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The use in pediatrics of recombinant interferon alfa-2b preparations in the dosage form rectal suppositories: whom? when? which ones?

https://doi.org/10.22627/2072-8107-2021-20-1-45-49

Abstract

The paper presents the indications and main differences of frequently used rectal suppositories containing interferon alpha-2b.The features and differences in the contained excipients are highlighted. A range of diseases in children's practice is presented, in which candles are shown VIFERON®, Kipferon®, Genferon light®

About the Authors

M. S. Savenkova
Russian National Research Medical University. N.I. Pirogov, Ministry of Health of Russia
Russian Federation

MD, Professor of the Department of functional diagnostics



M. P. Savenkov
Russian National Research Medical University. N.I. Pirogov, Ministry of Health of Russia
Russian Federation

 MD, Professor of the Department of functional diagnostics



References

1. Ketlinsky S.A., Simbirtsev A.S. Cytokines. SPb., 2008. (In Russ)

2. Ershov F.I., Narovlyansky A.N. Theoretical and applied aspects of the interferon system: to the 60th anniversary of the discovery of interferons. Voprosy Virusologii. 2018. 63(1): 10—17. (In Russ.)

3. Nesterova I.V. Interferon alpha preparations in clinical practice: when and how. Lechashchiy Vrach. 2017. 9: 66-77. (In Russ.)

4. Khmelevskoy V.I., Provotorov V.Ya., Kiseleva V.V., Devyanin O.A. Alpha interferon in clinical practice. Archive of Internal Medicine. 2014; 5 (19): 34—40. (In Russ.)

5. Narovlyansky A.N., Ershov F.I., Gintsburg A.L. Interferons: Prospects for Research Directions. Immunology. 2013; 3: 168—172. (In Russ.)

6. Sineva T.D. Actual problems of pediatrics: features of the use of drugs in pediatric practice. Zdorov'ye — Osnova Chelovecheskogo Potentsiala: problemy i puti resheniya.2011. 6(1): 317—319. (In Russ.)

7. Malinovskaya V.V. Ontogenesis of the interferon system and the principles of using interferon in practical pediatric practice. Modern aspects of the use of interferons and other immunomodulators. 1990: 70—71. (In Russ.)

8. Malinovskaya V.V., Ershov F.I. Results and prospects for the use of interferon preparations in infectious pediatric practice. Vestnik Akademii meditsinskikh nauk SSSR. 1990; 7: 32-35. (In Russ.)

9. Malinovskaya V.V., Korovina N.A., Parshina O.V., Chebotareva T.A. Guseva T.S. Modern possibilities of using interferons in the complex therapy of acute respiratory infections in children. Lechashchiy Vrach. 2011; 8: 116—119. (In Russ.)

10. Savenkova M.S., Karashtina O.V., Shabat M.B., Kraseva G.N., Abramova N.A., Kraseva T.E. Interferon status and choice of interferon inducers in frequently ill children. Detskie Infektsii=Children's Infections. 2016.15(2):45—51. (In Russ.) doi.org/10.22627/2072-8107-2016-15-2-45-51

11. Chebotareva T.A., Mazankova L.N., Khoperskova A.P., Malinovskaya V.V., Koltsov V.D., Bragina G.S. Recurrent respiratory infections in children and immunorehabilitation programs. Detskie Infektsii=Children's Infections. 2014. 3:61—64. (In Russ.) https://doi.org/10.22627/2072-8107-2014-13-3-61-64

12. Malinovskaya V.V., Timina V.P., Mazankova L.N., Chebotareva T. А. Immunopathogenesis of acute respiratory infections, tactics of rational choice of etiotropic and immunomodulatory therapy in children. Detskie Infektsii=Children's Infections. 2013. 4:14—19. (In Russ.) https://doi.org/10.22627/2072-8107-2013-12-4-14-19

13. Okolysheva N.V., Kisteneva L.B., Vyzhlova E.N., Malinovskaya V.V., et al. The effectiveness of viferon therapy in young children with acute respiratory viral infection. Rossiyskiy Vestnik Perinatologii i Pediatrii=Russian Bulletin of Perinatology and Pediatrics.2015. 2: 78—85. (In Russ.)

14. State register of medicines. https://grls.rosminzdrav.ru (In Russ.)

15. Vasiliev A.N. Evaluation of the effect of antioxidants on the specific antiviral activity of human recombinant interferon alpha-2b against herpes simplex virus in cell culture. Antibiotics and Сhemotherapy. 2010. 7:20—25. (In Russ.)

16. Vasiliev A.N., Deryabin P.G., Galegov G.A. Protvoviral activity of antioxidants and their combinations with human recombinant interferon alpha-2b against avian influenza virus A/H5N1. Cytokines and Inflammation.2011. 10(2):32—36. (In Russ.)

17. Temicheva E.V., Malinovskaya V.V., Manakhova L.S. and other Voprosy Virusologii. 1986.1:12—18. (In Russ.)

18. Temicheva E.V. Interferon status in recurrent genital herpes and correction of its violations: Abstract of the thesis. ... Ph.D. M., 1989. (In Russ.)

19. May J.M., Harrison F.E. Role of vitamin C in the function of the vascular endothelium. Antioxid Redox Signal.2013. 19(17):2068—2083.

20. Paul E. Marik Hydrocortisone, Ascorbic Acid and Thiamine (HAT Therapy) for the Treatment of Sepsis.. Focus on Ascorbic Acid Nutrients. 2018. 10:1762.

21. Lee GY, Han SN. The Role of Vitamin E in Immunity. Nutrients. 2018 Nov 1;10(11):1614.

22. Ruzhentsova T.A., Levitskaya D.S. Treatment of acute respiratory viral infections and influenza in children: results of a meta-analysis. Lechashchiy Vrach. 2020. 3: 52—57. (In Russ.)

23. Zayachnikova T.E., Tolokolnikova E.V., Krasilnikova A.S., Semenenko T.A., Shuvalov A.N., Malinovskaya V.V. Clinical and laboratory efficacy of human recombinant interferon-a-2b in the complex therapy of congenital pneumonia in premature infants. Epidemiologiya i Infektsionnyye Bolezni.2019. 9(4): 58—66. (In Russ.)

24. Zakharova I.N., Torshkhoeva L.B., Zaplatnikov A.L. et al. Modified interferon therapy of acute respiratory infections in young children: pathogenetic rationale and effectiveness. Rossiyskiy Vestnik Perinatologii i Pediatrii=Russian Bulletin of Perinatology and Pediatrics. 2011; 56(3):49—54. (In Russ.)

25. Bokova T.A. Influenza and acute respiratory viral infections in children: the place of interferon preparations in pathogenetic therapy. Lechashchiy Vrach.2017.5: 58—60. (In Russ.)


Review

For citations:


Savenkova M.S., Savenkov M.P. The use in pediatrics of recombinant interferon alfa-2b preparations in the dosage form rectal suppositories: whom? when? which ones? CHILDREN INFECTIONS. 2021;20(1):45-49. (In Russ.) https://doi.org/10.22627/2072-8107-2021-20-1-45-49

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ISSN 2072-8107 (Print)
ISSN 2618-8139 (Online)