Optimization of complex treatment of infectious mononucleosis in children
https://doi.org/10.22627/2072-8107-2019-18-2-36-41
Abstract
98 patients from 2 to 12 years old were observed with infectious mononucleosis (IM). Diagnosis was confirmed by the detection of M- and G-antibodies to EBV, CMV, HHV6, PCR DNA these viruses, bacteriological and blood-tests investigations. 58 patients in the complex therapy was given probiotic bifidumbacterin forte 45—90 doses a day (1-st group). The comparison group consisted of 40 patients with IM receiving symptomatic complex therapy and antibiotics (2-nd group). The observations shoved significant decreasing of length of clinical symptoms IM in the 1-st group with comparison of the 2-nd group. The investigation of concentration DNA these viruses (1-st group) demonstrated its rapid decreasing in blood to the second week of mononucleosis. The obtained results allow to recommend bifidumbacterin forte in the complex therapy in children with these infections.
About the Authors
A. G. Bokovoy
Мoscow Government University named after M.V. Lomonosov
Russian Federation
Russian Federation
Alexander Bokovoy - МD, Professor.
Moscow.
M. G. Vershinina
Сentral clinical hospital of Government Russian Federation
Russian Federation
Russian Federation
Moscow.
A. Yu. Medkovа
Мoscow Government University named after M.V. Lomonosov; Сentral clinical hospital of Government Russian Federation
Russian Federation
Russian Federation
Moscow.
I. V. Kovalev
Сentral clinical hospital of Government Russian Federation
Russian Federation
Russian Federation
Moscow.
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Review
For citations:
Bokovoy A.G., Vershinina M.G., Medkovа A.Yu., Kovalev I.V. Optimization of complex treatment of infectious mononucleosis in children. CHILDREN INFECTIONS. 2019;18(2):36-41. (In Russ.) https://doi.org/10.22627/2072-8107-2019-18-2-36-41
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