THE RESULTS OF STUDY OF THE LEVELS OF SPECIFIC ANTIBODIES TO THE COMBINED INJECTION VACCINES AGAINST INFLUENZA, MEASLES, RUBELLA AND MUMPS AND DT IN CHILDREN WITH CHRONIC PHYSICAL ILLNESS
https://doi.org/10.22627/2072-8107-2014-13-3-29-35
Abstract
The levels of antibodies to the separate and combined administration of the vaccine plus Grippol® Plus and vaccines against measles, mumps and/or rubella, diphtheria and tetanus (DT) in children with chronic medical illnesses, including HIV and organic CNS. Revealed that at low reactogenicity and safety of the vaccine Grippol® Plus, concomitant vaccination does not affect the dynamics of the synthesis (seroprotection, seroconversion), diphtheria, mumps, and rubella antibodies, however, reduces the synthesis of measles antibodies. When combined administration of DT and mumps-measles vaccines + Grippol® Plus suppressed antibody response to a strain of influenza virus A/H3N2.
About the Authors
S. M. Haritе
Scientific and Research Institute of Сhildren’s Infections of FMBA of Russia, Saint-Petersburg;
State Pediatric Medical University of Russia, Saint-Petersburg
Russian Federation
DMC, Professor
Russian Federation
DMC, Professor
A. A. Ruleva
Scientific and Research Institute of Сhildren’s Infections of FMBA of Russia, Saint-Petersburg
Russian Federation
Russian Federation
O. V. Goleva
Scientific and Research Institute of Сhildren’s Infections of FMBA of Russia, Saint-Petersburg
Russian Federation
Russian Federation
O. S. Kalinogorskaya
Scientific and Research Institute of Сhildren’s Infections of FMBA of Russia, Saint-Petersburg
Russian Federation
Russian Federation
V. A. Apryatina
Institute of Immunology FMBA of Russia, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Haritе S.M., Ruleva A.A., Goleva O.V., Kalinogorskaya O.S., Apryatina V.A. THE RESULTS OF STUDY OF THE LEVELS OF SPECIFIC ANTIBODIES TO THE COMBINED INJECTION VACCINES AGAINST INFLUENZA, MEASLES, RUBELLA AND MUMPS AND DT IN CHILDREN WITH CHRONIC PHYSICAL ILLNESS. CHILDREN INFECTIONS. 2014;13(3):29-35. (In Russ.) https://doi.org/10.22627/2072-8107-2014-13-3-29-35
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