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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detinf</journal-id><journal-title-group><journal-title xml:lang="ru">ДЕТСКИЕ ИНФЕКЦИИ</journal-title><trans-title-group xml:lang="en"><trans-title>CHILDREN INFECTIONS</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-8107</issn><issn pub-type="epub">2618-8139</issn><publisher><publisher-name>Association of Pediatricians and Infection Disease doctors</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22627/2072-8107-2019-18-2-5-11</article-id><article-id custom-type="elpub" pub-id-type="custom">detinf-417</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕРЕДОВАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LEAD ARTICLE</subject></subj-group></article-categories><title-group><article-title>Шоковые состояния при острых инфекционных заболеваниях у детей</article-title><trans-title-group xml:lang="en"><trans-title>Shock in pediatric infection diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4762-5975</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блохин</surname><given-names>Б. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Blokhin</surname><given-names>B. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Блохин Борис Моисеевич - доктор медицинских наук, профессор, заведующий кафедрой поликлинической и неотложной педиатрии педиатрического факультета, РНИМУ им. Н.И. ПироговаМинздраваРоссии.</p><p>Москва.</p></bio><bio xml:lang="en"><p>MD, Рrofessor, chief of the department of outpatient and emergency pediatrics of the pediatric faculty of the Russian National Research Medical Universuty named after N.I. Pirogov.</p><p>Moscow.</p></bio><email xlink:type="simple">blokhinb@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9341-8139</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаврютина</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gavryutina</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доцент кафедры поликлинической и неотложной педиатрии педиатрического факультета, РНИМУ им. Н.И. Пирогова  Минздрава России.</p><p>Москва.</p></bio><bio xml:lang="en"/><email xlink:type="simple">montego@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н. И. Пирогова</institution></aff><aff xml:lang="en"><institution>Russian National Research Medical Universuty named after N.I. Pirogov</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>01</day><month>07</month><year>2019</year></pub-date><volume>18</volume><issue>2</issue><fpage>5</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Блохин Б.М., Гаврютина И.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Блохин Б.М., Гаврютина И.В.</copyright-holder><copyright-holder xml:lang="en">Blokhin B.M., Gavryutina I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://detinf.elpub.ru/jour/article/view/417">https://detinf.elpub.ru/jour/article/view/417</self-uri><abstract><p>Шок — смертельно опасное осложнение инфекционных заболеваний у детей. Основной причиной высокой смертности среди детского населения является поздняя диагностика и нерациональный подход к терапии шока. Вариабельность клинической картины требует формирования четкого алгоритма поиска методов диагностики и тактики лечения детей в зависимости от тяжести состояния.</p></abstract><trans-abstract xml:lang="en"><p>Shock is a frequent, lethally dangerous complication of infectious diseases in children. The main reason for high mortality among children population is late diagnostics and irrational therapy. The variability of clinical picture urges to develop a clear algorithm for searching shock markers and therapeutic approaches depending on the severity.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>шок</kwd><kwd>сепсис</kwd><kwd>септический шок</kwd><kwd>детские инфекции</kwd><kwd>осложнения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>shock</kwd><kwd>sepsis</kwd><kwd>septic shock</kwd><kwd>children infections</kwd><kwd>complications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Pediatric Critical Care Medicine: Volume 1: Care of the Critically Ill or Injured Child. Ed.: Derek S. Wheeler, Hector R. Wong, Thomas P. Shanley. Springer Science &amp; Business, 2014: 771.</mixed-citation><mixed-citation xml:lang="en">Pediatric Critical Care Medicine: Volume 1: Care of the Critically Ill or Injured Child. Ed.: Derek S. Wheeler, Hector R. Wong, Thomas P. Shanley. 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