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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detinf</journal-id><journal-title-group><journal-title xml:lang="ru">ДЕТСКИЕ ИНФЕКЦИИ</journal-title><trans-title-group xml:lang="en"><trans-title>CHILDREN INFECTIONS</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-8107</issn><issn pub-type="epub">2618-8139</issn><publisher><publisher-name>Association of Pediatricians and Infection Disease doctors</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22627/2072-8107-2014-13-4-56-59</article-id><article-id custom-type="elpub" pub-id-type="custom">detinf-51</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>TO HELP OF PRACTICAL PEDIATRICS</subject></subj-group></article-categories><title-group><article-title>ЛИХОРАДКА ДЕНГЕ У ДЕТЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>DENGUE FEVER IN CHILDREN</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зверева</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zvereva</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доц. каф. инфекционных болезней у детей №2 РНИМУ; 117049, Москва, 4-й Добрынинский пер., 1, МДГКБ</p></bio><bio xml:lang="en"><p>СMS, Аssociate Professor, Russian National Research Medical University, Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ларичев</surname><given-names>В. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Larichev</surname><given-names>V. F.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сайфуллин</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sayfullin</surname><given-names>M. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьмина</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzmina</surname><given-names>N. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шамшева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shamsheva</surname><given-names>O. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бутенко</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Butenko</surname><given-names>A. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГОУ ВПО РНИМУ им. Н. И. Пирогова Минздрава России</institution></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ НИИ вирусологии им. Д. И. Ивановского Минздрава России</institution></aff><aff xml:lang="en"><institution>Ivanovsky Virology Institute</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ Инфекционная клиническая больница № 1 ДЗ г. Москвы</institution></aff><aff xml:lang="en"><institution>Infection deasese hospital № 13, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>01</day><month>09</month><year>2015</year></pub-date><volume>13</volume><issue>4</issue><fpage>56</fpage><lpage>59</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зверева Н.Н., Ларичев В.Ф., Сайфуллин М.А., Кузьмина Н.А., Шамшева О.В., Бутенко А.М., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Зверева Н.Н., Ларичев В.Ф., Сайфуллин М.А., Кузьмина Н.А., Шамшева О.В., Бутенко А.М.</copyright-holder><copyright-holder xml:lang="en">Zvereva N.N., Larichev V.F., Sayfullin M.A., Kuzmina N.A., Shamsheva O.V., Butenko A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://detinf.elpub.ru/jour/article/view/51">https://detinf.elpub.ru/jour/article/view/51</self-uri><abstract><p>В настоящее время в России ежегодно увеличивается количество случаев лихорадки денге у взрослого населения, тогда как в эндемичных районах, в связи с широким распространением заболевания чаще болеют дети, у которых заболевание имеет свои особенности. Приведен клинический пример заболевания у московской девочки, вернувшейся после отдыха в Таиланде — первый, зарегистрированный в России случай заболевания лихорадкой денге у ребенка. Обсуждаются проблемы диагностики заболевания, предложен алгоритм диагностики лихорадки денге. </p></abstract><trans-abstract xml:lang="en"><p>Currently in Russia number of cases of dengue fever in adults grows up, whereas in endemic areas, due to the wide spread of the disease is more common in children, which symptoms has its own characteristics. In the article is reviewed a clinical case of girl living in Moscow who has been returned from the Thailand vacation — the first registered case of dengue fever in childhood. In the article were discussed the problems of diagnostics of the disease, an algorithm for diagnosis of dengue fever.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лихорадка денге</kwd><kwd>дети</kwd><kwd>лейкопения</kwd><kwd>тромбоцитопения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Dengue fever</kwd><kwd>children</kwd><kwd>leukopenia</kwd><kwd>thrombocytopenia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ВОЗ. Денге и тяжелая денге. Информационный бюллетень № 117. — Сентябрь 2013 г. VOZ. Denge i tyazhelaya denge. Informatsionnyiy byulleten № 117. — Sentyabr 2013 g. [WHO. Dengue and severe dengue. Newsletter № 117. In September 2013]. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">ВОЗ. Денге и тяжелая денге. Информационный бюллетень № 117. — Сентябрь 2013 г. VOZ. Denge i tyazhelaya denge. Informatsionnyiy byulleten № 117. — Sentyabr 2013 g. [WHO. Dengue and severe dengue. Newsletter № 117. In September 2013]. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">СП 3.4.2318—08 «Санитарная охрана территории Российской Федерации». SP 3.4.2318—08 «Sanitarnaya ohrana territorii Rossiyskoy Federatsii» [sanitary protection of the territory of the Russian Federation]. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">СП 3.4.2318—08 «Санитарная охрана территории Российской Федерации». SP 3.4.2318—08 «Sanitarnaya ohrana territorii Rossiyskoy Federatsii» [sanitary protection of the territory of the Russian Federation]. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Приказ Департамента здравоохранения г. Москвы от 18 октября 2010 г. № 1850 «Об обеспечении мероприятий по предупреждению заноса и распространения инфекционных (паразитарных) болезней, требующих проведения мероприятий по санитарной охране территории города Москвы». Prikaz Departamenta zdravoohraneniya g. Moskvyi ot 18 oktyabrya 2010 g. N 1850 «Ob obespechenii meropriyatiy po preduprezhdeniyu zanosa i rasprostraneniya infektsionnyih (parazitarnyih) bolezney, trebuyuschih provedeniya meropriyatiy po sanitarnoy ohrane territorii goroda Moskvyi» [Order of the Department of Health, Moscow October 18, 2010 N 1850 «On provision of measures to prevent the introduction and spread of infectious (parasitic) diseases requiring measures for the sanitary protection of the territory of the city of Moscow»]. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Приказ Департамента здравоохранения г. Москвы от 18 октября 2010 г. № 1850 «Об обеспечении мероприятий по предупреждению заноса и распространения инфекционных (паразитарных) болезней, требующих проведения мероприятий по санитарной охране территории города Москвы». Prikaz Departamenta zdravoohraneniya g. Moskvyi ot 18 oktyabrya 2010 g. N 1850 «Ob obespechenii meropriyatiy po preduprezhdeniyu zanosa i rasprostraneniya infektsionnyih (parazitarnyih) bolezney, trebuyuschih provedeniya meropriyatiy po sanitarnoy ohrane territorii goroda Moskvyi» [Order of the Department of Health, Moscow October 18, 2010 N 1850 «On provision of measures to prevent the introduction and spread of infectious (parasitic) diseases requiring measures for the sanitary protection of the territory of the city of Moscow»]. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Сергиев В.А. Появление экзотических переносчиков арбовирусных лихорадок — новая недостаточно оцениваемая биологическая угроза южным регионам России // Журнал инфектологии. — № 1. — 2011. Sergiev V.A. Poyavlenie ekzoticheskih perenoschikov arbovirusnyih lihoradok — novaya nedostatochno otsenivaemaya biologicheskaya ugroza yuzhnyim regionam Rossii [The appearance of exotic arbovirus vectors fevers — a new biological threat underestimate the southern regions of Russia ] // Zhurnal Infektologii. — № 1. — 2011 g. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Сергиев В.А. Появление экзотических переносчиков арбовирусных лихорадок — новая недостаточно оцениваемая биологическая угроза южным регионам России // Журнал инфектологии. — № 1. — 2011. Sergiev V.A. Poyavlenie ekzoticheskih perenoschikov arbovirusnyih lihoradok — novaya nedostatochno otsenivaemaya biologicheskaya ugroza yuzhnyim regionam Rossii [The appearance of exotic arbovirus vectors fevers — a new biological threat underestimate the southern regions of Russia ] // Zhurnal Infektologii. — № 1. — 2011 g. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Dengue: guidelines for diagnosis, treatment, prevention and control. — New edition. WHO. — 2009.</mixed-citation><mixed-citation xml:lang="en">Dengue: guidelines for diagnosis, treatment, prevention and control. — New edition. WHO. — 2009.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Halstead Scott B. Dengue 2008 by Imperial College Press ISBN-13 978-1-84816-228-0.</mixed-citation><mixed-citation xml:lang="en">Halstead Scott B. Dengue 2008 by Imperial College Press ISBN-13 978-1-84816-228-0.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Halstead Scott B et all. Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored // Emerg Infect Dis. — Dec. — 2002; 8 (12): 1474—1479.</mixed-citation><mixed-citation xml:lang="en">Halstead Scott B et all. Dengue Hemorrhagic Fever in Infants: Research Opportunities Ignored // Emerg Infect Dis. — Dec. — 2002; 8 (12): 1474—1479.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Nguyen Thanh Hung et all. Dengue Hemorrhagic Fever in Infants: A Study of Clinical and Cytokine Profiles // The Journal of Infectious Diseases. —V. 189. — 221—232.</mixed-citation><mixed-citation xml:lang="en">Nguyen Thanh Hung et all. Dengue Hemorrhagic Fever in Infants: A Study of Clinical and Cytokine Profiles // The Journal of Infectious Diseases. —V. 189. — 221—232.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Hongsiriwon S. Dengue hemorrhagic fever in infants // Southeast Asian J Trop Med Public Health. — 2002. — Mar; 33 (1): 49—55.</mixed-citation><mixed-citation xml:lang="en">Hongsiriwon S. Dengue hemorrhagic fever in infants // Southeast Asian J Trop Med Public Health. — 2002. — Mar; 33 (1): 49—55.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Hammond Samantha Nadia. Differences in dengue severity in infants, children, and adults in a 3-year hospital-based study in Nicaragua // Am J Trop Med Hyg. — December. — 2005 — V. 73, № 6 1063—1070.</mixed-citation><mixed-citation xml:lang="en">Hammond Samantha Nadia. Differences in dengue severity in infants, children, and adults in a 3-year hospital-based study in Nicaragua // Am J Trop Med Hyg. — December. — 2005 — V. 73, № 6 1063—1070.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Khoa T.D. Thai mail et all. Age-Specificity of Clinical Dengue during Primary and Secondary Infections // PLOS Neglected Tropical Diseases Published: June 21. — 2011. — DOI: 10.1371/journal.pntd.0001180.</mixed-citation><mixed-citation xml:lang="en">Khoa T.D. Thai mail et all. Age-Specificity of Clinical Dengue during Primary and Secondary Infections // PLOS Neglected Tropical Diseases Published: June 21. — 2011. — DOI: 10.1371/journal.pntd.0001180.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Guzman M.G. et al. Dengue hemorrhagic fever in Cuba, 1981: a retrospective seroepidemiologic study // Am J Trop Med Hyg. — 1990; 42 (2): 179—184.</mixed-citation><mixed-citation xml:lang="en">Guzman M.G. et al. Dengue hemorrhagic fever in Cuba, 1981: a retrospective seroepidemiologic study // Am J Trop Med Hyg. — 1990; 42 (2): 179—184.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kalayanarooj S. et al. Early clinical and laboratory indicators of acute dengue illness // J Infect Dis. — 1997; 176 (2): 313—321.</mixed-citation><mixed-citation xml:lang="en">Kalayanarooj S. et al. Early clinical and laboratory indicators of acute dengue illness // J Infect Dis. — 1997; 176 (2): 313—321.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Vaughn D.W. et al. Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity // J Infect Dis. — 2000; 181 (1): 2—9.</mixed-citation><mixed-citation xml:lang="en">Vaughn D.W. et al. Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity // J Infect Dis. — 2000; 181 (1): 2—9.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Vaughn D.W. Invited commentary: dengue lessons from Cuba // Am Epidemiol. — 2000; 152 (9): 800—803.</mixed-citation><mixed-citation xml:lang="en">Vaughn D.W. Invited commentary: dengue lessons from Cuba // Am Epidemiol. — 2000; 152 (9): 800—803.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Nguyen Thanh Hung Volume replacement in infants with dengue hemorrhagic fever/dengue shock syndrome // Am. J. Trop. Med. Hyg. — 74 (4). — 2006. — Р. 684—691.</mixed-citation><mixed-citation xml:lang="en">Nguyen Thanh Hung Volume replacement in infants with dengue hemorrhagic fever/dengue shock syndrome // Am. J. Trop. Med. Hyg. — 74 (4). — 2006. — Р. 684—691.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Сайфуллин М.А., Ларичев В.Ф., Акиншина Ю.А. и др. Завозные случаи лихорадки Денге в Москве в 2009—2011 гг.: особенности клиники и лабораторных показателей // Эпидемиология и инфекционные болезни. — 2012. — № 6. — С. 29—35. Sayfullin M.A., Larichev V.F., Akinshina Yu.A. i dr. Zavoznyie sluchai lihoradki denge v Moskve v 2009—2011 gg.: osobennosti kliniki i laboratornyih pokazateley [Imported cases of dengue fever in Moscow in 2009—2011 yy.: particular clinic and laboratory parameters] // Epidemiologiya i Infektsionnyie Bolezni. — 2012. — № 6. — S. 29—35. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Сайфуллин М.А., Ларичев В.Ф., Акиншина Ю.А. и др. Завозные случаи лихорадки Денге в Москве в 2009—2011 гг.: особенности клиники и лабораторных показателей // Эпидемиология и инфекционные болезни. — 2012. — № 6. — С. 29—35. Sayfullin M.A., Larichev V.F., Akinshina Yu.A. i dr. Zavoznyie sluchai lihoradki denge v Moskve v 2009—2011 gg.: osobennosti kliniki i laboratornyih pokazateley [Imported cases of dengue fever in Moscow in 2009—2011 yy.: particular clinic and laboratory parameters] // Epidemiologiya i Infektsionnyie Bolezni. — 2012. — № 6. — S. 29—35. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Ларичев В.Ф., Сайфуллин М.А., Акиншина Ю.А. и др. Завозные случаи арбовирусных инфекций в Российской Федерации Эпидемиология и инфекционные болезни. — 2012. — № 1. — С. 35—38. Larichev V.F., Sayfullin M.A., Akinshina Yu.A. i dr. Zavoznyie sluchai arbovirusnyih infektsiy v Rossiyskoy Federatsii [Imported cases of arbovirus infections in the Russian Federation epidemiology and infectious diseases ] // Epidemiologiya i Infektsionnyie Bolezni. — 2012. — № 1. — S. 35—38. (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Ларичев В.Ф., Сайфуллин М.А., Акиншина Ю.А. и др. Завозные случаи арбовирусных инфекций в Российской Федерации Эпидемиология и инфекционные болезни. — 2012. — № 1. — С. 35—38. Larichev V.F., Sayfullin M.A., Akinshina Yu.A. i dr. Zavoznyie sluchai arbovirusnyih infektsiy v Rossiyskoy Federatsii [Imported cases of arbovirus infections in the Russian Federation epidemiology and infectious diseases ] // Epidemiologiya i Infektsionnyie Bolezni. — 2012. — № 1. — S. 35—38. (In Russ.)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
