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Vulvovaginitis in сhildhood: differential diagnosis for pediatricians and pediatric gynecologists

https://doi.org/10.22627/2072-8107-2026-25-1-48-52

Abstract

Vulvovaginitis is the most common gynecological pathology in prepubertal girls, characterized by a high incidence rate (up to 93%) and a tendency to recur (up to 60%). The multifactorial nature of the disease and the non-specific clinical presentation create significant challenges for differential diagnosis. Objective: To systematize modern algorithms for the differential diagnosis of vulvovaginitis in girls to optimize the work of pediatricians and pediatric gynecologists at the outpatient stage. Materials and Methods: A review of current domestic and foreign literature sources, clinical guidelines, and protocols for the management of vulvovaginitis in childhood was conducted. Results: The article details the pathophysiological basis of vulvovaginitis, which are determined by the anatomical and physiological characteristics of girls. A classification of etiological factors is presented, distinguishing between non-specific (70—80% of cases) and specific causes. For the main disease entities, pathognomonic clinical features and recommended diagnostic methods are summarized in a comparative table. Conclusion: Effective diagnosis of vulvovaginitis in children requires a comprehensive multidisciplinary approach. Strict adherence to a structured diagnostic algorithm makes it possible to identify the cause of inflammation, prescribe adequate therapy, and avoid diagnostic errors.

About the Authors

E. V. Sibirskaya
Russian Children’s Clinical Hospital — a Branch of N.I. Pirogov Russian National Research Medical University; N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation; Russian University of Medicine of the Ministry of Healthcare of the Russian Federation
Russian Federation

 Moscow 



I. V. Karachentsova
Russian Children’s Clinical Hospital — a Branch of N.I. Pirogov Russian National Research Medical University; N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation

 Moscow  



P. O. Nikiforova
Russian Children’s Clinical Hospital — a Branch of N.I. Pirogov Russian National Research Medical University; N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation


D. D. Danilko
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation

 Moscow 



S. S. Bogatyryova
N.I. Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation

 Moscow 



References

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Review

For citations:


Sibirskaya E.V., Karachentsova I.V., Nikiforova P.O., Danilko D.D., Bogatyryova S.S. Vulvovaginitis in сhildhood: differential diagnosis for pediatricians and pediatric gynecologists. CHILDREN INFECTIONS. 2026;25(1):48-52. (In Russ.) https://doi.org/10.22627/2072-8107-2026-25-1-48-52

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ISSN 2072-8107 (Print)
ISSN 2618-8139 (Online)