The Prevalence of Herpes Virus Infections in the Active Phase in Hospitalized Children with Rotavirus Infection
https://doi.org/10.22627/2072-8107-2018-17-4-18-21
Abstract
Under the supervision there were 301 children hospitalized in an infectious hospital with a diagnosis of rotavirus infection. All children were examined for the presence of human herpes virus DNA 4, 5 and type 6 (EBV, CMV, HHV6) in the blood. The majority of hospitalized children with rotavirus infection were under 3 years of age (85.7%). Revealed a high percentage of children of different ages with herpes viral infections in the active phase. In the case of monoinfection, the most frequent active infection was caused by HHV6 type (45.5%). In the case of an associated infectious process, the predominant viruses were EBV and HHV6 (29.3%). Children with active herpes virus who had a rotavirus infection need follow-up monitoring.
Keywords
About the Authors
V. V. KrasnovRussian Federation
Viktor Krasnov, MD, Professor, head of the Department of infectious diseases
Nizhny Novgorod
T. D. Aleksandrova
Russian Federation
T. Aleksandrova, the Department of Infectious Diseases
Nizhny Novgorod
N. E. Senyaginа
Russian Federation
N. Senyagina, PhD, Associate Professor, the Department of Infectious Diseases
Nizhny Novgorod
L. V. Nazarova
Russian Federation
L. Nazarova, PhD, Laboratory Head
Nizhny Novgorod
References
1. Gorelov A.V., Grigorovich M.S. Acute intestinal infections in children: long-term outcomes, their determining factors. Optimization of rehabilitation ways. Moscow-Kirov, 2012: 206. (In Russ.)
2. Vasyunin A.V., Krasnova E.I. Intestinal infections in children. Novosibirsk, 2013: 187. (In Russ.)
3. Baranov A.A., Namazova-Baranova L.S., Tatochenko V.K., Vishneva E.A., Fedoseenko M.V., Selimzyanova L.R., Lobzin Yu.V., Kharit S.M., Bekhtereva M.K., Briko N.I., Mindlina A.Ya., Kudryavtsev V.V., Gorelov A.V., Podkolzin A.T., Kostinov M.P. Rotavirus infection in children is an unsolved problem. Pediatric Pharmacology. 2017; 14(4): 248—257. (In Russ.)
4. Tkhakushinova N.Kh., Gorelov A.V. Repeated acute intestinal infections of rotavirus etiology in children: features of the course, risk factors, developmental conditions and outcomes. Infectious Diseases. 2017. 15(1):29—34. (In Russ.)
5. Krasnov M.V., Akimova V.P., Stekolschikova I.A., Andreeva L.V. Clinical and epidemiological features of rotavirus infection in children. Medical Almanac. 2016. 5(45): 229—231. (In Russ.)
6. Ploskireva A.A. Rotavirus infection in children and its combined forms. Experimental and Clinical Gastroenterology. 2017. 6(142): 26—30. (In Russ.)
7. Molochkova O.V., Kovalev O.B., Rossina A.L., Shamsheva O.V., Korsunsky A.A., Kaschenko O.A., Galeeva E.V., Krylatova N.I., Chuelov S.B., Pylaeva E.Yu., Karaulova V.E. Clinico-etiological characteristics of Acute Intestinal Infections in hospitalized children of Moscow in 2015—2017. Detskie Infektsii=Children's Infections. 2018; 17 (3): 27—33. https://doi.org/10.22627/2072-8107-2018-17-3-27-33
8. . Mazankova L.N., Gorbunov S.G. Diagnosis and treatment of rotavirus infection in young children. Farmateka. 2017. 4(337): 24— 29. (In Russ.)
9. Mikhailova E.V., Levin D.Yu., Karalsky S.A., Karalskaya J.J., Zheleznikov P.A. Norovirus infection in children: clinical and epidemiological characteristics. Infectious Diseases. 2018. 16(1): 40— 43. (In Russ.)
10. Timchenko V.N., Subbotina MD, Kaplina T.A., Bulina O.V., Sukhovetskaya V.F., Khakizimanа Zh.K., Shakmaeva M.A. Clinical and laboratory efficacy of the drug Viferon® in viral lesions of the gastrointestinal tract in children. Pediatrician. 2018. 9(3): 41—48. (In Russ.)
11. Barinsky I.F. Herpes: etiology, diagnosis, treatment. Moscow: Medicine, 1994: 342. (In Russ.)
12. Isakov V.A., S.B. Rybalkin, M.G. Romantsov. Herpes virus infection. St. Petersburg, 2006: 48. (In Russ.)
13. Barkhatovа T.V. Senyaginа N.E. Krasnov V.V. Effect of human herpes virus type 6 on the course of pyelonephritis in children. Detskie Infektsii=Children's Infections. 2014; 13(1): 26—28. (In Russ.)
Review
For citations:
Krasnov V.V., Aleksandrova T.D., Senyaginа N.E., Nazarova L.V. The Prevalence of Herpes Virus Infections in the Active Phase in Hospitalized Children with Rotavirus Infection. CHILDREN INFECTIONS. 2018;17(4):18-21. (In Russ.) https://doi.org/10.22627/2072-8107-2018-17-4-18-21