detinfДЕТСКИЕ ИНФЕКЦИИCHILDREN INFECTIONS2072-81072618-8139Association of Pediatricians and Infection Disease doctors10.22627/2072-8107-2019-18-1-60-62detinf-411Research ArticleВ ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУTO HELP OF PRACTICAL PEDIATRICSСпособность Klebsiella pneumoniae, выделенной при внутрибольничных инфекциях, к синтезу β-лактамазThe ability of K. pneumoniae isolated from nosocomial infections to the synthesis of β-lactamasehttps://orcid.org/0000-0001-6661-8717АтакишизадеС. А.AtakishizadehS. A.

Атакишизаде Садраддин Абдулла оглы - кандидат медицинских наук, доцент кафедры инфекционных болезней.

Баку

Atakishizadeh Sadraddin Abdulla - PhD, Associate Professor, Department of Infectious Diseases.

Baku

iris.ax@mil.ruАзербайджанский медицинский университетАзербайджанAzerbaijan Medical UniversityAzerbaijan2019060420191816062Copyright © Атакишизаде С.А., 20192019Атакишизаде С.А.Atakishizadeh S.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://detinf.elpub.ru/jour/article/view/411

В последние годы отмечается увеличение штаммов бактерий, способных синтезировать р-лактамазные ферменты широкого спектра (extended-spectrum β-lactamase (ESBL).

В работе изучена способность штаммов K. pneumoniae, выделенных от 30 больных в хирургических отделениях при инфекциях мочевыводящих путей (18), из областей хирургического вмешательства (7) и внутрибольничных пневмониях (5). Синтез ESBL K. pneumoniae был выявлен посредством фенотипического теста и с использованием двух дисков.

ESBL-синтезирующая способность K. pneumoniae обнаружена у 40% выделенных внутрибольничных штаммов. Установлено, что ESBL-позитивные штаммы K. pneumoniae достоверно чаще (р < 0,05) изолировались при инфекциях в области хирургического вмешательства и пневмонии (86% и 60% соответственно).

In recent years, there has been an increase in bacterial strains capable of synthesizing extended-spectrum β-lactamase (ESBL).

The study examined the ability of K. pneumoniae strains isolated from 30 patients in the surgical ward with urinary tract infections (1 8), from the areas of surgical intervention (7) and nosocomial pneumonia (5). Synthesis of ESBL K. pneumoniae was detected by means of a phenotypic test and using two disks.

The ESBL-positive K. pneumoniae was found in 40% of the isolated nosocomial strains. It was established that ESBL-positive strains of K. pneumoniae were significantly more often (p <0.05) isolated from infections in the area of surgical intervention and pneumonia (86% and 60%, respectively).

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The authors declare that there are no conflicts of interest present.