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Imported Opisthorchiasis in Moscow and a substantiation of an alternative concept for the hematogenous migration of Opisthorchis larvaе

https://doi.org/10.22627/2072-8107-2026-25-1-44-47

Abstract

The relevance of opisthorchiasis is due to its widespread prevalence in the wild in Russia and its ability to infect humans through the consumption of improperly cooked fish. The aim of this paper is to present available literature data on the epidemiology, clinical and laboratory manifestations, and diagnosis of opisthorchiasis, illustrated by a clinical example. This paper also presents an alternative theory for the hematogenous path of parasite migration in the definitive host. Materials and Methods: A review of recent Russian and international literature, including online resources, was conducted on the situation with opisthorchiasis in Russia and Moscow, as well as the pathogenesis of opisthorchiasis. A clinical observation of a patient with imported opisthorchiasis in Moscow was presented. Conclusion. The diagnosis of opisthorchiasis is based on the epidemiological history, clinical presentation, eosinophilia, and detection of multiple inflammatory foci in the liver. This diagnosis is confirmed by coproovoscopic and serological methods. Focal changes in the liver parenchyma can be explained by the hematogenous migration of opisthorchis larvae.

About the Authors

A. L. Rossina
Pirogov Russian National Research Medical University
Russian Federation

Moscow 



S. B. Chuelov
Pirogov Russian National Research Medical University
Russian Federation

Moscow 



N. V. Kondratenko
Speransky Children's City Clinical Hospital No. 9
Russian Federation

Moscow 



A. S. Ilyinskaya
Speransky Children's City Clinical Hospital No. 9
Russian Federation

Moscow 



A. Kh. Omarov
Speransky Children's City Clinical Hospital No. 9
Russian Federation

Moscow 



G. V. Smirnova
Speransky Children's City Clinical Hospital No. 9
Russian Federation

Moscow 



E. V. Grushitskaya
Speransky Children's City Clinical Hospital No. 9
Russian Federation

Moscow 



O. I. Zhdanova
Speransky Children's City Clinical Hospital No. 9
Russian Federation

Moscow 



References

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2. Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing. Gosudarstvennyy doklad «O sostoyanii sanitarno-epidemiologicheskogo blagopoluchiya naseleniya Rossiyskoy Federatsii v 2024 godu» [State report «On the state of sanitary and epidemiological welfare of the population of the Russian Federation in 2024»] [Internet]. Moscow; 2025 Available from: https://www.rospotrebnadzor.ru/documents/details.php?ELEMENT_ID=30171 (In Russ.)

3. Bronshtein AM, Burova SV, Malyshev NA, Davydova IV. Autokhtonnye sluchai ostrogo opistorkhoza v Moskovskoy oblasti [Autochthonous cases of acute opisthorchiasis in the Moscow region]. Epidemiologiya i Infektsionnye Bolezni. 2020;25(5):228—232. (In Russ.) doi:10.17816/EID64211

4. Kovalenko FP, Chernikova EA, Mikhelev VYu, Shatveryan GA. Eksperimental'noe obosnovanie novoy kontseptsii stanovleniya invazii Opisthorchis felineus u okonchatel'nogo khozyaina [Experimental substantiation of a new concept of Opisthorchis felineus invasion establishment in the definitive host]. Parazitologiya. 2005;39(3):257—262. (In Russ.) Available from: https://www.zin.ru/journals/parazitologiya/content/2005/ prz_2005_3_9_Kovalenko.pdf

5. Ter-Bagdasaryan LV, Sergeeva ON, Ratnikova LI. Trudnosti diagnostiki opistorkhoza v neendemichnom regione [Difficulties in diagnosing opisthorchiasis in a non-endemic region]. Infektsionnye Bolezni: Novosti, Mneniya, Obuchenie. 2025;14(1):112— 122. (In Russ.) doi:10.33029/2305-3496-2025-14-1-112-122


Review

For citations:


Rossina A.L., Chuelov S.B., Kondratenko N.V., Ilyinskaya A.S., Omarov A.Kh., Smirnova G.V., Grushitskaya E.V., Zhdanova O.I. Imported Opisthorchiasis in Moscow and a substantiation of an alternative concept for the hematogenous migration of Opisthorchis larvaе. CHILDREN INFECTIONS. 2026;25(1):44-47. (In Russ.) https://doi.org/10.22627/2072-8107-2026-25-1-44-47

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ISSN 2072-8107 (Print)
ISSN 2618-8139 (Online)