Clinical observation of Сhronic granulomatous disease in a 6-year-old child
https://doi.org/10.22627/2072-8107-2020-19-4-69-72
Abstract
Chronic granulomatous disease (CGD) is a hereditary disease caused by a genetic defect of violations of oxygen — dependent mechanisms of phagocytosis.
Clinical manifestations of the disease are recurrent bacterial or fungal infections of the skin, hepatic abscesses, pneumonia, osteomyelitis, sepsis, meningitis et al. Most available laboratory method for the diagnosis of CGD is the test of histochemical nitro blue tetrazolium recovery (NBT-test). Allogeneic hematopoietic stem cell transplantation is considered a radical treatment for chronic granulomatous disease.
The article presents a clinical observation of the manifestation of chronic granulomatous disease with an unfavorable outcome in a child aged 6 years.
About the Authors
G. A. Kharchenko
Astrakhan state medical University the Ministry of health Russian Federation
Russian Federation
Russian Federation
Gennady Kharchenko, MD, рrofessor, head of the вepartment of children's infections
Astrakhan
O. G. Kimirilova
Astrakhan state medical University the Ministry of health Russian Federation
Russian Federation
Russian Federation
Olga Kimirilova, PhD, the department of children's infections
Astrakhan
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Review
For citations:
Kharchenko G.A., Kimirilova O.G. Clinical observation of Сhronic granulomatous disease in a 6-year-old child. CHILDREN INFECTIONS. 2020;19(4):69-72. (In Russ.) https://doi.org/10.22627/2072-8107-2020-19-4-69-72
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