Whooping cough in newborns
https://doi.org/10.22627/2072-8107-2025-24-1-33-36
Abstract
The relevance of the problem of whooping cough in newborns is due to the severity of clinical manifestations and high mortality.
The aim of the work is to present the data available in the literature on the causes of the unfavorable course of whooping cough in newborns, illustrated by our own clinical examples, as well as to summarize the ways to solve this problem.
Materials and methods: a review of domestic and foreign literature over the past 10 years, including Internet resources, was conducted and our own clinical observations of newborns with whooping cough are presented.
Conclusion. Whooping cough in newborns and children of the first months of life develops due to the absence of maternal anti-whooping cough antibodies. The disease is often severe, ending in death. Prevention of whooping cough in newborns and infants should include mandatory vaccination of pregnant women in the 2nd or 3rd trimester of pregnancy.
About the Authors
A. L. RossinaRussian Federation
Moscow
S. B. Chuelov
Russian Federation
Moscow
N. V. Kondratenko
Russian Federation
Moscow
A. A. Guzhavina
Russian Federation
Moscow
Yu. V. Zhirkova
Russian Federation
Moscow
M. M. Nasser
Russian Federation
Moscow
A. A. Fomushkina
Russian Federation
Moscow
O. P. Popova
Russian Federation
Moscow
O. V. Shamsheva
Russian Federation
Moscow
References
1. Infectious diseases in children. Ed. by Uchaikin V.F., Shamsheva O.V. M .: «GEOTAR-Media», 2022:920. (In Russ.)
2. Alekseeva I.A., Perelygina O.V., Nikityuk N.F., ObukhovYu.I., Gavrilova N.A., Kolyshkina E.D., Tutukova V.I. Epidemiological process of pertussis in the Russian Federation. Medical Аlmanac. 2019; 3—4(60):24—32. (In Russ.) doi.org/10.21145/2499-9954-2019-3-24-32
3. Krieger E.A., Samodova O.V., Titova L.V. Pertussis immunity in pregnant women and factors associated with seronegative status. Russian Journal of Infection and Immunity. 2021; 11(1):131—136. (In Russ.) doi: 10.15789/2220-7619-ITP-1406
4. Fung T.-H., Cherk S. W.-W. A review of five young infants with pertussis. Journal of Paediatric Respirology and Critical Care. 2006; 2(1):10—13.
5. Decker M.D., Edwards K.M. Pertussis (Whooping Cough). J. Infect Dis. 2021; 224:S310—S320. doi: 10.1093/infdis/jiaa469.
6. Healthcare in Russia. 2023: Statistical Collection. Rosstat. M., 2023.:179. (In Russ.)
7. Kostinov А.M., Kostinov M.P. Pertussis Incidence And The Effect Of Revaccination Of Preschool And School Children. Russian Journal of Infection and Immunity. 2018; 8(3):284—294. (In Russ.) doi: 10.15789/2220-7619-2018-3-284-294
8. Kandeil W., van den Ende C., Bunge E.M., Jenkins V.A., Ceregido M.A., Guignard A. A systematic review of the burden of pertussis disease in infants and the effectiveness of maternal immunization against pertussis. Expert Rev. Vaccines. 2020; 19(7):621—638. doi: 10.1080/14760584.2020.1791092.
9. Petrova M.S., Popova O.P., Borisova O.Y., Abramova E.N., Vartanyan R.V., Kelli E.I. Pertussis In Children Of Early Age. Epidemiology and Infectious Diseases. 2012; 17(6):19—24. (In Russ.) doi: 10.17816/EID40704
10. Update on Immunization and Pregnancy: Tetanus, Diphtheria, and Pertussis Vaccination. Obstet Gynecol. 2017; 130(3):e153—e157. doi: 10.1097/AOG.0000000000002301.
11. Kharit S.M., KonstantinovaYu.E. International practice in vaccination of pregnant women against pertussis (a review). Journal Infectology. 2021; 13(1):29—37. (In Russ.) doi.org/10.22625/2072-6732-2021-13-1-29-37
12. Normal pregnancy. Clinical guidelines of the Ministry of Health of the Russian Federation, 2023. (In Russ.)
Review
For citations:
Rossina A.L., Chuelov S.B., Kondratenko N.V., Guzhavina A.A., Zhirkova Yu.V., Nasser M.M., Fomushkina A.A., Popova O.P., Shamsheva O.V. Whooping cough in newborns. CHILDREN INFECTIONS. 2025;24(1):33-36. (In Russ.) https://doi.org/10.22627/2072-8107-2025-24-1-33-36