EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN»
https://doi.org/10.22627/2072-8107-2017-16-4-25-29
Abstract
A comparative study of the state of health of 110 women with allergopathology at the stage of pregnancy and their newborn children, with an assessment of the influence of factors burdening fetal fetal development and contributing to the implementation of allergopathology in the first months of life.
Trigger factors of disturbances in the formation of the intestinal microbiota, immune system and congenital decrease in the resistance of the child's organism — gestosis (c2 = 5.2, p = 0.022), Feto-placental insufficiency (c2 = 6.2, p = 0.012), chronic intrauterine fetal hypoxia (c2 = 5.7, p = 0.017), due to the presence in a woman with an allergic disease of combined somatic pathology and pathology of the genitals, malnutrition and microecological status.
Such women should be classified as a high-risk group for intrauterine fetal sensitization and taken from the first days of pregnancy for primary prevention of allergopathology already at the stage of intrauterine development of the fetus.
About the Authors
L. A. Lityaeva
Orenburg State Medical University, Orenburg
Russian Federation
MD, professor of department of epidemiology and infectious diseases
Russian Federation
MD, professor of department of epidemiology and infectious diseases
S. Y. Nosyreva
Orenburg State Medical University, Orenburg
Russian Federation
assistent of department of epidemiology and infectious diseases
Russian Federation
assistent of department of epidemiology and infectious diseases
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Review
For citations:
Lityaeva L.A., Nosyreva S.Y. EPIGENETIC RISK FACTORS OF FETAL SENSITIZATION TO ALLERGENS IN THE SYSTEM «MOTHER-FETUS-NEWBORN». CHILDREN INFECTIONS. 2017;16(4):25-29. (In Russ.) https://doi.org/10.22627/2072-8107-2017-16-4-25-29
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