DIAGNOSTIC VALUE OF CLINICAL AND LABORATORY IMMUNOLOGICAL SIGNS OF INFECTIOUS MONONUCLEOSIS
https://doi.org/10.22627/2072-8107-2013-12-3-51-55
Abstract
For evaluation of importance of each of the leading clinical and laboratory signs of infectious mononucleosis the authors conducted a statistical analysis of the data from 280 patients aging from 10 months to 34 years of age. The analysis was carried out with the use of nonparametric statistical method analysis (ranking analysis of variance and concordance by M. Kendall). Three basic clinic pathogenetic syndromes (lymphoproliferative — tonsillar, lymphoproliferative — parenchymal, lymphostasis ectodermal). Characteristics of laboratory syndrome of immune imbalance are given. An algorithm for the diagnosis of infectious mononucleosis with the inclusion of clinical, laboratory, instrumental, immunological studies is suggested.
About the Authors
I. P. BaranovaRussian Federation
D. Yu. Kurmaevа
Russian Federation
O. N. Lesina
Russian Federation
References
1. Годовая Форма № 2 Федерального государственного статистического наблюдения «Сведения об инфекционных и паразитарных заболеваниях», 2001—2011 г г., номер строки 74.
2. Лобзин Ю.В. Инфекционные болезни. — «Феникс», 2007. — 543 с.
3. Li Z.Y., Lou J.G., Chen J. Analysis of primary symptoms and disease spectrum in Epstein-Barr virus infected children // Zhonghua Er Ke Za Zhi.— 2004. — 42 : 1 : 20—22.
4. Epstein-Barr virus-associated infectious mononucleosis in Chinese children / C.W. Chan, A.K. Chiang, K.H. Chan, A.S. Lau // The Pediatric Infectious Disease Journal. — Baltimore, Md. : Williams & Wilkins, 2003. — V. 22, № 11. — P. 974—978.
5. Thracker E.L., Mirzaei F., Ascherio A. Infectious mononucleosis and risk for multiple sclerosis: a metaanalysis // Ann. Neurol. — 2006. — V. 59. — № 3. — P. 499—503.
6. Баранова И.П. Клинические особенности инфекционного мононуклеоза в зависимости от возраста и этиологии заболевания / И.П. Баранова, Д.Ю. Курмаева, О.Н. Лесина // Детские инфекции. — 2010. — Т 9. — № 4. — С. 25—28.
Review
For citations:
Baranova I.P., Kurmaevа D.Yu., Lesina O.N. DIAGNOSTIC VALUE OF CLINICAL AND LABORATORY IMMUNOLOGICAL SIGNS OF INFECTIOUS MONONUCLEOSIS. CHILDREN INFECTIONS. 2013;12(3):51-55. (In Russ.) https://doi.org/10.22627/2072-8107-2013-12-3-51-55