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A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis

https://doi.org/10.22627/2072-8107-2024-23-1-62-67

Abstract

Purpose: to demonstrate a case of hemolytic-uremic syndrome (HUS) in a 5-year-old child associated with an acute intestinal infection of unknown etiology, occurring with hemocolitis. Results. During clinical and laboratory observation, edematous syndrome, oligoanuria, severe microangiopathic hemolytic anemia (decrease in hemoglobin, haptoglobin, increase in Lactate dehydrogenase), thrombocytopenia, consumption coagulopathy, hyperazotemia, acute kidney injury (AKI) according to KDIGO grade 2 (increase in serum creatinine more than 2 times) developed. As part of complex therapy with balanced crystalloid solutions with stimulation of diuresis, it was possible to achieve rapid restoration of diuresis on the 2nd day of hospital stay without the use of renal replacement therapy; he also received antibiotics, anticoagulants, transfusion of fresh frozen plasma and red blood cell suspension. Hyperazotemia was relieved within 5 days, as was thrombocytopenia. The follow-up recovery of renal function showed.

About the Authors

O. V. Molochkova
Pirogov Russian National Research Medical University
Russian Federation

Molochkova О. V. - PhD, Аssociate professor

Moscow



S. B. Orekhova
Children's City Clinical Hospital No. 9 named after. G.N. Speransky
Russian Federation

Orekhova S. B.

Moscow



R. V. Ovechkin
Pirogov Russian National Research Medical University
Russian Federation

Ovechkin R. V.

 Moscow



V. S. Vyshlova
Pirogov Russian National Research Medical University
Russian Federation

Vyshlova V. S.

Moscow



V. V. Glukhova
Pirogov Russian National Research Medical University
Russian Federation

Glukhova V. V.

Moscow



O. B. Kovalev
Pirogov Russian National Research Medical University
Russian Federation

Kovalev О. B. - MD, Professor

Moscow



N. Yu. Egorova
Pirogov Russian National Research Medical University
Russian Federation

Egorova N. Yu.

Moscow



A. B. Chashchukhina
Children's City Clinical Hospital No. 9 named after. G.N. Speransky
Russian Federation

Chashchukhina A. B.

Moscow



V. A. Masyakin
Children's City Clinical Hospital No. 9 named after. G.N. Speransky
Russian Federation

Masyakin V. A.

Moscow



E. P. Egorova
Children's City Clinical Hospital No. 9 named after. G.N. Speransky
Russian Federation

Egorova E. P.

Moscow



A. A. Sakharova
Children's City Clinical Hospital No. 9 named after. G.N. SperanskyMasyakin V. A.
Russian Federation

Sakharova A. A.

Moscow



A. G. Okhtyarkina
Pirogov Russian National Research Medical University
Russian Federation

Okhtyarkina A. G.

Moscow



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For citations:


Molochkova O.V., Orekhova S.B., Ovechkin R.V., Vyshlova V.S., Glukhova V.V., Kovalev O.B., Egorova N.Yu., Chashchukhina A.B., Masyakin V.A., Egorova E.P., Sakharova A.A., Okhtyarkina A.G. A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis. CHILDREN INFECTIONS. 2024;23(1):62-67. (In Russ.) https://doi.org/10.22627/2072-8107-2024-23-1-62-67

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ISSN 2072-8107 (Print)
ISSN 2618-8139 (Online)