The role of TLR-3 in the course and outcomes of rotavirus infection in infants
https://doi.org/10.22627/2072-8107-2022-21-3-5-9
Abstract
It was found that the clinical picture of rotavirus infection in infants with an initially low number of immunocompetent cells expressing TLR-3 does not differ significantly from that of patients with an initially large number of cells expressing TLR-3. When analyzing the treatment, it turned out that antibacterial therapy due to the activation of bacterial microflora was used only in children with an initially low number of immunocompetent cells expressing TLR-3. In the same group of patients, the development of atopic dermatitis and food allergies was noted during catamnestic observation for 6—12 months after rotavirus infection.
About the Authors
S. G. Gorbunov
Russian Medical Academy of Continuig Professional Education of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Moscow
L. N. Mazankova
Russian Medical Academy of Continuig Professional Education of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Moscow
A. N. Os’kin
Russian Medical Academy of Continuig Professional Education of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Moscow
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Review
For citations:
Gorbunov S.G., Mazankova L.N., Os’kin A.N. The role of TLR-3 in the course and outcomes of rotavirus infection in infants. CHILDREN INFECTIONS. 2022;21(3):5-9. (In Russ.) https://doi.org/10.22627/2072-8107-2022-21-3-5-9
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