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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detinf</journal-id><journal-title-group><journal-title xml:lang="ru">ДЕТСКИЕ ИНФЕКЦИИ</journal-title><trans-title-group xml:lang="en"><trans-title>CHILDREN INFECTIONS</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-8107</issn><issn pub-type="epub">2618-8139</issn><publisher><publisher-name>Association of Pediatricians and Infection Disease doctors</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22627/2072-8107-2021-20-2-64-67</article-id><article-id custom-type="elpub" pub-id-type="custom">detinf-602</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE FROM PRACTICAL</subject></subj-group></article-categories><title-group><article-title>Клинический случай ветряной оспы, осложненной менингоэнцефалитом и отеком головного мозга, в сочетании с новой коронавирусной инфекцией (COVID-19) у ребёнка 5 лет</article-title><trans-title-group xml:lang="en"><trans-title>A clinical case of chickenpox complicated by meningoencephalitis and cerebral edema in combination with a novel coronavirus infection (COVID-19) in a 5-year-old child</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2836-4191</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьмина</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzmina</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузьмина Мария Николаевна - кандидат медицинских наук, ассистент кафедры инфекционных болезней, эпидемиологии и детских инфекций</p></bio><bio xml:lang="en"><p>Maria Kuzmina, PhD, assistant</p></bio><email xlink:type="simple">mnkuzmina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1998-7832</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Климовицкая</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Klimovitskaya</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Климовицкая Елизавета Генриховна - кандидат медицинских наук, доцент кафедры инфекционных болезней, эпидемиологии и детских инфекций</p></bio><bio xml:lang="en"><p>Elizaveta Klimovitskaya, PhD, associate Professor</p></bio><email xlink:type="simple">k337003@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5562-7888</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ешмолов</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Eshmolov</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ешмолов Сергей Николаевич - кандидат медицинских наук, ассистент кафедры инфекционных болезней, эпидемиологии и детских инфекций</p></bio><bio xml:lang="en"><p>Sergey Eshmolov, PhD, assistant</p></bio><email xlink:type="simple">doctorsn@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2821-433X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ситников</surname><given-names>И. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Sitnikov</surname><given-names>I. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ситников Иван Германович - доктор медицинских наук, профессор, заведующий кафедрой инфекционных болезней, эпидемиологии и детских инфекций</p></bio><bio xml:lang="en"><p>Ivan Sitnikov, MD, Professor</p></bio><email xlink:type="simple">sitnikov@ysmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1890-5505</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Елякова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Elyakova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Елякова Елена Вячеславовна - заведующая отделением №2</p><p>Ярославль</p></bio><bio xml:lang="en"><p>Elena Elyakova</p><p>Yaroslavl</p></bio><email xlink:type="simple">elyakova.elena1966@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ВО Ярославский государственный медицинский университет МЗ РФ<country>Россия</country></aff><aff xml:lang="en">Yaroslavl state medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ГБУЗ ЯО Инфекционная клиническая больница<country>Россия</country></aff><aff xml:lang="en">Infectious Clinical Hospital<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>08</day><month>07</month><year>2021</year></pub-date><volume>20</volume><issue>2</issue><fpage>64</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кузьмина М.Н., Климовицкая Е.Г., Ешмолов С.Н., Ситников И.Г., Елякова Е.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Кузьмина М.Н., Климовицкая Е.Г., Ешмолов С.Н., Ситников И.Г., Елякова Е.В.</copyright-holder><copyright-holder xml:lang="en">Kuzmina M.N., Klimovitskaya E.G., Eshmolov S.N., Sitnikov I.G., Elyakova E.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://detinf.elpub.ru/jour/article/view/602">https://detinf.elpub.ru/jour/article/view/602</self-uri><abstract><p>Новая коронавирусная инфекция COVID-19 у детей в целом протекает благоприятно, однако в сочетании с другими острыми инфекционными заболеваниями, фоновой патологией и нарушениями иммунной реактивности может представлять особую угрозу.</p><p>В статье представлен клинический случай ветряной оспы, осложнённой менингоэнцефалитом и отёком головного мозга, в сочетании с COVID-19 у ребёнка 5 лет.</p><p>Ветряная оспа протекала не совсем типично: на фоне фебрильной температуры имели место скудная пятнисто-папулёзная сыпь с появившимися позднее единичными везикулами, отсутствием элементов на слизистых и развитием неврологической симптоматики в первые сутки заболевания. COVID-19 характеризовался волнообразным течением с лихорадкой до 39,1 °С, явлениями тонзиллита и воспалительными изменениями в анализе крови.</p></abstract><trans-abstract xml:lang="en"><p>The new coronavirus infection COVID-1 9 in children generally proceeds favorably, but in combination with other acute infectious diseases and in persons with background pathology and impaired immune reactivity may pose a particular threat.</p><p>The article presents a clinical case of chickenpox, complicated by meningoencephalitis and cerebral edema, in combination with COVID-1 9 in a 5-year-old child. Chickenpox was not quite typical: against the background of febrile temperature, there was a scanty spot-papular rash with single vesicles that appeared later, the absence of elements on the mucous membranes and the development of neurological symptoms in the first day of the disease. CОVID-1 9 was characterized by a wave-like course with fever up to 39,1 °C, tonsillitis phenomena and inflammatory changes in the blood test.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>COVID-19</kwd><kwd>ветряная оспа</kwd><kwd>менингоэнцефалит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>COVID-19</kwd><kwd>chickenpox</kwd><kwd>meningoencephalitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Скрипченко Н.В. Нейроинфекции у детей (коллективная монография). Санкт-Петербург: «Тактик-Студио», 2015:856 с.</mixed-citation><mixed-citation xml:lang="en">Skripchenko N.V. Neuroinfections in children (collective monograph). 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