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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detinf</journal-id><journal-title-group><journal-title xml:lang="ru">ДЕТСКИЕ ИНФЕКЦИИ</journal-title><trans-title-group xml:lang="en"><trans-title>CHILDREN INFECTIONS</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-8107</issn><issn pub-type="epub">2618-8139</issn><publisher><publisher-name>Association of Pediatricians and Infection Disease doctors</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22627/2072-8107-2024-23-1-35-43</article-id><article-id custom-type="elpub" pub-id-type="custom">detinf-914</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW OF THE LITERATURE</subject></subj-group></article-categories><title-group><article-title>Неиммунная водянка плода: этиология,  патогенез, особенности диагностики  и лечения у плода и новорожденного</article-title><trans-title-group xml:lang="en"><trans-title>Non-immune hydrops fetalis: etiology, pathogenesis, features of diagnosis  and treatment in the fetus and newborn</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0762-2086</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Думова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dumova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Думова Светлана Владимировна - к.м.н., доцент кафедры госпитальной педиатрии им. академика В.А. Таболина</p><p>Москва </p></bio><bio xml:lang="en"><p>Dumova S. V.</p><p> Moscow</p></bio><email xlink:type="simple">s-dumova16@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7305-9036</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саркисян</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sarkisyan</surname><given-names>H. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Саркисян Егине Альбертовна - к.м.н, доцент кафедры госпитальной педиатрии им. академика В.А. Таболина </p><p>Москва </p></bio><bio xml:lang="en"><p>Sarkisyan H. A.</p><p>Moscow</p></bio><email xlink:type="simple">heghinesarg@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1547-0016</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чугунова</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Chugunova</surname><given-names>O. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чугунова Ольга Леонидовна - д.м.н., проф. кафедры госпитальной педиатрии им. академика В.А. Таболина</p><p> Москва </p></bio><bio xml:lang="en"><p>Chugunova O. L.</p><p>Moscow</p></bio><email xlink:type="simple">ol_chugunova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-8515-9100</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прохоров</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokhorov</surname><given-names>I. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Прохоров Иван Дмитриевич - студент 6 курса педиатрического факультета </p><p>Москва</p></bio><bio xml:lang="en"><p>Prokhorov I. D.</p><p>Moscow</p></bio><email xlink:type="simple">iva.prohorov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-7728-5624</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаева</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaeva</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николаева Мария Игоревна -студент 6 курса педиатрического факультета </p><p>Москва</p></bio><bio xml:lang="en"><p> Nikolaeva M. I.</p><p>Moscow</p></bio><email xlink:type="simple">nik.masha2000@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-9038-4350</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глоба</surname><given-names>М. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Globa</surname><given-names>M. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Глоба Мария Романовна - студент 6 курса педиатрического факультета </p><p>Москва</p></bio><bio xml:lang="en"><p>Globa M. R.</p><p>Moscow</p></bio><email xlink:type="simple">globamasha@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-2133-5146</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нам</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Nam</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нам Дарина Игоревна - студент 6 курса педиатрического факультета  </p><p>Москва</p></bio><bio xml:lang="en"><p>Nam D. I.</p><p>Moscow</p></bio><email xlink:type="simple">darinafox150@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3091-6170</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Журавлева</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuravleva</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Журавлева Ирина Витальевна -  клинический ординатор кафедры госпитальной педиатрии им. академика В.А. Таболина педиатрическогофакультета </p><p>Москва</p></bio><bio xml:lang="en"><p> Zhuravleva I. V.</p><p>Moscow</p></bio><email xlink:type="simple">ira.sindyankina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9567-6761</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шумилов</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shumilov</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шумилов Петр Валентинович - д.м.н., профессор, заведующий кафедрой госпитальной педиатрии им. академика В.А. Таболина</p><p>Москва</p></bio><bio xml:lang="en"><p>Shumilov P. V.</p><p>Moscow</p></bio><email xlink:type="simple">peter_shumilov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Российский национальный исследовательский медицинский университет имени Н.И. Пирогова<country>Россия</country></aff><aff xml:lang="en">Pirogov Russian National Research Medical University of the Ministry of Health<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>23</day><month>03</month><year>2024</year></pub-date><volume>23</volume><issue>1</issue><fpage>35</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Думова С.В., Саркисян Е.А., Чугунова О.Л., Прохоров И.Д., Николаева М.И., Глоба М.Р., Нам Д.И., Журавлева И.В., Шумилов П.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Думова С.В., Саркисян Е.А., Чугунова О.Л., Прохоров И.Д., Николаева М.И., Глоба М.Р., Нам Д.И., Журавлева И.В., Шумилов П.В.</copyright-holder><copyright-holder xml:lang="en">Dumova S.V., Sarkisyan H.A., Chugunova O.L., Prokhorov I.D., Nikolaeva M.I., Globa M.R., Nam D.I., Zhuravleva I.V., Shumilov P.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://detinf.elpub.ru/jour/article/view/914">https://detinf.elpub.ru/jour/article/view/914</self-uri><abstract><p>Неиммунная водянка плода — полиэтиологическое заболевание, характеризующееся высокой перинатальной смертностью. Причины развития неиммунной водянки плода многообразны, но в первую очередь связаны с заболеваниями сердечно-сосудистой системы, инфекционными заболеваниями, генными и хромосомными болезнями. В связи с этим нет единого подхода к лечению этого крайне опасного патологического состояния, которое требует совместной работы специалистов разных специальностей: акушеров-гинекологов, неонатологов, кардиологов, хирургов, гематологов и генетиков. В данном статье представлен обзор современных литературных данных об этиологии, патогенезе, клинических проявлениях, возможностях лечения и исходах неиммунной водянки плода</p></abstract><trans-abstract xml:lang="en"><p>Non-immune hydrops fetalis is a polyetiological disease characterized by high perinatal mortality. The development of non-immune fetal hydrops is associated with diseases of the cardiovascular and lymphatic systems, genetic and chromosomal diseases, infectious agents and many other reasons. In this regard, there is no single approach to the treatment of this extremely dangerous pathological condition, which requires the joint work of specialists from different specialties: obstetricians-gynecologists, neonatologists, cardiologists, surgeons, hematologists and geneticists. This article provides a review of current literature data on the etiology, pathogenesis, clinical manifestations, treatment and outcomes of non-immune hydrops fetalis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>неиммунная водянка плода</kwd><kwd>парвовирусная инфекция</kwd><kwd>герпетическая инфекция</kwd><kwd>токсоплазмоз</kwd><kwd>сифилис</kwd><kwd>«зеркальный» синдром</kwd><kwd>нарушение сердечной проводимости у плода</kwd><kwd>фетальный гепатит</kwd><kwd>фетальный миокардит</kwd><kwd>врожденные пороки развития</kwd></kwd-group><kwd-group xml:lang="en"><kwd>non-immune hydrops fetalis</kwd><kwd>parvovirus infection</kwd><kwd>herpetic infection</kwd><kwd>toxoplasmosis</kwd><kwd>syphilis</kwd><kwd>“mirror” syndrome</kwd><kwd>cardiac conduction disorder in the fetus</kwd><kwd>fetal hepatitis</kwd><kwd>fetal myocarditis</kwd><kwd>congenital malformations</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кадырбердиева Ф.З., Шмаков Р.Г., Бокерия Е.Л. 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