FEATURES OF ELEMENTAL COMPOSITION IN SCHOOLCHILD WITH ASCARIASIS
https://doi.org/10.22627/2072-8107-2018-17-1-27-33
Abstract
Objective: to study the features of elemental composition in schoolchildren with ascariasis and to compare the revealed features with clinical manifestations of invasion.
Materials and methods: 43 children (7 — 18 years) with ascariasis (diagnostics was carried out by the method of thick smear according to Kato two times with an interval of 3 days and the method of flotation according to Kalantaryan): I subgroup — children of primary school age — 15 people, II subgroup — children of senior school age — 28 people. The control group was 32 relatively healthy schoolchildren. It was determined of 19 chemical elements (Ca, Zn, K, I, Cu, Se, Fe, Mn, Cr, S, Br, Cl, Co, Ni, Mo, Sr, Ba, Pb, Cd) in children's hair was determined.
Results: Low content of Zn, Cu, I, Se, Fe and Se, Br, Co, Ni, as well as increase of toxic Pb and Cd in the hair of junior schoolchildren with ascariasis is established. The invaders of high school students have a significantly lowered level of Ca, Zn, Cu, Fe and Br, Ni, Mo, as well as an elevated level of Ba, Pb, Cd.
Conclusions: Imbalance of micro- and macroelements in the intestinal stage of ascariasis in children is an important pathogenetic link in the formation of the main clinical syndromes in children. Replenishment of microelement imbalance at the stage of treatment and rehabilitation of children with ascariasis is pathogenetically grounded and promotes the speedy restoration of all disturbed functions of the macroorganism.
About the Author
I. A. LokhmatovaRussian Federation
Irina Lokhmatova, post-graduate student of pediatrics department with children's infections.
Lugansk.
References
1. Soil-transmitted helminthiases; eliminating soil-transmitted helminthiases as a public health problem in children: progress report 2001— 2010 and strategic plan 2011—2020. Geneva: World Health Organization. 2012 (http://apps.who.int/iris/bitstream/10665/ 44804/1/9789241503129_eng.pdf, accessed 23 January 2017).
2. Soil-transmitted helminthiases: number of children treated in 2011. Wkly Epidemiol Rec. 2013. 88(14):145—52. http://www.who.int/wer/2013/wer8814.pdf?ua = 1, accessed 23 January 2017.
3. Deworming of school-age children [Text]: reference book for managers of helminth programs. 2 nd ed, Geneva:WHO. 2012:75. (In Russ.)
4. Khalafli Kh.N. Influence of intestinal parasitosis on the health of children. Fundamental'nye Issledovaniya=Fundamental Research. 2013;9(1):156—162. (In Russ.)
5. Helminth infections transmitted through the soil. Information Bulletin № 366, WHO. May 2014. (In Russ.)
6. Ezhov M.N., Davidyants V.A. The state of struggle and prevention of geological melt disorders in the countries of the WHO European Region. Tekhnicheskiy Raport=Technical Report. Copenhagen: WHO Regional Office for Europe. 2013. (In Russ.)
7. Mochalova A.A., Ershova I.B. A look at the problem of helminthiases and parasitosis at the present stage. Aktual'naya Infektologiya=Actual Infectology. 2014;3(2):61—67. (In Russ.)
8. Sokolova N.A., Savina M.I., Karyan G.L., Mukhina Yu.G. Change in the concentration of essential trace elements in the blood plasma in children with chronic diseases of the gastrointestinal tract, having a different body weight. Klinicheskaya Laboratornaya Diagnostika=Clinical Laboratory Diagnostics. 2012;6:12—15. (In Russ.)
9. Mochalova A.A. Clinico-pathogenetic significance of metabolic disorders of microelements in parasitosis in school-age children. Aktual'naya Infektologiya=Actual Infectology. 2014;2(1):45—47. (In Russ.)
10. Pechkurov D.V., Tyazheva A.A. Glistovye infestations in children: clinical significance, diagnosis and treatment. Russkiy Meditsinskiy Zhurnal=Russian Medical Journal. 2014;22(3):242—246. (In Russ.)
11. Krivopustov S.P. [et al.] Helminthiases in clinical pediatrics: diagnosis, therapy, prevention. Zdorov'e Rebenka=Child's Health. 2011;4:31—35. (In Russ.)
12. Skal'nyy A.V., Sal'nikova E.V., Kudryavtseva E.A., Kustova A.S. Accumulation of heavy metals and microelements in the hair of the population of the Orenburg region. Mikroelementy v Meditsine=Microelements in Medicine. 2012;13(4):42—45. (In Russ.)
13. Detkov V.Yu., Skal'nyy A.V., Lomakin Yu.V. The content of essential microelements in the hair of children living in St. Petersburg. Mikroelementy v Meditsine=Microelements in Medicine. 2012; 13(3):41— 44. (In Russ.)
14. Zaynullin V.G., Bodnar' I.S., Kondratenok B.M. Features of the accumulation of chemical elements in the hair of the children of the Republic of Komi. Izvestiya Komi nauchnogo tsentra UrO RAN. Biologicheskie nauki=Proceedings of the Komi Scientific Center of the UrB RAS. Biological Sciences. 2014;18(2):26—31. (In Russ.)
Review
For citations:
Lokhmatova I.A. FEATURES OF ELEMENTAL COMPOSITION IN SCHOOLCHILD WITH ASCARIASIS. CHILDREN INFECTIONS. 2018;17(1):27-33. (In Russ.) https://doi.org/10.22627/2072-8107-2018-17-1-27-33