detinfДЕТСКИЕ ИНФЕКЦИИCHILDREN INFECTIONS2072-81072618-8139Association of Pediatricians and Infection Disease doctors10.22627/2072-8107-2024-23-3-45-54detinf-970Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEW OF THE LITERATUREРедкие инфекции перинатального периодаRare perinatal infectionshttps://orcid.org/0009-0001-0614-9215ФадееваА. А.FadeevaА. А.

Фадеева Анастасия Андреевна, ординатор кафедры госпитальной педиатрии им. академика В.А. Таболина,

Москва.

Moscow.

anastasifade@gmail.comhttps://orcid.org/0000-0001-7305-9036СаркисянЕ. А.SarkisyanH. A.

Саркисян Егине Альбертовна, к.м.н, доцент кафедры госпитальной педиатрии им. академика В.А. Таболина,

Москва.

Moscow.

heghinesarg@gmail.comhttps://orcid.org/0000-0003-2840-7382МолочковаО. В.MolochkovaO. V.

Молочкова Оксана Вадимовна, к.м.н., доцент кафедры инфекционных болезней у детей,

Москва.

Moscow.

ci-journal@mail.ruhttps://orcid.org/0000-0001-9405-7726ЕгороваН. Ю.EgorovaN. Yu.

Егорова Наталья Юрьевна, к.м.н., доцент кафедры инфекционных болезней у детей,

Москва.

Moscow.

a-egoroff@mail.ruhttps://orcid.org/0000-0002-9808-1931КомароваА. А.KomarovaА. А.

Комарова Анна Анатольевна, ординатор кафедры инфекционных болезней у детей,

Москва.

Moscow.

komarova.anna.09@gmail.comhttps://orcid.org/0009-0003-8625-7199МущероваД. М.MushcherovaD. M.

Мущерова Диана Максимовна, студент 6 курса педиатрического факультета,

Москва.

Moscow.

diana.muscherova@mail.ruhttps://orcid.org/0009-0004-6314-1086ХохловаА. П.KhokhlovaA. P.

Хохлова Анастасия Павловна, студент 6 курса педиатрического факультета,

Москва.

Moscow.

nas.hohlova@yandex.ruhttps://orcid.org/0000-0003-1842-4154СаватееваО. И.SavateevaO. I.

Саватеева Ольга Ильинична, ординатор кафедры госпитальной педиатрии им. В.А. Таболина,

Москва.

Moscow.

olgasawa00@gmail.comhttps://orcid.org/0000-0002-9567-6761ШумиловП. В.ShumilovP. V.

Шумилов Петр Валентинович, д.м.н., профессор, заведующий кафедрой госпитальной педиатрии им. академика В.А. Таболина,

Москва.

Moscow.

peter_shumilov@mail.ruФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Минздрава РоссииPirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation2024260920242334554Copyright © Фадеева А.А., Саркисян Е.А., Молочкова О.В., Егорова Н.Ю., Комарова А.А., Мущерова Д.М., Хохлова А.П., Саватеева О.И., Шумилов П.В., 20242024Фадеева А.А., Саркисян Е.А., Молочкова О.В., Егорова Н.Ю., Комарова А.А., Мущерова Д.М., Хохлова А.П., Саватеева О.И., Шумилов П.В.Fadeeva А.А., Sarkisyan H.A., Molochkova O.V., Egorova N.Y., Komarova А.А., Mushcherova D.M., Khokhlova A.P., Savateeva O.I., Shumilov P.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://detinf.elpub.ru/jour/article/view/970

Врожденные вирусные инфекции — одна из актуальных проблем современной неонатологии. Виремия, как одна из стадий инфекционного процесса, обуславливает антенатальное гематогенное инфицирование плода с высоким риском поражения различных органов и систем. Наиболее частыми проявлениями врожденных вирусных инфекций являются: задержка внутриутробного развития (ЗВУР), микро- или макроцефалия, гидроцефалия, гепатоспленомегалия, пневмония, костные поражения, экзантема и гематологические отклонения. Несмотря на неспецифичность клинических проявлений, выявление этиологического фактора нередко является необходимым этапом для определения дальнейшей тактики ведения новорожденного. Материалы и методы: проведен обзор наиболее актуальной отечественной и зарубежной литературы о вирусе лимфоцитарного хориоменингита (ЛХМВ) и вирусе Зика. Результаты: врожденные инфекции, обусловленные ЛХМВ и вирусом Зика, обладают сходными клиническими проявлениями. Лабораторные и инструментальные методы исследования позволяют провести дифференциальную диагностику, определить прогноз и тактику ведения пациента.

Congenital viral infections are one of the pressing issues in modern neonatology. Due to the fact that viremia is a common stage in the infection process, the fetus is at high risk of intrauterine hematogenic infection, which can harm various organs and systems. The most frequently observed manifestations of congential viral infections are: intrauterine growth restriction (IUGR), micro- and macrocephaly, fetal hydrocephalus, hepatosplenomegaly, pneumonia, bone lesions, rash and haematological abnormalities. Even though these clinical manifestations are not specific, identifying the etiological factor is often a necessary step to determine the future management of the newborn. The aim of this paper is to collect and summarize literary data on lymphocytic choriomeningitis virus (LCMV) and Zika virus. Results: congenital infections caused by LCMV and Zika virus share similar clinical features. Laboratory and instrumental diagnostic methods facilitate carrying out the differential diagnosis and establishing prognosis and the best clinical approach to the patient.

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The authors declare that there are no conflicts of interest present.