinical studies on the safety and efficacy of using for respiratory infections components of plant origin and bee products included in the composition of biologically active food supplements — «Propolis with Herbs» marmalade, throat lollipop with honey and Althaea night syrup with honey-line INVAR KIDS. It has been shown that the use of herbal remedies that contain components with established clinical safety and proven efficacy as a symptomatic therapy is reasonable for alleviating the main symptoms of respiratory diseases in children.

острые респираторные вирусные инфекции (ОРВИ)детифитопрепаратыacute respiratory viral infections (ARVI)childrenherbal remediesReferencesПриказ МЗ РФ №117 от 15 апреля 1997г. «О порядке экспертизы и гигиенической сертификации биологически активных добавок к пище. Здравоохранение, 1997; 6.Order of the Ministry of Health of the Russian Federation No. 117 of April 15, 1997. «On the order of examination and hygienic certification of biologically active food additives. Health Care, 1997; 6. (In Russ.)Weiss R.F. Lehrbuch der Phytotherapie, 7th ed. [Textbook of phytotherapy, 7th ed. Stuttgart, Hippokrates, 1991.Weiss R.F. Lehrbuch der Phytotherapie, 7th ed. [Textbook of phytotherapy, 7th ed. Stuttgart, Hippokrates, 1991.Reynolds J.E.F., ed. Fennel, fennel oil. In: Martindale — the extra pharmacopoeia, 30th ed. London, The Pharmaceutical Press, 1993.Reynolds J.E.F., ed. Fennel, fennel oil. In: Martindale — the extra pharmacopoeia, 30th ed. London, The Pharmaceutical Press, 1993.Müller-Limmroth W., Fröhlich H.H. Wirkungsnachweis einiger phytotherapeutischer Expektorantien auf den mukoziliaren Transport. Effect of various phytotherapeutic expectorants on mucociliary transport. Fortschrift für Medizin, 1980, 98:95—101.Müller-Limmroth W., Fröhlich H.H. Wirkungsnachweis einiger phytotherapeutischer Expektorantien auf den mukoziliaren Transport. Effect of various phytotherapeutic expectorants on mucociliary transport. Fortschrift für Medizin, 1980, 98:95—101.Boyd E.M., Sheppard E.P. An autumn-enhanced mucotropic action of inhaled terpenes and related volatile agents. Pharmacology, 1971, 6:65—80.Boyd E.M., Sheppard E.P. An autumn-enhanced mucotropic action of inhaled terpenes and related volatile agents. Pharmacology, 1971, 6:65—80.Van den Broucke C.O., Lemli J.A. Spasmolytic activity of the flavonoids from Thymus vulgaris. Pharmaceutisch Weekblad, scientific edition, 1983, 5:9—14.Van den Broucke C.O., Lemli J.A. Spasmolytic activity of the flavonoids from Thymus vulgaris. Pharmaceutisch Weekblad, scientific edition, 1983, 5:9—14.Freytag A. Über den Einfluß von Thymianöl, Thymol und Carvacrol auf dieFlimmerbewegung. Pflügers Archiv, European journal of physiology, 1933, 232:346— 350.Freytag A. Über den Einfluß von Thymianöl, Thymol und Carvacrol auf dieFlimmerbewegung. Pflügers Archiv, European journal of physiology, 1933, 232:346— 350.Janssen A.M., Scheffer J.J.C., Baerheim-Svendsen A. Antimicrobial activity of essential oils: A 1976—1986 literature review. Aspects of the test methods. Planta medica, 1987, 53:395—398.Janssen A.M., Scheffer J.J.C., Baerheim-Svendsen A. Antimicrobial activity of essential oils: A 1976—1986 literature review. Aspects of the test methods. Planta medica, 1987, 53:395—398.Juven B.J., Kanner J., Schved F., Weisslowicz H. Factors that interact with the antibacterial action of thyme essential oil and its active constituents. Journal of applied bacteriology, 1994, 76:626—631.Juven B.J., Kanner J., Schved F., Weisslowicz H. Factors that interact with the antibacterial action of thyme essential oil and its active constituents. Journal of applied bacteriology, 1994, 76:626—631.Farre R., Frasquet I., Sanchz A. Propolis and human health. Ars Pharmaceutica, 45:1; 21—43, 2004.Farre R., Frasquet I., Sanchz A. Propolis and human health. Ars Pharmaceutica, 45:1; 21—43, 2004.Strehl E., Volpert R., Elstner E.F. Biochemical activities of propolis extracts. III. Inhibition of dihydrofolate reductase. Z Naturforsch C, 1994; 49(1-2):39—43.Strehl E., Volpert R., Elstner E.F. Biochemical activities of propolis extracts. III. Inhibition of dihydrofolate reductase. Z Naturforsch C, 1994; 49(1-2):39—43.Wagih El-Shouny, Fouad Muagam, Zaidoon Sadik, Walaa Hamza. Antimicrobial Activity of Propolis Extract on URT Infections in Pediatric Patients Admitted to Al-Thowrah Hospital, Hodeidah City, Yemen World Journal of Medical Sciences, 2012; 7(3):172—177.Wagih El-Shouny, Fouad Muagam, Zaidoon Sadik, Walaa Hamza. Antimicrobial Activity of Propolis Extract on URT Infections in Pediatric Patients Admitted to Al-Thowrah Hospital, Hodeidah City, Yemen World Journal of Medical Sciences, 2012; 7(3):172—177.Kujumgiev A., Tsvetkova I., Serkedjieva Y., Bankova V., Christov R., Popov S. Antibacterial, antifungical and antiviral activity of propolis of different geographic origin. J Etnopharmacol, 1999; 64(3): 235—240.Kujumgiev A., Tsvetkova I., Serkedjieva Y., Bankova V., Christov R., Popov S. Antibacterial, antifungical and antiviral activity of propolis of different geographic origin. J Etnopharmacol, 1999; 64(3): 235—240.Franz G. Polysaccharides in pharmacy: current applications and future concepts. Planta Medica, 1989, 55:493—497.Franz G. Polysaccharides in pharmacy: current applications and future concepts. Planta Medica, 1989, 55:493—497.Blumenthal M. et al., eds. The complete German Commission E monographs. Austin, TX, American Botanical Council, 1998; Reynolds J.E.F, ed. Martindale, the extra pharmacopoeia, 30th ed. London, Pharmaceutical Press, 1996.Blumenthal M. et al., eds. The complete German Commission E monographs. Austin, TX, American Botanical Council, 1998; Reynolds J.E.F, ed. Martindale, the extra pharmacopoeia, 30th ed. London, Pharmaceutical Press, 1996.Lucida G.M. and Wallace J.M., In: Herbal medicines, A Clinicians Guide, Pharmaceutical Products Press, New York, London, 1998, 85—86.Lucida G.M. and Wallace J.M., In: Herbal medicines, A Clinicians Guide, Pharmaceutical Products Press, New York, London, 1998, 85—86.Eccles R., Menthol and related cooling compounds, J.Pharm. Pharmacol., 1994; 46: 18—63.Eccles R., Menthol and related cooling compounds, J.Pharm. Pharmacol., 1994; 46: 18—63.Bupesh G. et al. Antibacterial activity of Mentha piperita L. (peppermint) from leaf extracts — a medicinal plant. Acta agriculturae Slovenica, avgust 2007; 89(1): 73 — 79.Bupesh G. et al. Antibacterial activity of Mentha piperita L. (peppermint) from leaf extracts — a medicinal plant. Acta agriculturae Slovenica, avgust 2007; 89(1): 73 — 79.Faranak Ilkhani, Banafshe Hosseini, Ahmad Saedisomeolia. Niacin and Oxidative Stress: A Mini-Review. Journal of Nutritional Medicine and Diet Care, 2016, 2:014.Faranak Ilkhani, Banafshe Hosseini, Ahmad Saedisomeolia. Niacin and Oxidative Stress: A Mini-Review. Journal of Nutritional Medicine and Diet Care, 2016, 2:014.Aguilera-Nendez A., Fernandez-Lainez C. The Chemistry and Biochemistry of Niacin (B3). Food and Nutritional Components in Focus № 4.Aguilera-Nendez A., Fernandez-Lainez C. The Chemistry and Biochemistry of Niacin (B3). Food and Nutritional Components in Focus № 4.Durlach J., Bara M. Le magnésium en biologie et enMédecine. 2nd ed. Cachan, 2000.Durlach J., Bara M. Le magnésium en biologie et enMédecine. 2nd ed. Cachan, 2000.Terasaki M. and Rubin H. Evidence that intracellular magnesium is present in cells at a regulatory concentration for protein synthesis. Proc. Nati. Acad. Sci. USA, November 1985; 82: 7324—7326.Terasaki M. and Rubin H. Evidence that intracellular magnesium is present in cells at a regulatory concentration for protein synthesis. Proc. Nati. Acad. Sci. USA, November 1985; 82: 7324—7326.Tam M., S. Go´mez, M. Gonza´lez-Gross, A. Marcos. Possible roles of magnesium on the immune system. European Journal of Clinical Nutrition, 2003; 57:1193—1197.Tam M., S. Go´mez, M. Gonza´lez-Gross, A. Marcos. Possible roles of magnesium on the immune system. European Journal of Clinical Nutrition, 2003; 57:1193—1197.Fox C., Ramsoomair D., Carter C. Magnesium: its proven and potential clinical significance. South Med J, 2001; 94:1195—1201.Fox C., Ramsoomair D., Carter C. Magnesium: its proven and potential clinical significance. South Med J, 2001; 94:1195—1201.Borazan H., Kececioglu A., Okesli S., Otelcioglu S. Oral magnesium lozenge reduces postoperative sore throat: a randomized, prospective, placebo-controlled study. Anesthesiology. 2012 Sep; 117(3):512—8Borazan H., Kececioglu A., Okesli S., Otelcioglu S. Oral magnesium lozenge reduces postoperative sore throat: a randomized, prospective, placebo-controlled study. Anesthesiology. 2012 Sep; 117(3):512—8João Cleverson Gasparettoa, Cleverson Antônio Ferreira Martinsa, Sirlei Sayomi Hayashia, Michel Fleith Otukybc, Roberto Pontaroloa. Ethnobotanical and scientific aspects of Malva, sylvestris L.: a millennial herbal medicine. Journal of Pharmacy and Pharmacology, 2012; 64:172—189.João Cleverson Gasparettoa, Cleverson Antônio Ferreira Martinsa, Sirlei Sayomi Hayashia, Michel Fleith Otukybc, Roberto Pontaroloa. Ethnobotanical and scientific aspects of Malva, sylvestris L.: a millennial herbal medicine. Journal of Pharmacy and Pharmacology, 2012; 64:172—189.Cui Fan, Callen Pacier, Danik M. Martirosyan. Rose hip (Rosa canina L): A functional food perspective. Functional Foods in Health and Disease, 2014; 4(11):493—509.Cui Fan, Callen Pacier, Danik M. Martirosyan. Rose hip (Rosa canina L): A functional food perspective. Functional Foods in Health and Disease, 2014; 4(11):493—509.

The authors declare that there are no conflicts of interest present.