INFECTION AND IMMUNITY: CURRENT ISSUES IN PEDIATRIC PRACTICE
https://doi.org/10.22627/2072-8107-2015-14-1-36-43
Abstract
The article contains current data on the age-dependent physiological features of children’s immunity. Special attention is given to the specific stages of humoral and cell mediated immunity formation, critical periods of increased risk of infections and other pathology are noted. Also, the article defines the factors affecting immune system development, such as breastfeeding, balanced nutrition, different types of cold training and harmfulness of irrational antibiotic therapy. Particular reference is made to the role of interferons in increasing functional activity of the immune system and the improvement of immune disturbances.
About the Author
O. V. ZaytsevaRussian Federation
M.D., Dr. Sci. (Medicine), professor, honored doctor of Russian Federation, head of the Department of Pediatrics of the Moscow State University of Medicine and Dentistry; 20/1 Delegatskaya str., Moscow, Russia, 117036; +7(916)6505963
References
1. Grishina T.I. Immunologicheskie narusheniya, sposobstvuyuschie vozniknoveniyu opportunisticheskih infektsiy. [Immunological disorders, promoting the rise of opportunistic infections] / T.I. Grishina, L.G. Kuzmenko // Metodicheskie rekomendatsii — 2010. — s.23 (In Russ).
2. Bellanti J.A. Immunology IV: Clinical Application in Health and Disease. — Washington, 2012. — p.1063.
3. Janeway Ch.A. et al. Immunobiology (6th ed.). — Garland Science Publishing, New York — London, 2005 — p. 823.
4. Ershov F.I. Sistema interferona v norme i pri patologii. [Interferon system in health and disease] —M.: Meditsina, 1996. — c.239 (In Russ).
5. Malinovskaya V.V. Ontogenez sistemyi interferona i printsipyi primeneniya interferona v prakticheskoy pediatricheskoy praktike. [Ontogenesis of interferon system and interferon application principles in pediatric practice] // Sb. «Sovremennyie aspektyi primeneniya interferonov I drugih immunnomodulyatorov. [Modern aspects of using interferons and other immunomodulators] —1990. — s. 70—71 (In Russ).
6. Ahvatkina N.B. Osobennosti immuniteta detskogo vozrasta. / N.B. Ahvatkina, A.A. Mahalova // [Features of children’s immunity] Metodicheskie rekomendatsii. UDK 616-053.2-097(075.8) Kazan — 2012 (In Russ).
7. Samsyigina G.A. Chasto boleyuschie deti: problemyi diagnostiki, patogeneza i terapii. [Children with frequent acute respiratory infections: problems of pathogenesis, diagnosis and therapy] / G.A. Samsyigina, G.S. Koval // Lechaschiy vrach. — 2009. — №1(In Russ).
8. Yartsev M.N. Kliniko-laboratornaya otsenka immuniteta u detey i podhodyi k immunomoduliruyuschey terapii. / M.N. Yartsev, K.P. Yakovleva, M.V. Plahtienko. [Clinical and laboratory evaluation of immunity in children and approaches to immune modulation therapy] // Consilium medicum, prilozhenie pediatriya. — 2006. — №1 — s. 9—15 (In Russ).
9. Zaytseva O.V. Osobennosti vrozhdennogo immuniteta u detey s retsidiviruyuschim bronhoobstruktivnyim sindromom. [Peculiarities of innate immunity in children with reccurent wheezing] / O.V.Zaytseva, E.E. Lokshina, O.V. Gromadina, E.V. Dmitrieva i dr. // Rossiyskiy allergologicheskiy zhurnal, — 2013 —№1 — s.78—85 (In Russ).
10. Zaytseva O.V., Bronhialnaya astma u detey: sovremennyie aspektyi terapii. [Pediatric bronchial asthma: modern treatment aspects] / O.V. Zaytseva, O.A. Murtazaeva // Voprosyi sovremennoy pediatrii — 2011. — T.10 ,№6 — c.148—156 (In Russ).
11. Kenyon N. Enhanced cytokine generation by peripheral blood mononuclear cells in allergic and asthma subjects. / N. Kenyon, E. Kelly, N. Jarjour // Allergy Asthma Immunology — 2000. — V.85(2) — p.115—20.
12. Chuvirov G.N. Nespetsificheskaya profilaktika respiratornyih infektsiy [Nonspecific prevention of respiratory infections] // Meditsinskiy vestnik — 2008 — s.8 (In Russ).
13. Namazova L.S. Sovremennyie vozmozhnosti immunoterapii chasto boleyuschih detey s allergiey. [The potential of immunotherapy for sickly children with allergies ] / L.S. Namazova, V.V.Botvineva, N.I. Voznesenskaya // Pediatricheskaya farmakologiya — 2007. — T. 4. №1 — c. 27—32 (In Russ).
Review
For citations:
Zaytseva O.V. INFECTION AND IMMUNITY: CURRENT ISSUES IN PEDIATRIC PRACTICE. CHILDREN INFECTIONS. 2015;14(1):36-43. (In Russ.) https://doi.org/10.22627/2072-8107-2015-14-1-36-43