Features of metapneumovirus and bocavirus infections in children
https://doi.org/10.22627/2072-8107-2020-19-3-12-14
Abstract
Objective: to study the epidemiological and clinical and laboratory features of metapneumovirus (HMPV) and bokavirus infections (HBoV) in children.
Materials and methods. We examined 772 children aged 1 month to 14 years, who were being treated for acute respiratory viral infections at the Kirov infectious diseases clinical hospital in 201 6—201 9. Diagnostics was performed by PCR in nasopharyngeal smears.
Results. Among patients with a confirmed diagnosis, 53 (6.9%) had metapneumovirus infection, and 76 (9.8%) had bokavirus infection. Both groups were dominated by boys. HMPV was more often registered among children from one to three years of age, HBoV — in patients of the first year of life. Mixed infection was more common with HBoV in children of the first three years of life. These infections are characterized by damage to both the upper and lower respiratory tracts with the development of obstruction syndrome, which was more often observed in HBoV. Pneumonia was developed in half of the cases in both groups. Gastroenteritis was registered in patients with HMPV in 1 9% of cases, and in patients with HBoV in 1 3% of cases.
About the Authors
T. I. Kaluzhskich
Kirov state medical University
Russian Federation
Russian Federation
Tatiana Kaluzhskich
N. A. Savinykh
Kirov state medical University
Russian Federation
Russian Federation
Nataliia Savinykh
M. V. Savinykh
Kirov state medical University
Russian Federation
Russian Federation
Maksim Savinykh
E. O. Utenkova
Kirov state medical University
Russian Federation
Russian Federation
ElenaUtenkova
References
1. Shamsheva O. V. Flu and SARS in children. M.: GEOTAR-Media, 2018: 1 12. (in Russ.)
2. Hamelin M.E., Abed Y., Boiving G. Human metapneumovirus: a new player among respiratory viruses. Clin. Infect. Dis., 2004, 38:983 — 990.
3. Allander T, Jartti T, Gupta S et al. Human bocavirusand acute wheezing in children. Clin. Infect. Dis., 2007, 44: 904—910.
4. Kozulina IS, Isaeva EI, Samsygina GA. Human Metapneumovirus and Human Bocavirus in hospitalized Russian children with acute respiratory infection. 4thEuropaediatrics. Moscow, 2009: Abstract: 279.
5. Tyumentsev А.1., Tikunova N.V., Tikunov A.Y, Babkin I.V. Recombination in the evolution of human bocavirus. Infect. Genet. Evol., 2014, 28:11—14. (in Russ.)
6. Kondratiyeva T.YU., Shvets E.YU., Yevseyeva E.L., Gorelov A.V Epidemiological aspects bocavirus infection in children. Infektsionnyye Вolezni. 2008. 6(2):10—16. (in Russ.)
7. Malova I.A., Baranova I.P. The role of metapneumovirus and bokavirus in the development of acute respiratory infections in hospitalized patients during the 2011—2014 epidseasons in the Penza region. Detskie Infekcii=Children's Infections, 2016. 15(1):59—63. (in Russ.) https://doi.org/10.22627/2072-8107-2016-15-1-59-63
8. Musa Y., Keller N., Mandelboim M. et al. High rate of Human Bocavirus and Adenovirus coinfection in hospitalized Israeli children. J. Clin. Microbiol., 2008 Jan, 46 (1): 334—337.
9. BoivinG., SerresG., CoteS. etal. Human metapneumovirus infections in hospitalizedchildren. Emerg. Infect. Dis., 2003, 9(6): 634—640.
10. Yevseyeva E.L., Gorelov A.V., Kondratiyeva T.YU., Yatsyshina S.B., Shipulin G.A. Clinical and epidemiological features of metapneumovirus infection in children. Infektsionniye Вolezni, 2008, 6(3):27—32. (in Russ.)
11. Kozulina I.S., Samsygina G.A., Isayeva E.I., Legkova T.P., Shevchenko N.N., Donin I.M., Pavlov S.A. Bocavirus — new infectious agent in the etiology of acute respiratory diseases in children. Pediatriya, 2009, 88(6):51—54. (in Russ.)
Review
For citations:
Kaluzhskich T.I., Savinykh N.A., Savinykh M.V., Utenkova E.O. Features of metapneumovirus and bocavirus infections in children. CHILDREN INFECTIONS. 2020;19(3):12-14. (In Russ.) https://doi.org/10.22627/2072-8107-2020-19-3-12-14
Views:
10237
Email this article 