detinfДЕТСКИЕ ИНФЕКЦИИCHILDREN INFECTIONS2072-81072618-8139Association of Pediatricians and Infection Disease doctors10.22627/2072-8107-2020-19-3-58-64detinf-526Research ArticleВ ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУTO HELP OF PRACTICAL PEDIATRICSРоль инфекционных агентов в патогенезе дерматозов у детей и подростковSouth Ural state medical University, Department of Dermatovenerologyhttps://orcid.org/0000-0002-9085-6229ЛетяеваО. И.LetyaevaO. I.

Доктор медицинских наук, профессор кафедры дерматовенерологии.

Челябинск

Olga-letyaeva@yandex.ruФГБОУ ВО Южно-уральский государственный медицинский университетРоссияSouth Ural state medical University, Department of DermatovenerologyRussian Federation2020300920201935864Copyright © Летяева О.И., 20202020Летяева О.И.Letyaeva O.I.This work is licensed under a Creative Commons Attribution 4.0 License.https://detinf.elpub.ru/jour/article/view/526

Статья посвящена современным представлениям о роли микробных агентов в патогенезе наиболее распространенных дерматозов в педиатрической практике.

Показано значение микробиома кожи и очагов хронического воспаления в индукции и поддержании патологического процесса в дерме при атопическом дерматите, псориазе.

Представлены собственные клинические наблюдения двух девочек в возрасте 12 лет с диагнозом: псориаз вульгарный с поражением кожи, волосистой части головы и в возрасте 5 лет с диагнозом: атопический дерматит, детская фаза, эритематозно-сквамозная форма, легкое течение.

Препарат активированного цинка пиритиона обладает противовоспалительной, противогрибковой и противомикробной активностью, высоким профилем безопасности и может использоваться для контроля воспаления и коррекции микробиома кожи. Использование препарата активированного цинка пиритиона способствует существенному снижению необходимости применения наружных кортикостероидов.

The article discusses modern ideas about the role of microbial agents in the pathogenesis of the most common dermatoses in pediatric practice.

The paper shows the importance of the skin microbiome and foci of chronic inflammation in the induction and maintenance of the pathological process in the dermis in atopic dermatitis, psoriasis.

Presented own clinical observations of two girls at the age of 1 2 years with a diagnosis: vulgar psoriasis with lesions of the skin, scalp, and at the age of 5 years with a diagnosis of atopic dermatitis, childhood phase, erythematous-squamous form, mild course.

The preparation of activated zinc pyrithione has anti-inflammatory, antifungal and antimicrobial activity, a high safety profile and can be used to control inflammation and correct the skin microbiome. The use of the preparation of activated zinc pyrithione significantly reduces the need for external corticosteroids.

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The authors declare that there are no conflicts of interest present.