New coronavirus infection in a child with severe secondary immunodeficiency associated with hematopoietic stem cell transplantation against the background of acute lymphoblastic leukemia
https://doi.org/10.22627/2072-8107-2022-21-3-56-60
Abstract
Children are more likely to have asymptomatic and mild forms of novel coronavirus infection, as well as a more favorable outcome of the disease compared to adult patients. Children account for about 15% of all cases of COVID-19 recorded in the country. There are more and more reports of severe and even fatal cases of a new coronavirus infection in children. The development of severe forms of COVID-19 is typical for children at risk. Of particular interest are special groups of pediatric patients, such as children with immunodeficiencies of various etiologies.
A clinical case of a new coronavirus infection with a fatal outcome in a 10-year-old child with severe secondary immunodeficiency associated with hematopoietic stem cell transplantation against the background of acute lymphoblastic leukemia is presented.
About the Authors
S. M. Bezrodnova
Stavropol State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Stavropol
N. A. Yatsenkо
Regional Clinical Hospital of Infectious Diseases
Russian Federation
Russian Federation
Stavropol
G. M. Sirazhov
Stavropol State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Stavropol
Yu. N. Kashina
Regional Clinical Hospital of Infectious Diseases
Russian Federation
Russian Federation
Stavropol
References
1. Johns Hopkins University Coronavirus Resource Center. COVID-19 Map [Internet]. https://coronavirus.jhu.edu/map.html.
2. Ladhani S.N., Amin-Chowdhury Z., Davies H.G. et al. COVID-19 in children: analysis of the first pandemic peak in England. Arch Dis Child. 2020; 105:1180—1185. http://dx.doi.org/10.1136/archdischild-2020-320042
3. Parri N., Lenge M., Buonsenso D. Children with COVID-19 in pediatric emergency departments in Italy. New Engl. J. Med. 2020, 9; 383(2):187—190. https://doi.org/10.1056/NEJMc2007617
4. Wu Z., McGoogan J.M. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020; 323(13):1239—1242. https://doi.org/10.1001/jama.2020.2648
5. Bi Q., Wu Y., Mei S. et al. Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study. Lancet Infect. Dis. 2020; 20(8):911—919. https://doi.org/10.1016/S1473-3099(20)30287-5
6. Sinha I.P., Harwood R., Semple M.G. et al. COVID-19 infection in children. Lancet Respir Med. 2020; 8(5):446—447. https://doi.org/10.1016/S2213-2600(20)30152-1
7. Meena J., Yadav J., Saini L. et al. Clinical features and outcome of SARS-CoV-2 infection in children: a systematic review and metaanalysis. Indian Pediatr. 2020; 57(9):820—826. https://doi.org/10.1007/s13312-020-1961-0
8. Dorantes-Acosta E., Ávila-Montiel D., Klünder-Klünder M. et al. Survival in pediatric patients with cancer during the COVID-19 pandemic: scoping systematic review. Bol. Med. Hosp. Infant. Mex. 2020; 77(5):234—241. https://doi.org/10.24875/BMHIM.20000174
9. Meena J.P., Gupta A.K., Tanwar P. et al. Clinical presentations and outcomes of children with cancer and COVID19: a systematic review. Pediatr. Blood. Cancer. 2021; 68(6):е29005. https://doi.org/10.1002/pbc.29005
10. The COVID-19 Pandemic: A Rapid Global Response for Children With Cancer From SIOP, COG, SIOP-E, SIOP-PODC, IPSO, PROS, CCI, and St. Jude Global. Pediatr. Blood. Cancer. 2020; 7(3s):1—37. https://doi.org/10.1002/pbc.28409
11. Sadykova D.I., Anokhin V.A., Ziatdinov A.I. Novel coronavirus infection (COVID-19) in children with acute lymphoblastic leukemia. Ros. Vestn. Perinatol. i Pediatr. 2020; 65(5):198—203. (In Russ.) DOI: 10.21508/1027-4065-2020-65-5-198-203
12. Grymova N.N., Khuzina E.A., Furman E.G., Nikonova O.E. A case of a new coronavirus infection in a child with severe secondary immunodeficiency associated with hematopoietic stem cell transplantation. Permskiy Med. Zhurn. 2021. XXXVIII(1):151—160. DOI: 10.17816/pmj381151-160. (In Russ.)
13. Temporary guidelines. Prevention, diagnosis and treatment of novel coronavirus infection (COVID-19). Version 15 (02/22/2022). (In Russ.)
Review
For citations:
Bezrodnova S.M., Yatsenkо N.A., Sirazhov G.M., Kashina Yu.N. New coronavirus infection in a child with severe secondary immunodeficiency associated with hematopoietic stem cell transplantation against the background of acute lymphoblastic leukemia. CHILDREN INFECTIONS. 2022;21(3):56-60. (In Russ.) https://doi.org/10.22627/2072-8107-2022-21-3-56-60
Views:
373
Email this article 