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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detinf</journal-id><journal-title-group><journal-title xml:lang="ru">ДЕТСКИЕ ИНФЕКЦИИ</journal-title><trans-title-group xml:lang="en"><trans-title>CHILDREN INFECTIONS</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-8107</issn><issn pub-type="epub">2618-8139</issn><publisher><publisher-name>Association of Pediatricians and Infection Disease doctors</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22627/2072-8107-2021-20-3-5-10</article-id><article-id custom-type="elpub" pub-id-type="custom">detinf-613</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Клинико-эпидемиологические особенности течения новой коронавирусной инфекции COVID-19 у детей в периоды подъема заболеваемости в городе Москве в 2020—2021 гг.</article-title><trans-title-group xml:lang="en"><trans-title>Clinical and epidemiological features of the course of the new coronavirus infection COVID-19 in children during periods of an increase in the incidence in Moscow in 2020-2021</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0895-6707</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазанкова</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazankova</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мазанкова Людмила Николаевна – доктор медицинских наук, профессор, заведующая кафедрой детских инфекционных болезней педиатрического факультета РМАНПО, главный внештатный специалист по инфекционным болезням у детей.</p><p>Москва.</p></bio><bio xml:lang="en"><p>MD, Professor.</p><p>Moscow.</p></bio><email xlink:type="simple">mazankova@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0380-7515</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самитова</surname><given-names>Э. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Samitova</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самитова Эльмира Растямовна – кандидат медицинских наук, заместитель главного врача по инфекциям ДГКБ им. З.А. Башляевой; ассистент кафедры детских инфекционных болезней РМАНПО.</p><p>Москва.</p></bio><bio xml:lang="en"><p>PhD.</p><p>Moscow.</p></bio><email xlink:type="simple">samitova_rudn@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3181-9601</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Османов</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Osmanov</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Османов Исмаил Магомедтагирович – доктор медицинских наук, профессор, главный врач ДГКБ им. З.А. Башляевой, главный внештатный детский специалист-нефролог.</p><p>Москва.</p></bio><bio xml:lang="en"><p>MD, Professor.</p><p>Moscow.</p></bio><email xlink:type="simple">osmanovim@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9850-6779</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Афуков</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Afukov</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Афуков Иван Игоревич – кандидат медицинских наук, доцент кафедры детской хирургии, РНИМУ им. Н.И. Пирогова, заведующий отделением реанимации ДГКБ № 13 им. Н.Ф. Филатова.</p><p>Москва.</p></bio><bio xml:lang="en"><p>PhD.</p><p>Moscow.</p></bio><email xlink:type="simple">afukovdoc@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7557-2236</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Драчева</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dracheva</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Драчева Наталья Алексеевна - врач-педиатр, аспирант кафедры детских инфекционных болезней, РМАНПО МЗ РФ.</p><p>Москва.</p></bio><bio xml:lang="en"><p>Moscow.</p></bio><email xlink:type="simple">tan1809@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2686-8284</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малахов</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Malakhov</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малахов Александр Борисович – доктор медицинских наук, профессор кафедры детских болезней Клинического института детского здоровья им. Н.Ф. Филатова, Первый МГМУ им. И.М. Сеченова (Сеченовский Университет), Морозовская ДГКБ, главный внештатный детский специалист-пульмонолог Департамента здравоохранения г. Москвы.</p><p>Москва.</p></bio><bio xml:lang="en"><p>MD, Professor.</p><p>Moscow.</p></bio><email xlink:type="simple">alexis4591m@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8421-1694</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гутырчик</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gutyrchik</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гутырчик Татьяна Александровна - врач-педиатр, аспирант, Морозовская ДГКБ.</p><p>Москва.</p></bio><bio xml:lang="en"><p>Moscow.</p></bio><email xlink:type="simple">tanya_2904@list.ru</email><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4228-9044</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акимкин</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Akimkin</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Акимкин Василий Геннадьевич - академик РАН, доктор медицинских наук, профессор, директор Центрального НИИ эпидемиологии Роспотребнадзора.</p><p>Москва.</p></bio><bio xml:lang="en"><p>MD, Professor, Academician of the Russian Academy of Sciences.</p><p>Moscow.</p></bio><email xlink:type="simple">crie@pcr.ru</email><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3612-1889</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Плоскирева</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ploskireva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Плоскирева Антонина Александровна – доктор медицинских наук, заместитель директора по клинической работе ЦНИИ Эпидемиологии Роспотребнадзора.</p><p>Москва.</p></bio><bio xml:lang="en"><p>MD.</p><p>Moscow.</p></bio><email xlink:type="simple">antonina@ploskireva.com</email><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9716-2211</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таранов</surname><given-names>Л. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Taranov</surname><given-names>L. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Таранов Леонид Олегович - клинический ординатор РНИМУ им. Н.И. Пирогова Минздрава России.</p><p>Москва.</p></bio><bio xml:lang="en"><p>Moscow.</p></bio><email xlink:type="simple">leotar1997@gmail.ru</email><xref ref-type="aff" rid="aff-8"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Российская медицинская академия непрерывного профессионального образования МЗ РФ; Детская городская клиническая больница имени З. А. Башляевой ДЗМ<country>Россия</country></aff><aff xml:lang="en">Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation; Children's City Clinical Hospital named after Z.A. Bashlyaeva<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Детская городская клиническая больница имени З. А. Башляевой ДЗМ<country>Россия</country></aff><aff xml:lang="en">Children's City Clinical Hospital named after Z.A. Bashlyaeva<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Российский национальный исследовательский медицинский университет им. Н.И. Пирогова Минздрава России; Детская городская клиническая больница № 13 им. Н.Ф. Филатова<country>Россия</country></aff><aff xml:lang="en">Russian National Medical Research University named after N.I. Pirogov of the Ministry of Health of Russia; Children's City Clinical Hospital No 13 named after N.F. Filatov<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">Российская медицинская академия непрерывного профессионального образования МЗ РФ<country>Россия</country></aff><aff xml:lang="en">Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru">Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет); Морозовская детская городская клиническая больница Департамента здравоохранения г. Москвы<country>Россия</country></aff><aff xml:lang="en">I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (I.M. Sechenov University); Morozovskaya Children's City Clinical Hospital of the Moscow Department of Health<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru">Морозовская детская городская клиническая больница Департамента здравоохранения г. Москвы<country>Россия</country></aff><aff xml:lang="en">Morozovskaya Children's City Clinical Hospital of the Moscow Department of Health<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru">Центральный научно-исследовательский институт эпидемиологии Роспотребнадзора<country>Россия</country></aff><aff xml:lang="en">Central Research Institute of Epidemiology of Rospotrebnadzor<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru">Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России (Сеченовский Университет)<country>Россия</country></aff><aff xml:lang="en">I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (I.M. Sechenov University)<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>05</day><month>10</month><year>2021</year></pub-date><volume>20</volume><issue>3</issue><fpage>5</fpage><lpage>10</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мазанкова Л.Н., Самитова Э.Р., Османов И.М., Афуков И.И., Драчева Н.А., Малахов А.Б., Гутырчик Т.А., Акимкин В.Г., Плоскирева А.А., Таранов Л.О., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Мазанкова Л.Н., Самитова Э.Р., Османов И.М., Афуков И.И., Драчева Н.А., Малахов А.Б., Гутырчик Т.А., Акимкин В.Г., Плоскирева А.А., Таранов Л.О.</copyright-holder><copyright-holder xml:lang="en">Mazankova L.N., Samitova E.R., Osmanov I.M., Afukov I.I., Dracheva N.A., Malakhov A.B., Gutyrchik T.A., Akimkin V.G., Ploskireva A.A., Taranov L.O.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://detinf.elpub.ru/jour/article/view/613">https://detinf.elpub.ru/jour/article/view/613</self-uri><abstract><sec><title>Цель</title><p>Цель: выявить особенности течения инфекции COVID-19 у детей в разные периоды эпидемиологического подъема заболеваемости в городе Москве в 2020—2021 гг.</p></sec><sec><title>Результаты</title><p>Результаты: В статье представлено наблюдение за 1561 ребенком, госпитализированным в ГБУЗ «Детская городская клиническая больница имени З.А. Башляевой ДЗМ» с диагнозом новая коронавирусная инфекция COVID-19 в периоды эпидемиологического подъема заболеваемости («2-й и 3-й волн COVID-19»). Показано увеличение числа госпитализированных детей во время «3-й волны COVID-19», ранние сроки поступления от начала заболевания, в связи с отсутствием эффекта лечения в амбулаторных условиях, преобладание детей школьного возраста и подростков, преимущественное течение инфекции с развитием вирусной пневмонии КТ2-3, реже КТ3-4, сокращение числа детей с MIS-синдром в 10 раз, удлинение периода вирусовыделения у пациентов.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: to identify the features of COVID-19 infection in children at different periods of the epidemiological rise in the incidence in the city of Moscow.</p></sec><sec><title>Results</title><p>Results. The article presents the observation of 1561 children hospitalized in the State Medical Institution «Children's City Clinical Hospital named after Z. A. Bash-lyaeva DZM» with a diagnosis of a new coronavirus infection COVID-19 during the periods of epidemiological rises in morbidity («2nd and 3rd waves of COVID-19»). An increase in the number of hospitalized children during the «3rd wave of COVID-19», early admission dates from the onset of the disease, due to the lack of treatment effect in outpatient settings, the predominance of school-age children and adolescents, the predominant course of infection with the development of viral pneumonia CT2-3, less often CT3-4, a 10-fold reduction in the number of children with MIS-syndrome, an elongation of the period of viral release in patients.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>новая коронавирусная инфекция</kwd><kwd>SARS-CoV-2</kwd><kwd>COVID-19</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>new coronavirus infection</kwd><kwd>SARS-CoV-2</kwd><kwd>COVID-19</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ilias N. 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