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BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDREN

https://doi.org/10.22627/2072-8107-2015-14-1-3-8

Abstract

80 patients were observed with infectious mononucleosis (IM) from 2 to 12 years. Diagnosis was confirmed by the definition of M- and G-antibodies to EBV, CMV, HHV6, PCR DNA these viruses, bacteriological and blood-tests investigations. 40 patients was given bifidumbacterin forte 45—90 doses a day and cycloferon 8 mg/kg/weight a day(1-st group). The comparison group consisted of 40 patients with IM receiving symptomatic therapy and antibiotics (2-nd group). The observations shoved significant decreasing of length of clinical symptoms IM in the 1-st group with comparison of the 2-nd group. The obtained results allow to recommend bifidumbacterin forte and cycloferon in the complex therapy in children with infectious mononucleosis.

About the Authors

A. G. Bokovoy
Сentral Clinical Hospital of Government Russian Federation, Moskow
Russian Federation
DMS, Professor, Сentral clinical hospital of Government Russian Federation, Moskow; (495) 414-03-44


I. V. Kovalev
Сentral Clinical Hospital of Government Russian Federation, Moskow
Russian Federation


L. F. Makkaveeva
Сentral Clinical Hospital of Government Russian Federation, Moskow
Russian Federation


O. A. Volodina
Сentral Clinical Hospital of Government Russian Federation, Moskow
Russian Federation


A. A. Komarov
Сentral Clinical Hospital of Government Russian Federation, Moskow
Russian Federation


A. Yu. Medkova
Сentral Clinical Hospital of Government Russian Federation, Moskow
Russian Federation


N. B. Tanina
Сentral Clinical Hospital of Government Russian Federation, Moskow
Russian Federation


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Review

For citations:


Bokovoy A.G., Kovalev I.V., Makkaveeva L.F., Volodina O.A., Komarov A.A., Medkova A.Yu., Tanina N.B. BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDREN. CHILDREN INFECTIONS. 2015;14(1):30-35. (In Russ.) https://doi.org/10.22627/2072-8107-2015-14-1-3-8

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ISSN 2072-8107 (Print)
ISSN 2618-8139 (Online)