A clinical case of severe salmonella infection complicated by acute kidney injury in an 8-year-old child
O. B. Kovalev,
O. V. Molochkova,
V. V. Lutsenko,
A. A. Sakharova,
A. A. Kozlova,
A. A. Korsunsky,
E. V. Galeeva https://doi.org/10.22627/2072-8107-2023-22-2-61-64
Abstract
A clinical observation of a Salmonella infection (seeding Salmonella enteritidis) in an 8-year-old child with invasive diarrhea in the form of gastroenterocolitis with se- vere toxicosis and exsicosis of II degree is described. In dynamics, this infection was complicated by acute kidney injury. Inflammatory changes (increased C-reactive protein, procalcitonin, neutrophilia), coagulopathy (increased D-dimer, fibrinogen), metabolic acidosis, azotemia (increased urea, creatinine), filtration disorders, urinary syndrome (proteinuria up to 0.495 g/l in a single serving, cylindruria, bacteriuria, erythrocyturia up to 5850/ml). Ultrasound revealed pronounced phenomena of mesadenitis, inflammatory changes in the intestine, cholestasis, an increase in the size and echogenicity of the parenchyma of both kidneys. Acute kidney injury of the 2nd degree according to KDIGO (increase in serum creatinine by more than 3 times) of prerenal origin was diagnosed. As a result of the complex treatment, a positive trend was obtained and the child was discharged under outpatient supervision.
About the Authors
O. B. Kovalev
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
O. V. Molochkova
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
V. V. Lutsenko
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
A. A. Sakharova
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
A. A. Kozlova
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
A. A. Korsunsky
Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
Moscow
E. V. Galeeva
Children's City Clinical Hospital No. 9 named after G.N. Speransky
Russian Federation
Russian Federation
Moscow
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For citations:
Kovalev O.B., Molochkova O.V., Lutsenko V.V., Sakharova A.A., Kozlova A.A., Korsunsky A.A., Galeeva E.V. A clinical case of severe salmonella infection complicated by acute kidney injury in an 8-year-old child. CHILDREN INFECTIONS. 2023;22(2):61-64. (In Russ.) https://doi.org/10.22627/2072-8107-2023-22-2-61-64
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