Профилактика врожденного токсоплазмоза
https://doi.org/10.22627/2072-8107-2025-24-2-43-50
Аннотация
Актуальность проблемы врожденного токсоплазмоза обусловлена широкой распространенностью токсоплазмоза в мире, тяжестью течения врожденного токсоплазмоза и возможным развитием резидуальных изменений со стороны центральной нервной системы, органов чувств и других внутренних органов.
Целью работы является обобщение имеющихся в литературе данных об этиологии, эпидемиологии, клинике, диагностике, лечении и профилактике врожденного токсоплазмоза.
Материалы и методы. Проведен обзор отечественной и зарубежной литературы за последние 25 лет, в том числе, интернет-ресурсов, включая поисковые системы PubMed, Cochrane Library, Google Scholar.
Заключение. Для предупреждения врожденного токсоплазмоза возможно осуществление скрининга как планирующих беременность, так и беременных женщин. В случае подтвержденного инфицирования беременных женщин лечащим врачом может быть рассмотрено проведение медикаментозной профилактики, которая в РФ может осуществляться с использованием макролидного препарата спирамицина. Одним из направлений профилактики является разработка вакцин, среди которых особенно перспективными представляются вакцины на основе наночастиц.
Ключевые слова
Toxoplasma gondii,
врожденный токсоплазмоз,
беременные женщины,
новорожденные дети,
профилактика,
вакцины
Об авторах
А. Г. Булгакова
ФГАОУ ВО Российский национальный исследовательский медицинский университет им. Н.И. Пирогова МЗ РФ
Россия
Россия
Булгакова Анна Георгиевна, студент 6 курса
Москва
С. Б. Чуелов
ФГАОУ ВО Российский национальный исследовательский медицинский университет им. Н.И. Пирогова МЗ РФ
Россия
Россия
Чуелов Сергей Борисович, д.м.н., профессор кафедры инфекционных болезней у детей
Москва
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Рецензия
Для цитирования:
Булгакова А.Г., Чуелов С.Б. Профилактика врожденного токсоплазмоза. ДЕТСКИЕ ИНФЕКЦИИ. 2025;24(2):43-50. https://doi.org/10.22627/2072-8107-2025-24-2-43-50
For citation:
Bulgakova A.G., Chuelov S.B. Prevention of congenital toxoplasmosis. CHILDREN INFECTIONS. 2025;24(2):43-50. (In Russ.) https://doi.org/10.22627/2072-8107-2025-24-2-43-50
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