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THE CHOICE OF DRUGS FOR THE TREATMENT OF INFECTIOUS DISEASES IN CHILDREN WITH DRUG ALLERGY

https://doi.org/10.22627/2072-8107-2018-17-2-40-44

Abstract

The article presents the results of clinical observation of 104 children hospitalized in the infectious department and having manifestations of allergies to drugs (medicines) at the prehospital stage or in the hospital. The frequency of allergic reactions to medicines in children with infectious diseases, their characteristics, as well as approaches to the choice of drugs for treatment, as manifestations of allergies, and the underlying disease in children with drug allergies are estimated. It has been shown that antibacterial drugs are a frequent cause of skin allergic reactions in patients with lacunar angina and infectious mononucleosis. In case of allergy to beta-lactams, macrolides and lincosamides serve as an alternative in most cases. As a drug of choice for fighting fever in patients with an acute allergic reaction to drugs, ibuprofen may be recommended, possibly using paracetamol, metamizole sodium.

About the Authors

E. B. Pavlova
St. Petersburg State Pediatric Medical University of the Ministry of Health of Russia
Russian Federation

Elena Pavlova, Ph.D., Associate Professor of the Department of Pharmacology with the Course of Clinical Pharmacology and Pharmacoeconomics 

St. Petersburg

 



V. N. Timchenko
St. Petersburg State Pediatric Medical University of the Ministry of Health of Russia
Russian Federation
Vladimir Timchenko, Professor, MD, Head of the Department of Infectious Diseases in Children, St. Petersburg State Pediatric Medical University, Chief Infectious Diseases Specialist for Children of the Health Committee of the Government of St. Petersburg


N. V. Pavlova
St. Petersburg State Pediatric Medical University of the Ministry of Health of Russia
Russian Federation

Natalia Pavlova, PhD, Associate Professor of the Department of Infectious Diseases in Children

St. Petersburg



S. L. Bannova
St. Petersburg State Pediatric Medical University of the Ministry of Health of Russia
Russian Federation

Svetlana Bannova, PhD, Associate Professor of the Department of Infectious Diseases in Children 

St. Petersburg




A. V. Fedorovа
St. Petersburg State Pediatric Medical University of the Ministry of Health of Russia
Russian Federation

Anna Fedorova, Associate Professor of the Department of Infectious Diseases in Children 

St. Petersburg



O. V. Bulinа
St. Petersburg State Pediatric Medical University of the Ministry of Health of Russia
Russian Federation

Oksana Bulina, PhD, Associate Professor of the Department of Rehabilitation

St. Petersburg



J. K. Khakizimana
St. Petersburg State Pediatric Medical University of the Ministry of Health of Russia
Russian Federation

Jean-Claude Hakizimana, full-time post-graduate student of the Department of Infectious Diseases in Children

St. Petersburg



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Review

For citations:


Pavlova E.B., Timchenko V.N., Pavlova N.V., Bannova S.L., Fedorovа A.V., Bulinа O.V., Khakizimana J.K. THE CHOICE OF DRUGS FOR THE TREATMENT OF INFECTIOUS DISEASES IN CHILDREN WITH DRUG ALLERGY. CHILDREN INFECTIONS. 2018;17(2):40-44. (In Russ.) https://doi.org/10.22627/2072-8107-2018-17-2-40-44

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ISSN 2072-8107 (Print)
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