Clinical and epidemiological features of the Measles in children of the Astrakhan region
https://doi.org/10.22627/2072-8107-2019-18-3-31-36
Abstract
According to the Rospotrebnadzor of the Russian Federation for the first quarter of 2019 were registered 872 cases of measles, which indicates a tense epidemic situation for this pathology.
Objective: to establish clinical and epidemiological features of measles in children depending on age in the Astrakhan region for the period from January 2013 to June 2019.
Research methods: the analysis of 370 cases of measles in children aged 3 months to 17 years, confirmed by enzyme immunoassay (ELISA).
The results of the study: in the age structure of the incidence of measles in the Astrakhan region prevail unvaccinated children aged 2—3 years, and less than 1 year, not subject to vaccination against measles. The main reasons for the lack of vaccinations in children with measles are: medical taps. The incidence of vaccinated children against measles can be a consequence of violations in the organization of vaccination work. The causes of the presence of measles foci with the spread of infection are nosocomial outbreaks, measles drifts in organized groups, as a result of late detection and isolation of patients. Measles in children of different age groups, both vaccinated and unvaccinated proceeded typically with a predominance of moderate forms. The symptom of Filatov-Koplik remains the main sign of the diagnosis of measles in the catarrhal period of the disease, the gradual appearance of a spotty-papular rash in combination with catarrhal syndrome — in the period of rash, and pigmentation is a retrospective sign of the survive infection.
About the Authors
G. A. Kharchenko
Astrakhan State Medical University
Russian Federation
MD, Рrofessor, head of the department of children's infections
Russian Federation
MD, Рrofessor, head of the department of children's infections
O. G. Kimirilova
Astrakhan State Medical University
Russian Federation
Russian Federation
References
1. Цвиркун О.В., Тихонова Н.Т. Аналитический обзор ситуации с коревой инфекцией в России и Европейском регионе ВОЗ. Эпидемиология и вакцинопрофилактика. 2009; 9(46):12—16. Cvirkun O.V., Tihonova N.T. Analytical review of the situation with measles infection in Russia and the European Region of WHO. Еpidemiologiа i Vakcinoprofilaktika=Epidemiology and Vaccine Prevention. 2009; 9(46):12—16. (in Russ.) https://doi.org/10.31631/2073-3046-2009-9-46-12-16
2. Корь. Информационный бюллетень ВОЗ. 2017. Mediacentre. Measles. Fact sheet. (In Russ). Доступно по: http://www.who.int/mediacentre/factsheets/fs286/ru/
3. Силенова О.В. Особенности вакцинопрофилактики контактных в очагах заболеваемости корью. Санэпидконтроль. Охрана труда. 2015; 4:1—13. Silenova O.V. Peculiarities of vaccine prophylaxis of contact in measles focus. Sanjepidkontrol'. Ohranatruda. 2015; 4:1—13. (in Russ.)
4. Артемова И.В., Куличенко Т.В. Эпидемия кори. Реальна ли угроза? Вопросы современной педиатрии. 2017; 16(5):358— 361. Artemova I.V., Kulichenko T.V. The epidemic of measles. Is the threat real? Voprosy Sovremennoj Pediatrii = The issues of modern pediatrics. 2017; 16(5):358-361. (in Russ.) https://doi.org/10.15690/vsp.v16i5.1799
5. Липатов Д. А. Анализ заболеваемости корью в Российской Федерации в 2016 году и основные направления деятельности по ее профилактике. Мед. Статистика и оргметодработа в учреждениях здравоохранения. 2017; 9:21—25. Lipatov D.A. Analysis of measles incidence in the Russian Federation in 2016 and the main activities for its prevention. Med. Statistika i Orgmetodrabota v Uchrezhdeniyakh Zdravookhraneniya. 2017; 9:21—25. (in Russ.)
6. Тихонова Н.Т., Герасимова А.Г., Цвиркун О.В., Ежлова Е.Б., Шульга С.В., Мамаева Т.А., Тураева Н.В. Причины роста заболеваемости корью в России в период элиминации инфекции. Педиатрия. 2013; 92(1):9—14. Tikhonovа N.T., Gerasimovа A.G., Tsvirkun O.V., Ezhova E.B., Shulga S.V., Mamaeva T.A., Turaeva N.V. Reasons for the rise in the incidence of measles in Russia in the period of elimination of the infection. Pediatriya = Рediatrics. 2013; 92(1):9—14. (in Russ.)
7. Алешкин В.А., Тихонова Н.Т., Герасимова А.Г. Проблемы на пути достижения элиминации кори в Российской Федерации. Журнал микробиологии, эпидемиологии и иммунобиологии. 2016; 5:29—34. Aleshkin V.A., Tikhonova N.T., Gerasimova A.G. Problems on the way to achieve elimination of measles in the Russian Federation. Zhurnal Мikrobiologii Еpidemiologii i Immunobiologii=Journal of Microbiology, Epidemiology and Immunobiology. 2016; 5:29— 34. (in Russ.)
8. Levin A., Burgess C., Garrison L.P. Global eradication of measles: an epidemiologic and economic evaluation. The Journal of Infectious Diseases. 2011; 204:98—106.
9. Мазанкова Л.Н., Беляева Н.М., Горбунов С.Г., Нестерина И.Ф. Корь у детей и взрослых на этапе элиминации. Москва: МЕДпрессинформ, 2017:69. Mazankova L.N., Belyaeva N.M., Gorbunov S.G., Nesterina I.F. Measles in children and adults at the stage of elimination. Moscow: Medpress-inform, 2017:69. (in Russ)
10. Иванова И.А., Понежева Ж.Б., Козлова М.С., Вдовина Е.Т., Цветкова Н.А. Особенности течения кори у взрослых. Лечащий врач. 2018; 11: 36—39. Ivanova I.A., Ponezheva Zh.B., Kozlova M.S., Vdovina E.T., Tsvetkova N.A. Features of the course of measles in adults. Lechashhij Vrach. 2018; 11: 36—39. (in Russ)
11. Приказ Минздрава РФ от 21.03.2003г. №117. «О реализации Программы ликвидации кори в Российской Федерации к 2010 году». Order of the Ministry of Health of the Russian Federation of 21.03.2003. №117. On the implementation of the Measles Eradication Program in the Russian Federation by 2010. http://docs.cntd.ru/document/901859871
12. Health Organization. Meeting of the Strategic Advisory Group of Experts on Immunization, November 2010-summary, conclusions, recommendation. WklyEpidemiol Rec. 2011; 86: 1—16.
13. Сhristi A.S., Gay A. The measles initiative: moving toward measles e adication. The Journal of Infectious Diseases., Oxford University Press. 2011; 204:14—17.
14. Fiebelkorn A.P., Seward J.F., Orenstein W.A. A global perspective of vaccination of healthcare personnel against measles: Systematic review. Vaccine. 2014. 4 32(38): 4823—4839.
15. Moss W.J., Griffin D.E. Measles. Lancet. 2012; 14(379):153— 164.
16. Тимченко В.Н., Каплина Т.А. Бунина О.В., Леонтьева О.А., Хакизимана Е.В., Тимофеева Е.В. Актуальные проблемы коревой инфекции. Педиатр. 2017; 3(8):120 — 129. Timchenko V.N., Kaplina T.A. Bunina O.V., Leont'eva O.A., Hakizimana E.V. Timofeeva E.V. Current problems of measles infection. Pediatr. 2017; 3(8):120—129. (in Russ.)
17. Бочаров И.И., Костиков М.П., Новиков С.В., Шмитко А.Д., Обидина А.А., Цивцивадзе Е.Б. Трансплацентарные антитела к вирусу кори у новорожденных при различном течении беременности у их матерей. Российский вестник акушера и гинеколога. 2014; 14(2):14—18. Bocharov I.I., Kostikov M.P., Novikov S.V., Shmitko A.D., Obidina A.A., Tsivtsivadze E.B. Transplacental antibodies to measles virus in newborns with different course of pregnancy in their mothers. Rossijskij Vestnik Akushera i Ginekologa=Russian Bulletin of the Obstetrician and Gynecologist. 2014; 14(2):14—18. (in Russ.)
18. Тихонова Н.Т., Цвиркун О.В., Герасимова А.Г., Басов А.А., Фролов Р.А., Ежлова Е.Б., Мельникова А.А., Ваталина А.А., Иванников М.Ю., Мельник Т.Н., Захарян А.И. Состояние специфического иммунитета к вирусам кори и краснухи у новорожденных и их матерей. Эпидемиология и вакцинопрофилактика. 2017; 16(6):14 — 20. Tikhonova N.T., Tsvirkun O.V., Gerasimova A.G., Basov A.A., Frolov R.A., Ezhlova E.B., Melnikova A.A., Vatalina A.A., IvannikovM.Yu., Melnik T.N., Zakharyan A.I. The state of specific immunity to measles and rubella viruses in newborns and their mothers. Еpidemiologija i Vakcinoprofilaktika=Epidemiology and Vaccine Prevention. 2017; 16(6): 14—20. (in Russ.) https://doi.org/10.31631/2073-3046-2017-16-6
Review
For citations:
Kharchenko G.A., Kimirilova O.G. Clinical and epidemiological features of the Measles in children of the Astrakhan region. CHILDREN INFECTIONS. 2019;18(3):31-36. (In Russ.) https://doi.org/10.22627/2072-8107-2019-18-3-31-36
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