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The efficiency of interferon therapy for acute respiratory viral infections in young children

https://doi.org/10.22627/2072-8107-2020-19-1-13-16

Abstract

The problem of choosing an effective etiotropic treatment for acute respiratory viral infections in young children is one of the urgent in pediatrics.

Materials and methods. The article presents data on the mechanism of the combined antiviral and immunomodulating action of the drug recombinant interferon alpha-2b. The results of observation of 80 children aged 3 to 12 months with acute respiratory viral infections of various etiologies are presented.

Results. Clinical and laboratory indicators of intoxication that occur during acute respiratory viral infections in children have been identified. It has been shown that the use of rectal suppositories of interferon alpha-2b in the treatment of young children with acute respiratory viral infections causes a rapid relief of the clinical symptoms of the disease and helps to reduce the duration of hospital treatment of patients.

About the Authors

T. K. Chudakova
Saratov State Medical University of V.I. Razumovsky
Russian Federation

Tatyana Chudakova - PhD, Associate Professor of the department of infectious diseases in children andoutpatient pediatrics of N.R. Ivanov, Saratov state medical university of V.I. Razumovsky.

Saratov.



E. V. Mikhaylova
Saratov State Medical University of V.I. Razumovsky
Russian Federation

Elena Mikhaylova - MD, Professor, Head of the department of infectious diseases in children andoutpatient pediatrics of N.R.Ivanov, Saratov state medical university of V.I. Razumovsky.

Saratov.



References

1. Mikhailova E.V., Chudakova T.K., Danilov A.N. Clinical features of acute respiratory viral infections and improved therapy in the group of frequently ill children. Epidemiologiya i Infektsionnyye Bolezni. Aktual'nyye Voprosy=Epidemiology and Infectious Diseases. Actual Issues. 2014; 3:58—62. (In Russ.)

2. Mikhailova E.V., Chudakova T.K., Yarushkina M.S., Romanovskaya A.V., Hvorostukhina N.F. Respiratory syncytial viral infection: clinical and laboratory features. Detskie Infektsii=Children's Infections. 2017; 16(2):23—25. (In Russ.) https://doi.org/10.22627/2072-8107-2017-16-2-23-25

3. Chudakova T.K., Romanovskaya A.V., Mikhailova E.V., Hvorostukhina N.F., Tseka Yu.S. The choice of etiotropic therapy of acute respiratory viral infections in children. Voprosy Рrakticheskoy Рediatrii=Questions of Рractical Рediatrics. 2015; 10(5):77—83. (In Russ.) https://doi.org/10.20953/1817-7646-2015-5-77-82

4. Bulgakova V.A. Optimization of etiotropic therapy for acute respiratory viral infections and influenza in children as a way to reduce medical overload. Voprosy Рrakticheskoy Рediatrii = Questions of Рractical Рediatrics. 2014; 9(5):26—34. (In Russ.)

5. Ershov F.I., Romantsov M.G., Melnikova I.Yu. Antivirusnyye preparaty v praktike pediatra: spravochnik praktikuyushchego vracha. = Antiviral drugs in the practice of a pediatrician: a practitioner's guide. M.: GEOTAR-Media; 2013. (In Russ.)

6. Mail D., Brostoff J., Roth D B, Reutt A. Immunologiya = Immunology. M.: Logosphere; 2007. (In Russ.)

7. Vysochina I.L., Shostakovich-Koretskaya A.E. Clinical and immunological correlation analysis in children with repeated respiratory viral diseases. Bulletin of St. Petersburg State Medical Academy named after I.I.Mechnikov. 2006; 3: 9—43. (In Russ.)

8. Register of medicines of Russia «Encyclopedia of drugs». 21st ed. Reworker. and add. M.: RLS; 2013. (In Russ.)

9. Infectious Diseases: National Guide / Ed. N.D. Yushchuk, Yu.Ya. Vengerov. M.: GEOTAR-Media, 2015. (In Russ.)


Review

For citations:


Chudakova T.K., Mikhaylova E.V. The efficiency of interferon therapy for acute respiratory viral infections in young children. CHILDREN INFECTIONS. 2020;19(1):13-16. (In Russ.) https://doi.org/10.22627/2072-8107-2020-19-1-13-16

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ISSN 2072-8107 (Print)
ISSN 2618-8139 (Online)