CLINICAL CASE OF SKIN LESIONS WITH PARVOVIRUS B19 INFECTION

L. I. Ilienko; A. G. Pashinyan; V. Yu. Vasenova

doi:10.22627/2072-8107-2018-17-3-68-71

CLINICAL CASE OF SKIN LESIONS WITH PARVOVIRUS B19 INFECTION

L. I. Ilienko, A. G. Pashinyan, V. Yu. Vasenova

https://doi.org/10.22627/2072-8107-2018-17-3-68-71

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Abstract

Clinico-epidemiological characteristics of parvovirus В19 infection are presented. Especially dangerous is the virus for pregnant women in the first and second trimesters of pregnancy, as it can lead to spontaneous abortion, the development of non-immune dropsy or intrauterine fetal death. Infectious erythema is characterized by a bright erythema of the cheek skin — a symptom of «spanked» cheeks, a patchy-papular «lacy» rash on the skin of the trunk and extensor surfaces of the extremities, more common in children aged 4 to 10 years. Diagnosis of parvovirus infection B19 is based on the results of serological methods, PCR, detection of IgM, immunoblot IgM/IgG. A clinical case of infectious erythema in a girl of 5 years is described.

Keywords

infectious erythema, parvovirus B19

References

1. Cossart Y.E., Field A.M., Cant B., Widdows D. Parvovirus-like particles in human sera. Lancet .1975;11(1):72-3.

2. Candotti D., Etiz N., Parsyan A., Allain J.P. Identification and characterization of persistent human erythrovirus infection in blood donor samples. J Virol .2004; 78(22):12169-78.

3. Parsyan A,. Szmaragd C., Allain J.P., Candotti D. Identification and genetic diversity of two human parvovirus B19 genotype 3 subtypes. J Gen Virol .2007; 88( 2):428-31.

4. Filippone C., Zhi N., Wong S., Lu J., Kajigaya S., Gallinella G., Kakkola L., Söderlund-Venermo M., Young N.S., Brown KE.VP1u phospholipase activity is critical for infectivity of full-length parvovirus B19 genomic clones. Virology. 2010; 374(2):444-52. https://doi.org/10.1016/j.virol.2008.01.002

5. Anderson L.J., Tsou C., Parker R.A., Chorba T.L., Wulff H., Tattersall P., Mortimer P.P. Detection of antibodies and antigens of human parvovirus B19 by enzyme-linked immunosorbent assay. J Clin Microbiol. 1986; 24:522-6.

6. Marano G., Vaglio S., Pupella S., Facco G., Calizzani G., Candura F., Liumbruno G.M, Grazzini G. Human Parvovirus B19 and blood product safety: a tale of twenty years of improvements. Blood Transfus. 2015;13(2):184-196. https://doi.org/10.2450/2014.0174.14

7. Lamont R.F., Sobel J.D., Vaisbuch E., Kusanovic J.P., Mazaki-Tovi S., Kim S.K., Uldbjerg N., Romero R. Parvovirus B19 infection in human pregnancy. BJOG. 2011;118(2):175-86.

8. Subtil D., Garabedian C., Chauvet A. Parvovirus B19 infection and pregnancy. Presse Med. 2015; 44(6):647-53. https://doi.org/10.1016

9. Enders M., Klingel K., Weidner A., Baisch C., Kandolf R., Schalasta G., Enders G. Risk of fetal hydrops and non-hydropic late intrauterine fetal death after gestational parvovirus B19 infection. Journal of clinical virology: the official publication of the Pan American Society for Clinical Virology. 2010; 49(3):163-8. https://doi.org/10.1016/j.jcv.2010.07.014

10. Shabani Z., Esghaei M., Keyvani H., Shabani F., Sarmadi F., Mollaie H., Monavari S.H. Relation between parvovirus B19 infection and fetal mortality and spontaneous abortion. Med J Islam Repub Iran. 2015; 7(29):197.

11. Ugai S., Aizawa Y., Kanayama T., Saitoh A. Parvovirus B19: A Cause of Sepsislike Syndrome in an Infant. Pediatrics. 2018; 141(6). pii: e20171435. https://doi.org/10.1542/peds.2017-1435.

12. Sidorova I.S., Kulakova V.I., Makarov I.O. Guide to Midwifery Moscow: Meditcina, 2006: 362. (In Russ.)

13. Pashinyan A.G., Runikhina N.A., Mokeeva E.Yu. Erytema infectiosum: clinical case. Rossiyskiy Zhurnal Kozhnykh i Venericheskikh Bolezney = Russian Journal of Skin and Venereal Disease 2016;19(4):206-209. (In Russ.) https://doi.org/:10.18821/1560-9588-2016-19-4-206-209

14. Gustafsson I., Kaldensjö T., Lindblom A., Norbeck O., Henter J.I., Tolfvenstam T., Broliden K. Evaluation of parvovirus B19 infection in children with malignant or hematological disorders. Clin. Infect. Dis. 2010; 50(10):1426-7 https://doi.org/10.1086/652286.

15. Dingli D., Pfizenmaier D.H., Arromdee E., Wennberg P., Spittell P.C., Chang-Miller A., Clarke B.L. Severe digital arterial occlusive disease and acute parvovirus B19 infection. Lancet. 2000; 356:312-314. https://doi.org/10.1016/S0140-6736(00)02512-5.

16. Kerr J.R. Pathogenesis of human parvovirus B19 in rheumatic disease. Ann. Rheum. Dis. 2000; 59:672-683. https://doi.org/10.1136/ard.59.9.672.

17. Bock C.T., Düchting A., Utta F., Brunner E., Sy B.T., Klingel K., Lang F., Gawaz M., Felix S.B., Kandolf R. Molecular phenotypes of human parvovirus B19 in patients with myocarditis. World J Cardiol. 2014; 26;6(4):183-95. https://doi.org/10.4330/wjc.v6.i4.183.

18. Tesapirat L., Wanlapakorn N., Chieochansin T., Poovorawan Y. Parvovirus b19 infection presenting as acute hepatitis and transient anemia in a previously healthy child. Southeast Asian J Trop Med Public Health. 2015; 46(2):226-30.

19. Valencia Pacheco G., Nakazawa Ueji Y.E., Rodríguez Dzul E.A., Angulo Ramírez A.V., López Villanueva R.F., Quintal Ortiz I.G., Rosado Paredes EP. Serological and molecular analysis of parvovirus B19 infection in Mayan women with systemic lupus erythematosus in Mexico. Colomb Med (Cali). 2017; 48(3):105-112. https://doi.org/10.25100/cm.v48i3.2981.

20. Peterlana D., Puccetti A., Corrocher R., Lunardi C. Serologic and molecular detection of human parvovirus B19 infection. Clin Chim Acta. 2006; 372:14-23.

21. Koppelman M.H., van Swieten P., Cuijpers H.T. Real-time polymerase chain reaction detection of parvovirus B19 DNA in blood donations using a commercial and an in-house assay. Transfusion. 2011; 51(6):1346-54. https://doi.org/10.1111.

22. Juhl D., Gorg S., Hennig H. Persistence of parvovirus B19 (B19V) DNA and humoral immune response in B19V-infected blood donors. Vox Sang. 2014; 107:226-232.

23. Nadimpalli S.S., Miller R.S., Kamath V.M., Farkouh C.R., NhanChang C.L., Rathe J.A.,, Collins A., Duchon J.M., Neu N., Simpson L.L., Ratner A.J. Congenital Parvovirus B19 Infection: Persistent Viremia and Red Blood Cell Aplasia. Open Forum Infect Dis. 2015; 2(2):049. https://doi.org/10.1093/ofid/ofv049

24. Bonvicini F., Puccetti C., Salfi N.C., Guerra B., Gallinella G., Rizzo N., Zerbini M. Gestational and Fetal Outcomes in B19 Maternal Infection: a Problem of Diagnosis. J Clin Microbiol. 2011; 49(10):3514-3518. https://doi.org/10.1128/JCM.00854-11

For citations:

Ilienko L.I., Pashinyan A.G., Vasenova V.Yu. CLINICAL CASE OF SKIN LESIONS WITH PARVOVIRUS B19 INFECTION. CHILDREN INFECTIONS. 2018;17(3):68-71. (In Russ.) https://doi.org/10.22627/2072-8107-2018-17-3-68-71

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ISSN 2072-8107 (Print)
ISSN 2618-8139 (Online)

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CHILDREN INFECTIONS

CLINICAL CASE OF SKIN LESIONS WITH PARVOVIRUS B19 INFECTION

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CHILDREN INFECTIONS

CLINICAL CASE OF SKIN LESIONS WITH PARVOVIRUS B19 INFECTION

Full Text:

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About the Authors

References

Review

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