FIVE-YEAR EXPERIENCE OF HIGHLY ACTIVITY ANTIRETROVIRAL THERAPY IN CHILDREN WITH HIV-INFECTION
https://doi.org/10.22627/2072-8107-2015-14-2-35-40
Abstract
Clinical, immunological and virologic examination of 67 HIV infected children receiving highly activity antiretroviral therapy (HAART) within 12—60 months is conducted. HAART promoted suppression of HIV replication, increase of T-helpers count, reduction of clinical symptoms frequency and its expressiveness. At long HAART application the considerable part of patients needs therapy correction because of loss of efficiency of the starting scheme or development of side effects. For increase of therapy efficiency it is necessary lopinavir/ritonavir to include in HAART schemes, and also to carry out selection of preparations taking into account HIV drug resistance.
About the Authors
V. B. Denisenko
Rostov on Don State Medical University
Russian Federation
Associate Professor of the Department of Pediatric Infectious Diseases, Rostov on Don State Medical University, 344022, Rostov-on-Don, Nakhichevansky, 29; 8(863) 232-73-58
Russian Federation
Associate Professor of the Department of Pediatric Infectious Diseases, Rostov on Don State Medical University, 344022, Rostov-on-Don, Nakhichevansky, 29; 8(863) 232-73-58
E. N. Simovanyan
Rostov on Don State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Denisenko V.B., Simovanyan E.N. FIVE-YEAR EXPERIENCE OF HIGHLY ACTIVITY ANTIRETROVIRAL THERAPY IN CHILDREN WITH HIV-INFECTION. CHILDREN INFECTIONS. 2015;14(2):35-40. (In Russ.) https://doi.org/10.22627/2072-8107-2015-14-2-35-40
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