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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">detinf</journal-id><journal-title-group><journal-title xml:lang="ru">ДЕТСКИЕ ИНФЕКЦИИ</journal-title><trans-title-group xml:lang="en"><trans-title>CHILDREN INFECTIONS</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-8107</issn><issn pub-type="epub">2618-8139</issn><publisher><publisher-name>Association of Pediatricians and Infection Disease doctors</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22627/2072-8107-2024-23-1-44-48</article-id><article-id custom-type="elpub" pub-id-type="custom">detinf-915</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW OF THE LITERATURE</subject></subj-group></article-categories><title-group><article-title>Спарганоз</article-title><trans-title-group xml:lang="en"><trans-title>Sparganosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6737-4184</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чуелов</surname><given-names>С. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Chuelov</surname><given-names>S. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чуелов Сергей Борисович - д.м.н., профессор кафедры инфекционных болезней у детей</p><p>Москва</p></bio><bio xml:lang="en"><p>Chuelov S. B.</p><p>Moscow</p></bio><email xlink:type="simple">chuelovsb@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5914-8427</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Россина</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Rossina</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Россина Анна Львовна - к.м.н., доцент кафедры инфекционных болезней у детей</p><p>Москва</p></bio><bio xml:lang="en"><p>Rossina A. L.</p><p>Moscow</p></bio><email xlink:type="simple">rosann@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Российский национальный исследовательский медицинский университет им. Н. И. Пирогова<country>Россия</country></aff><aff xml:lang="en">Pirogov Russian National Research Medical University Ministry of Health<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>23</day><month>03</month><year>2024</year></pub-date><volume>23</volume><issue>1</issue><fpage>44</fpage><lpage>48</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чуелов С.Б., Россина А.Л., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Чуелов С.Б., Россина А.Л.</copyright-holder><copyright-holder xml:lang="en">Chuelov S.B., Rossina A.L.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://detinf.elpub.ru/jour/article/view/915">https://detinf.elpub.ru/jour/article/view/915</self-uri><abstract><p>Актуальность проблемы спарганоза обусловлена широкой распространенностью данного заболевания в дикой природе, полиморфизмом клинических проявлений и возможностью тяжелых поражений орбит, центральной нервной системы и внутренних органов. Целью работы является обобщение имеющихся в литературе данных об этиологии, эпидемиологии, клинике, диагностике, лечении, профилактике спарганоза. Материалы и методы: проведен обзор отечественной и зарубежной литературы за последние 30 лет, в том числе, Интернет-ресурсов. Результаты. Возбудителями спарганоза являются Spirometra decipiens, Spirometra erinaceieuropaei, Spirometra folium, Spirometra mansoni, а также Sparganum proliferum. Выделяют непролиферативный (периферический, церебральный, спинальный, глазной, висцеральный) и пролиферативный спарганоз. Диагностика осуществляется на основе комплекса клинических, инструментальных, серологических, молекулярно-генетических исследований. Лечение рекомендуется хирургическое: полное удаление спарганов.</p></abstract><trans-abstract xml:lang="en"><p>The urgency of the problem of sparganosis is due to the widespread prevalence of this disease in the wild, polymorphism of clinical manifestations and the possibility of severe damage to the orbits, central nervous system and internal organs. The purpose and result of the work is to summarize the data available in the literature on the etiology, epidemiology, clinical picture, diagnosis, treatment, and prevention of sparganosis. Conclusion. The causative agents of sparganosis are Spirometra decipiens, Spirometra erinaceieuropaei, Spirometra folium, Spirometra mansoni, and Sparganum proliferum. Allocate non-proliferative (peripheral, cerebral, spinal, ocular, visceral) and proliferative sparganosis. Diagnostics is carried out on the basis of a complex of clinical, instrumental, serological, molecular genetic studies. Surgical treatment is recommended: complete removal of the spargans</p></trans-abstract><kwd-group xml:lang="ru"><kwd>спарганоз</kwd><kwd>Spirometra decipiens</kwd><kwd>Spirometra erinaceieuropaei</kwd><kwd>Spirometra folium</kwd><kwd>Spirometra mansoni</kwd><kwd>Sparganum proliferum</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sparganosis</kwd><kwd>Spirometra decipiens</kwd><kwd>Spirometra erinaceieuropaei</kwd><kwd>Spirometra folium</kwd><kwd>Spirometra mansoni</kwd><kwd>Sparganum proliferum</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гаевская А.В. Мир паразитов человека. III. Цестоды и цестодозы пищевого происхождения. Севастополь: ООО «Колорит», 2017:358.</mixed-citation><mixed-citation xml:lang="en">Gaevskaya A.V. The world of human parasites. III. Cestodes and cestodoses of food origin. Sevastopol': OOO «Kolorit», 2017:358. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Kuchta R., Kołodziej-Sobocińska M., Brabec J. et al. Sparganosis (Spirometra) in Europe in the Molecular Era. Clin. Infect. Dis. 2021; 72(5:882—890. doi: 10.1093/cid/ciaa1036</mixed-citation><mixed-citation xml:lang="en">Kuchta R., Kołodziej-Sobocińska M., Brabec J. et al. Sparganosis (Spirometra) in Europe in the Molecular Era. Clin. Infect. Dis. 2021; 72(5:882—890. doi: 10.1093/cid/ciaa1036</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Kuchta R., Scholz T., Brabec J., Wicht B. Diphyllobothrium, Diplogonoporus, and Spirometra. In: Biology of Foodborne Parasites. Section III. Important Foodborne Helminths. Chapter 17, pp.299—326. Publisher CRC Press, Boca Raton, Florida. Еdited by L. Xiao, U. Ryan Y. Feng, 2015.</mixed-citation><mixed-citation xml:lang="en">Kuchta R., Scholz T., Brabec J., Wicht B. Diphyllobothrium, Diplogonoporus, and Spirometra. In: Biology of Foodborne Parasites. Section III. Important Foodborne Helminths. Chapter 17, pp.299—326. Publisher CRC Press, Boca Raton, Florida. Еdited by L. Xiao, U. Ryan Y. Feng, 2015.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">База данных NCBI (National Center for Biotechnology Information) (https://www.ncbi.nlm.nih.gov/taxonomy/)</mixed-citation><mixed-citation xml:lang="en">Database NCBI (National Center for Biotechnology Information)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">База данных UniProt (Universal Protein Resource) ( https://www.uniprot.org/taxonomy/)</mixed-citation><mixed-citation xml:lang="en">Database UniProt (Universal Protein Resource) (https://www.uniprot.org/taxonomy/)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Kikuchi T., Maruyama H. Human proliferative sparganosis update. Parasitol. Int. 2020. 75: 102036. doi: 10.1016/j.parint.2019.102036</mixed-citation><mixed-citation xml:lang="en">Kikuchi T., Maruyama H. Human proliferative sparganosis update. Parasitol.Int. 2020. 75: 102036. doi: 10.1016/j.parint.2019.102036</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Garcia L.S. Diagnostic medical parasitology. 5th ed. Washington, D.C.,ASM Press, 2007.</mixed-citation><mixed-citation xml:lang="en">Garcia L.S. Diagnostic medical parasitology. 5th ed. Washington, D.C.,ASM Press, 2007.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Wiwanitkit V. A review of human sparganosis in Thailand. Int. J. Infect. Dis.2005. 9(6): 312—316. doi: 10.1016/j.ijid.2004.08.003</mixed-citation><mixed-citation xml:lang="en">Wiwanitkit V. A review of human sparganosis in Thailand. Int. J. Infect. Dis.2005. 9(6): 312—316. doi: 10.1016/j.ijid.2004.08.003</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Lu G., Shi D.Z., Lu Y.J. et al. Retrospective epidemiological analysis of sparganosis in mainland China from 1959 to 2012. Epidemiol. Infect. 2014. 142(12):2654—2661. doi: 10.1017/S0950268814000144</mixed-citation><mixed-citation xml:lang="en">Lu G., Shi D.Z., Lu Y.J. et al. Retrospective epidemiological analysis of sparganosis in mainland China from 1959 to 2012. Epidemiol. Infect. 2014. 142(12):2654—2661. doi: 10.1017/S0950268814000144</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Kim J.G., Ahn C.S., Sohn W.M. et al. Human Sparganosis in Korea. J. Korean Med. Sci. 2018. 33(44):e273. doi:10.3346/jkms.2018.33.e273</mixed-citation><mixed-citation xml:lang="en">Kim J.G., Ahn C.S., Sohn W.M. et al. Human Sparganosis in Korea. J. Korean Med. Sci. 2018. 33(44):e273. doi:10.3346/jkms.2018.33.e273</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Muller R. Worms and Human Disease. Second Edition. CABI Publishing, Wallingford, Oxon, UK, 2002.</mixed-citation><mixed-citation xml:lang="en">Muller R. Worms and Human Disease. Second Edition. CABI Publishing, Wallingford, Oxon, UK, 2002.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Lescano A.G., Zunt J. Other cestodes: sparganosis, coenurosis and Taenia crassiceps cysticercosis. Handb. Clin. Neurol. 2013; 114:335—345. doi:10.1016/B978-0-444-53490-3.00027-3</mixed-citation><mixed-citation xml:lang="en">Lescano A.G., Zunt J. Other cestodes: sparganosis, coenurosis and Taenia crassiceps cysticercosis. Handb. Clin. Neurol. 2013; 114:335—345. doi:10.1016/B978-0-444-53490-3.00027-3</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Zoonoses and communicable diseases common to man and animals: parasitoses. 3rd ed. Washington, D.C.: PAHO, 2003.</mixed-citation><mixed-citation xml:lang="en">Zoonoses and communicable diseases common to man and animals: parasitoses. 3rd ed. Washington, D.C.: PAHO, 2003.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Cho J.H., Lee K.B., Yong T.S. et al. Subcutaneous and musculoskeletal sparganosis: Imaging characteristics and pathologic correlation. Skeletal Radiol. 2000. 29:402—408. 10.1007/s002560000206</mixed-citation><mixed-citation xml:lang="en">Cho J.H., Lee K.B., Yong T.S. et al. Subcutaneous and musculoskeletal sparganosis: Imaging characteristics and pathologic correlation. Skeletal Radiol. 2000. 29:402—408. 10.1007/s002560000206</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Koo M., Kim J.H., Kim J.S. et al. Cases and literature review of breast sparganosis. World J. Surg. 2011. 35(3):573—579. doi: 10.1007/s00268-010-0942-1</mixed-citation><mixed-citation xml:lang="en">Koo M., Kim J.H., Kim J.S. et al. Cases and literature review of breast sparganosis. World J. Surg. 2011. 35(3):573—579. doi: 10.1007/s00268-010-0942-1</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Song E.J., Sohn Y.M., Ryu K.N. et al. Breast sparganosis and incidentally detected subcutaneous and intramuscular sparganosis at several sites: case report and literature review. Jpn. J. Radiol. 2015. 33(4):225—228. doi: 10.1007/s11604-015-0405-6</mixed-citation><mixed-citation xml:lang="en">Song E.J., Sohn Y.M., Ryu K.N. et al. Breast sparganosis and incidentally detected subcutaneous and intramuscular sparganosis at several sites: case report and literature review. Jpn. J. Radiol. 2015. 33(4):225—228. doi: 10.1007/s11604-015-0405-6</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Xia Q., Yan J. Diagnosis and surgical management of orbital sparganosis. Eye. 2019. 33:1418—1422. doi.org/10.1038/s41433-019-0427-x</mixed-citation><mixed-citation xml:lang="en">Xia Q., Yan J. Diagnosis and surgical management of orbital sparganosis. Eye. 2019. 33:1418—1422. doi.org/10.1038/s41433-019-0427-x</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Saksirisampant W., Eamudomkarn C., Jeon H.K. et al. Ocular Sparganosis: The First Report of Spirometra ranarum in Thailand. Korean J. Parasitol. 2020. — 58(5):577—581. doi: 10.3347/kjp.2020.58.5.577</mixed-citation><mixed-citation xml:lang="en">Saksirisampant W., Eamudomkarn C., Jeon H.K. et al. Ocular Sparganosis: The First Report of Spirometra ranarum in Thailand. Korean J. Parasitol. 2020. — 58(5):577—581. doi: 10.3347/kjp.2020.58.5.577</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Chang K.H., Chi J.G., Cho S.Y. et al. Cerebral sparganosis: analysis of 34 cases with emphasis on CT features. Neuroradiology. 1992. 34(1):1—8. doi: 10.1007/BF00588423</mixed-citation><mixed-citation xml:lang="en">Chang K.H., Chi J.G., Cho S.Y. et al. Cerebral sparganosis: analysis of 34 cases with emphasis on CT features. Neuroradiology. 1992. 34(1):1—8. doi: 10.1007/BF00588423</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Park J.H., Park Y.S., Kim J.S., Roh S.W. Sparganosis in the lumbar spine: report of two cases and review of the literature. J. Korean Neurosurg. Soc. 2011. 49(4):241—244. doi: 10.3340/jkns.2011.49.4.241</mixed-citation><mixed-citation xml:lang="en">Park J.H., Park Y.S., Kim J.S., Roh S.W. Sparganosis in the lumbar spine: report of two cases and review of the literature. J. Korean Neurosurg. Soc. 2011. 49(4):241—244. doi: 10.3340/jkns.2011.49.4.241</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Song T., Wang W.S., Zhou B.R. et al. CT and MR characteristics of cerebral sparganosis. AJNR Am. J. Neuroradiol. 2007. 28(9):1700—1705. doi:10.3174/ajnr.A0659</mixed-citation><mixed-citation xml:lang="en">Song T., Wang W.S., Zhou B.R. et al. CT and MR characteristics of cerebral sparganosis. AJNR Am. J. Neuroradiol. 2007. 28(9):1700—1705. doi:10.3174/ajnr.A0659</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Gong C., Liao W., Chineah A. et al. Cerebral sparganosis in children: epidemiological, clinical and MR imaging characteristics. BMC Pediatr. 2012. 12:155. https://doi.org/10.1186/1471-2431-12-155</mixed-citation><mixed-citation xml:lang="en">Gong C., Liao W., Chineah A. et al. Cerebral sparganosis in children: epidemiological, clinical and MR imaging characteristics. BMC Pediatr. 2012. 12:155. https://doi.org/10.1186/1471-2431-12-155</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Li Y.X., Ramsahye H., Yin B. et al. Migration: a notable feature of cerebral sparganosis on follow-up MR imaging. AJNR Am. J. Neuroradiol. 2013. 34(2):327—33. doi: 10.3174/ajnr.A3237</mixed-citation><mixed-citation xml:lang="en">Li Y.X., Ramsahye H., Yin B. et al. Migration: a notable feature of cerebral sparganosis on follow-up MR imaging. AJNR Am. J. Neuroradiol. 2013. 34(2):327—33. doi: 10.3174/ajnr.A3237</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Jeon H.K., Park H., Lee D. et al. Human Infections with Spirometra decipiens Plerocercoids Identified by Morphologic and Genetic Analyses in Korea. Korean J. Parasitol. 2015. 53(3):299—305. doi:10.3347/kjp.2015.53.3.299</mixed-citation><mixed-citation xml:lang="en">Jeon H.K., Park H., Lee D. et al. Human Infections with Spirometra decipiens Plerocercoids Identified by Morphologic and Genetic Analyses in Korea. Korean J. Parasitol. 2015. 53(3):299—305. doi:10.3347/kjp.2015.53.3.299</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Chung Y.B., Kong Y., Yang H.J., Cho S.Y. IgG antibody responses in early experimental sparganosis and IgG subclass responses in human sparganosis. Korean J. Parasitol. 2000. 38(3):145—150. doi:10.3347/kjp.2000.38.3.145</mixed-citation><mixed-citation xml:lang="en">Chung Y.B., Kong Y., Yang H.J., Cho S.Y. IgG antibody responses in early experimental sparganosis and IgG subclass responses in human sparganosis. Korean J. Parasitol. 2000. 38(3):145—150. doi:10.3347/kjp.2000.38.3.145</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Hong D., Xie H., Wan H. et al. Efficacy comparison between long-term highdose praziquantel and surgical therapy for cerebral sparganosis: A multicenter retrospective cohort study. PLoS Negl. Trop. Dis. 2018. 12(10): e0006918. doi:10.1371/journal.pntd.0006918</mixed-citation><mixed-citation xml:lang="en">Hong D., Xie H., Wan H. et al. Efficacy comparison between long-term highdose praziquantel and surgical therapy for cerebral sparganosis: A multicenter retrospective cohort study. PLoS Negl. Trop. Dis. 2018. 12(10): e0006918. doi:10.1371/journal.pntd.0006918</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang P., Zou Y., Yu F.X. et al. Follow-up study of high-dose praziquantel therapy for cerebral sparganosis. PLoS Negl. Trop. Dis. 2019. 13(1): e0007018. doi:10.1371/journal.pntd.0007018</mixed-citation><mixed-citation xml:lang="en">Zhang P., Zou Y., Yu F.X. et al. Follow-up study of high-dose praziquantel therapy for cerebral sparganosis. PLoS Negl. Trop. Dis. 2019. 13(1): e0007018. doi:10.1371/journal.pntd.0007018</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
