Features of the course of COVID-19 in children undergoing outpatient treatment
https://doi.org/10.22627/2072-8107-2022-21-3-18-21
Abstract
Objective: to study the clinical and epidemiological features of the course of a new coronavirus infection in children of different ages undergoing outpatient treatment.
The study participants were 812 children with COVID-19 aged from 1 month to 17 years, who were on outpatient treatment in the children's polyclinic of the city of Kirov from July to December 2021. The average age of patients with COVID-19 was 5.9 ± 1.1 years. Among the sick young children there were 28%, adolescents — 16%. In 76% of cases, contact with patients with a new coronavirus infection was detected, mainly in the family, as well as in educational institutions. In 70% of cases, an early request for medical help was registered — in the first three days of illness. In most cases (89%), a mild severity of the disease was established with the development of subfebrile fever and pharyngitis. Rhinitis phenomena were recorded in 20% of cases. 7% of children complained of a dry cough. Lung tissue lesion (RG1) was detected in 5% of patients, gastrointestinal tract — 5%. In adolescents, the phenomena of rhinitis, pharyngitis, dry cough were less common than in other age groups. Recombinant interferon alpha-2b and umifenovir were used for etiotropic therapy. All children recovered within 7—10 days from the onset of the disease.
References
1. Ludvigsson J.F. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr. 2020; 109(6):1088—1095. https://doi.org/10.1111/apa.15270.
2. Cavallo F, Rossi N, Chiarelli F. Novel coronavirus infection and children. Acta Biomed. 2020, 11; 91(2):172—176. https://doi.org/10.23750/abm.v91i2.9586.
3. Нamming I Timens W Bulthuis ML Lely AT Navis G van Goor H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus: a first step in understanding SARS pathogenesis. J Pathol. 2004; 203:631—637. https://doi.org/10.1002/path.1570.
4. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; 395(10223):497—506. https://doi.org/10.1016/S0140-6736(20)30183-5.
5. Melekhina E.V., Gorelov A.V., Muzyka A.D. Clinical characteristics of COVID-19 in children of different ages. Literature review as of April 2020. Voprosy Рrakticheskoy Реdiatrii=Clinical Practice in Pediatrics. 2020: 15(2):7—20. (In Russ.) https://doi.org/10.20953/1817-7646-2020-2-7-20
6. Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 Infection in Children. N Engl J Med. 2020 Mar 18. https://doi.org/10.1056/NEJMc2005073.
7. Qiu H, Wu J, Hong L, Luo Y, Song Q, Chen D. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study. Lancet Infect Dis. 2020 Jun; 20(6):689—696. https://doi.org/ 10.1016/S1473-3099(20)30198-5.
8. Mazankova L.N, E.R. Samitova, I.M. Osmanov, I I. Afukov, N.A. Dracheva, A.B. Malakhov, T.A. Gutyrchik, V.G. Akimkin, A.A. Ploskireva, L.O. Taranov. Clinical and epidemiological features of the course of the new coronavirus infection COVID-19 in children during periods of an increase in the inci dence in Moscow in 2020—2021. Detskie Infektsii=Children's Infections. 2021: 20(3): 5—10. (In Russ.) https://doi.org/ 10.22627/2072-8107-2021-20-3-5-10
9. Shakmaeva M.A., T.M. Chernova, V.N. Timchenko, T.A. Nachinkina, K.V. Tetyushin, T.A. Kaplina, M.D. Subbotina, O.V. Bulina, O.I. Afanasyeva. Features of a new Сoronavirus infection in children of different ages. Detskie Infektsii=Children's Infections. 2021; 20(2):5—9. (In Russ.) https://doi.org/10.22627/2072-8107-2021-20-2-5-9
10. Bezrodnova S.M., N.A. Yatsenko, G.M. Sirazhov. Clinical, laboratory characteristics of a new Сoronavirus Infection in children in the Stavropol Territory. Detskie Infektsii=Children's Infections. 2021: 20(4):18—21. (In Russ.) https://doi.org/10.22627/2072-8107-2021-20-4-18-21
11. Bolatova D.G., Kairgeldinova M.K., Kazhybay M.E., Myrzakulova A.S., Turlybekova S.A., Sin M.A., Zhupenova D.E., Omirzakova P.A. Clinical characteristics of a new coronavirus infection (COVID-19) in children hospitalized in a hospital in Karaganda. Detskie Infektsii= Children's Infections. 2022: 21(1):45—48. (In Russ.) https://doi.org/10.22627/2072-8107-2022-21-1-45-48
12. Interim guidelines «Prevention, diagnosis and treatment of new coronavirus infection (COVID-19)». Version 11 (05/07/2021): 224. (in Russ.)
Review
For citations:
Bondarenko A.L. Features of the course of COVID-19 in children undergoing outpatient treatment. CHILDREN INFECTIONS. 2022;21(3):18-21. (In Russ.) https://doi.org/10.22627/2072-8107-2022-21-3-18-21
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