Neonatal disseminated listeriosis in a premature infant

Pregnant women and newborn infants are at risk of developing severe listeriosis infection. The time of development and the character of the clinical picture of neonatal listeriosis depend on the timing and mechanism of infection of the foetus. Intrauterine infection with this pathogen is one of the leading factors in the development of sepsis and meningitis in the neonatal period. Early laboratory diagnosis and prompt administration of antibiotic therapy are crucial to improve prognosis and reduce mortality in children.

The aim of the work is to demonstrate the tactics of management of a premature infant with severe course of early neonatal listeriosis and favourable outcome according to the results of catamnestic observation.

Materials and methods: The medical records of a child who was under inpatient treatment in a children's multidisciplinary hospital in January—February 2025 due to laboratory-confirmed neonatal disseminated listeriosis were analysed; the outcome of this patient was assessed based on the result of a second planned hospitalisation in April 2025; the world medical literature on neonatal listeriosis was studied using search engines and databases elibrary, PubMed, Google Scholar, Scopus.

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