DOMESTIC SPECTRUM OF ANTIVIRAL DRUG — UMIFENOVIR AS ETIOTROPIC THERAPY OF INFLUENZA
https://doi.org/10.22627/2072-8107-2016-15-3-25-30
Abstract
In this article are presented the results of comparative observation of the effectiveness of the inclusion in the complex therapy of 203 hospitalized children aged 2 years and older with influenza А(Н1N1)pdm09 domestic antiviral drug — Umifenovir (Arbidol) that occurred during the epidemic seasons 2009—2013 and 2015—2016 in terms of observational clinical studies. It is shown that this drug, possessing a wide spectrum of antiviral activity, including against Oseltamivir — and Zanamivir-resistant influenza virus strains, antioxidant activity and low toxicity (Code ATX Ј05АХ13), can be successfully used in the treatment of infants with influenza А(Н1N1)pdm09.
About the Authors
L. V. Osidak
Research Institute of Influenza of The Ministry of Health of the Russian Federation, St. Peterburg
Russian Federation
Russian Federation
Osidak Ludmila — DMS, professor, senior researcher of department of respiratory infections in children.
St. Petersburg; +7(812) 499-15-40; Lvosidak@mail.ru
O. I. Afanasyeva
Research Institute of Influenza of The Ministry of Health of the Russian Federation, St. Peterburg
Russian Federation
Russian Federation
E. G. Golovacheva
Research Institute of Influenza of The Ministry of Health of the Russian Federation, St. Peterburg
Russian Federation
Russian Federation
E. A. Dondurey
Research Institute of Influenza of The Ministry of Health of the Russian Federation, St. Peterburg
Russian Federation
Russian Federation
V. V. Gonchar
Research Institute of Influenza of The Ministry of Health of the Russian Federation, St. Peterburg
Russian Federation
Russian Federation
V. S. Afanasyeva
Research Institute of Influenza of The Ministry of Health of the Russian Federation, St. Peterburg
Russian Federation
Russian Federation
V. F. Suhovetskaya
Research Institute of Influenza of The Ministry of Health of the Russian Federation, St. Peterburg
Russian Federation
Russian Federation
E. V. Obraztsova
Research Institute of Influenza of The Ministry of Health of the Russian Federation, St. Peterburg
Russian Federation
Russian Federation
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Review
For citations:
Osidak L.V., Afanasyeva O.I., Golovacheva E.G., Dondurey E.A., Gonchar V.V., Afanasyeva V.S., Suhovetskaya V.F., Obraztsova E.V. DOMESTIC SPECTRUM OF ANTIVIRAL DRUG — UMIFENOVIR AS ETIOTROPIC THERAPY OF INFLUENZA. CHILDREN INFECTIONS. 2016;15(3):25-30. (In Russ.) https://doi.org/10.22627/2072-8107-2016-15-3-25-30
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