detinfДЕТСКИЕ ИНФЕКЦИИCHILDREN INFECTIONS2072-81072618-8139Association of Pediatricians and Infection Disease doctors10.22627/2072-8107-2019-18-4-56-63detinf-460Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEW OF THE LITERATUREСовременный взгляд на проблему врожденной цитомегаловирусной инфекции: диагностика, лечение и профилактикаThe modern view of congenital cytomegalovirus infection: diagnosis, treatment and preventionhttps://orcid.org/0000-0002-0419-5410ХолодноваН. В.KholodnovaN. V.

Холоднова Наталья Витальевна, врач-неонатолог 8 инфекционного отделения для новорожденных 

Москва

Natalia Kholodnova, neonatologist of 8th infectious diseases department for newborns

Moscow

kholodnova.natalia@gmail.comhttps://orcid.org/0000-0002-0895-6707МазанковаЛ. Н.MazankovaL. N.

Мазанкова Людмила Николаевна, д.м.н., профессор, заведующая кафедрой детских инфекционных болезней

Москва

Lyudmila Mazankovа

Moscow

mazankova@list.ruhttps://orcid.org/0000-0002-0333-583XВольтерА. А.VolterA. A.

Вольтер Ангелина Алексеевна, клинический ординатор кафедры факультетской педиатрии

Москва

Angelina Volter

Moscow

angelina-volter@yandex.ruhttps://orcid.org/0000-0001-9030-6131ТуринаИ. Е.TurinaI. E.

Турина Ирина Евгеньевна, врач-неонатолог, педиатр, к.м.н., доцент кафедры педиатрии и детских инфекционных болезней 

Москва

Irina Turina

Moscow

turina11@mail.ruГБУЗ ДГКБ №9 им. Г.Н. Сперанского Минздрава РоссииG.N. Speransky City Children’s Hospital №9ФГБОУ «Российская медицинская академия непрерывного профессионального образования» МЗ РФRussian Medical Academy of Post-Graduate EducationФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава РоссииPirogov Russian National Research Medical UniversityФГАОУ ВО Первый Московский Государственный Медицинский Университет им. И.М. Сеченова Минздрава России (Сеченовский университет)I.M. Sechenov First Moscow State Medical University of the Russian Federation (Sechenov University)2019061220191845663Copyright © Холоднова Н.В., Мазанкова Л.Н., Вольтер А.А., Турина И.Е., 20192019Холоднова Н.В., Мазанкова Л.Н., Вольтер А.А., Турина И.Е.Kholodnova N.V., Mazankova L.N., Volter A.A., Turina I.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://detinf.elpub.ru/jour/article/view/460

Литературный обзор работ зарубежных и отечественных авторов посвящен современным подходам к диагностике, лечению и профилактике врожденной цитомегаловирусной инфекции (ВЦМВИ). Представлены данные международных консенсусов: «Консенсусное заявление европейских экспертов по диагностике и лечению ВЦМВИ», принятого группой по ВЦМВИ от Европейской ассоциации детских инфекционных болезней (ESPID) в Лейпциге (Германия) в 2015 году, и «Врожденная цитомегаловирусная инфекция у беременных и новорожденных: консенсуальные рекомендации по профилактике, диагностике и терапии» неофициальной Интернациональной группой по ВЦМВИ (ICCRG), созданной в Брисбене (Австралия) в 2015 году в рамках 5-й Международной конференции по врожденной цитомегалии, о доказательной базе лечения ВЦМВИ с применением противовирусных препаратов и иммунотерапии. Особое внимание уделено профилактике ЦМВИ как у беременных, так и у новорожденных, а также данные международных исследований о вакцинопрофилактике ЦМВИ.

A literature review of the works of foreign and domestic authors is devoted to modern approaches to the diagnosis, treatment and prevention of congenital cytomegalovirus infection (cCMV). The data of international consensuses are presented: «Congenital Cytomegalovirus: A European Expert Consensus Statement on Diagnosis and Management» adopted by the cCMV group from the European society for pediatric infectious diseases (ESPID) in Leipzig, Germany in 2015, and «Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy» by an informal International Congenital Cytomegalovirus Recommendations Group (ICCRG), established in Brisbane, Australia in 2015 as part of the 5th International cCMV Conference about evidence-based treatment cCMV using antiviral drugs and immunotherapy. Particular attention is paid to the prevention of cCMV in both pregnant and newborns, as well as data from international studies on the cytomegalovirus vaccination.

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The authors declare that there are no conflicts of interest present.