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New coronavirus infection (COVID-19) in an initially healthy teenager — focus on acute myocardial injury

https://doi.org/10.22627/2072-8107-2025-24-2-55-59

Abstract

Objective: to demonstrate a clinical case of fulminant COVID-19 in a teenager without comorbid pathology. The article presents a clinical case of a fulminant course of a new coronavirus infection in a 16-year-old teenager with the development of multiple organ failure (bilateral polysegmental pneumonia, grade 2 respiratory failure, cardiovascular and renal-hepatic insufficiency). The emphasis is placed on heart damage with the development of acute myocardial damage, which is confirmed by high levels of troponin I and pericarditis.

Conclusion: the described clinical case demonstrates the development of multiple organ failure and death in an initially healthy child. The development of acute myocardial injury is shown.

About the Authors

V. V. Sokolovskaya
Smolensk State Medical University
Russian Federation

Smolensk



A. A. Litvinova
Smolensk State Medical University
Russian Federation

Smolensk



A. V. Krikova
Smolensk State Medical University
Russian Federation

Smolensk



R. S. Kozlov
Smolensk State Medical University
Russian Federation

Smolensk



A. V. Shnyreva
Smolensk State Medical University
Russian Federation

Smolensk



E. A. Zhilina
Smolensk State Medical University
Russian Federation

Smolensk



References

1. Hoffmann M, Kleine-Weber H, Schroeder S, Krüger N, Herrler T, Erichsen S, Schiergens TS, Herrler G, Wu NH, Nitsche A, Müller MA, Drosten C, Pöhlmann S. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor. Cell. 2020 Apr 16;181(2):271—280.e8. https://doi.org/10.1016/j.cell.2020.02.052

2. Rafiee MJ, Friedrich MG. MRI of cardiac involvement in COVID-19. Br J Radiol. 2024 Aug 1; 97(1160):1367—1377. https://doi.org/10.1093/bjr/tqae086

3. Shi S, Qin M, Shen B, Cai Y, Liu T, Yang F, Gong W, Liu X, Liang J, Zhao Q, Huang H, Yang B, Huang C. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiol. 2020 Jul 1; 5(7):802—810. https://doi.org/10.1001/jamacardio.2020.0950

4. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020 Mar 17; 323(11):1061—1069. https://doi.org/10.1001/jama.2020.1585

5. Sokolovskaja V.V., Litvinova A.A. The effect of COVID-19 on the cardiovascular system: a literature review. Pediatrija Vostochnaja Evropa. 2024;12(1):64—77. (In Russ.) https://doi.org/10.34883/PI.2024.12.1.006

6. Giugni FR, Duarte-Neto AN, da Silva LFF, Monteiro RAA, Mauad T, Saldiva PHN, Dolhnikoff M. Younger age is associated with cardiovascular pathological phenotype of severe COVID-19 at autopsy. Front Med (Lausanne). 2024 Jan 8; 10:1327415. https://doi.org/10.3389/fmed.2023.1327415

7. Nikolopoulou GB, Maltezou HC. COVID-19 in Children: Where do we Stand? Arch Med Res. 2022 Jan; 53(1):1—8. doi: 10.1016/j.arcmed.2021.07.002.

8. Guo T, Fan Y, Chen M, Wu X, Zhang L, He T, Wang H, Wan J, Wang X, Lu Z. Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. 2020 Jul 1; 5(7):811— 818. doi: 10.1001/jamacardio.2020.1017.

9. Navolokina, Alla & Smereka, Jacek & Böttiger, Bernd & Pruc, Michał & Juárez-Vela, Raúl & Rahnama-Hezavah, Mansur & Rafique, Zubaid & Peacock, William & Safiejko, Kamil & Szarpak, Łukasz. (2023). The Impact of COVID-19 on Pediatric Cardiac Arrest Outcomes: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health. 2023:1104. doi: 10.3390/ijerph20021104.

10. Sanna, G., Serrau, G., Bassareo, P.P. et al. Children’s heart and COVID-19: Up-to-date evidence in the form of a systematic review. Eur J Pediatr. 2020; 179:1079—1087. https://doi.org/10.1007/s00431-020-03699-0


Review

For citations:


Sokolovskaya V.V., Litvinova A.A., Krikova A.V., Kozlov R.S., Shnyreva A.V., Zhilina E.A. New coronavirus infection (COVID-19) in an initially healthy teenager — focus on acute myocardial injury. CHILDREN INFECTIONS. 2025;24(2):55-59. (In Russ.) https://doi.org/10.22627/2072-8107-2025-24-2-55-59

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ISSN 2072-8107 (Print)
ISSN 2618-8139 (Online)