A case of reactivation of chronic Epstein-Barr viral infection, complicated by hepatitis, in a teenager with COVID-19
https://doi.org/10.22627/2072-8107-2022-21-2-57-59
Abstract
The article presents a clinical case of reactivation of chronic Epstein-Barr viral (EBV) infection complicated by the development of hepatitis in a 15-year-old teenager with COVID-19, which is of interest to infectious disease practitioners, pediatricians and other specialists in terms of the clinical course and differential diagnosis of these two viral diseases.
It is shown that the reactivation of EBV against the background of the current new coronavirus infection COVID-19, accompanied by an increase in the level of aminotransferases in the blood, leads to a more severe course and prolonged stay of the patient in the hospital, as well as the appointment of additional drug therapy with subsequent rehabilitation measures.
About the Authors
A. V. Bitsueva
Krasnogorsk City Hospital № 2 of the Ministry of Healthcare of the Moscow region; Research clinical institute of childhood of the Ministry of Healthcare of the Moscow region
Russian Federation
Russian Federation
Krasnogorsk
Mytischi
S. G. Gorbunov
Research clinical institute of childhood of the Ministry of Healthcare of the Moscow region; Russian Medical Academy of Continuig Professional Education of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
MD
Mytischi
Moscow
I. A. Nikulina
Research clinical institute of childhood of the Ministry of Healthcare of the Moscow region
Russian Federation
Russian Federation
Mytischi
References
1. World Health Organization (WHO) Coronavirus disease (COVID-19) pandemic. (Электронный ресурс). URL: https://www.who.int/emergencies/diseases/novel-coronavirus-2019 (дата доступа 31.03.2020).
2. Cao Q., Chen Y.C., Chen C.L., Chiu C.H. SARS-CoV-2 infection in children: transmission dynamics and clinical characteristics. J. Formos. Med. Assoc. 2020; 119(3): 670—673. DOI: 10.1016/j.jfma.2020.02.009
3. Han X., Li X., Xiao Y., Yang R., Wang Y., Wei X. Distinct characteristics of COVID-19 infection in children. Front. Pediatr. 2021; 9:619738. DOI: 10.3389/fped.2021.619738
4. Lu X., Zhang L., Du H. et al. SARS-CoV-2 infection in children. N. Engl. J. Med. 2020; 382(17): 1663—1665. DOI:1056/NEJMc2005073
5. Solomay T.V., Semenenko T.A., Isaeva E.I., Vetrova E.N., Chernyshova A.I., Romenskaya E.V., Karazhas N.V. COVID-19 and the risk of herpesvirus reactivation. Epidemiologiya i Infektsionnye Bolezni. Aktual’nye Voprosy=Epidemiology and Infectious Diseases. Сurrent Items. 2021; 11(2):55—62. (In Russ)
6. Bu W., Hayes G.M., Liu H., et al. Kinetics of Epstein-Barr Virus (EBV) neutralizing and virus-specific antibodies after primary infection with EBV. Clin. Vaccine Immunol. 2016; 23(4):363—69. DOI: 10.1128/CVI.00674-15
7. Draborg A.H., Duus K., Houen G. Epstein-Barr virus in systemic autoimmune diseases. Clin. Dev. Immunol. 2013; 2013:535738. DOI: 10.1155/2013/535738
8. Polyakova A.S., Bakradze M.D., Dzhivanshiryan G.V., Tatochenko V.K. Modern understanding of Epstein-Barr viral infection. Farmateka=Pharmateca. 2019; 26(10): 27—34. (In Russ)
9. Sandler Yu.G., Vinnitskaya E.V., Khaymenova T.Yu., Bordin D.S. Clinical aspects of liver damage in COVID-19. Effektivnaya Farmakoterapiya= Effective Pharmacotherapy. 2020; 16(15):18—23. DOI: 10.33978/2307-3586-2020-16-15-18-23 (In Russ)
10. Zaytsev I.A., Kiriyenko V.T. Hepatitis caused by the Epstein-Barr virus. Meditsinskaya Gazeta «Zdorovye Ukrainy 21 Stoletiya»=Medical Newspaper «Health of Ukraine of the 21st Century». 2016; 382(9): 52. (In Russ)
Review
For citations:
Bitsueva A.V., Gorbunov S.G., Nikulina I.A. A case of reactivation of chronic Epstein-Barr viral infection, complicated by hepatitis, in a teenager with COVID-19. CHILDREN INFECTIONS. 2022;21(2):57-59. (In Russ.) https://doi.org/10.22627/2072-8107-2022-21-2-57-59
Views:
494
Email this article 