Bronchial obstructive syndrome in primary infection with Mycobacterium tuberculosis in children
https://doi.org/10.22627/2072-8107-2020-19-4-34-37
Abstract
Рurpose. The aim is to study the influence of primary Mycobacterium tuberculosis infection on the occurrence of bronchial obstruction syndrome in children.
Materials and methods. A retrospective study of primary medical records of 60 children aged 2 to 6 years for the period from 2016 to 2018, with diagnoses of acute obstructive bronchitis and acute respiratory infection. The patients were divided into 2 groups: group I — 30 children with bronchial obstruction syndrome, II group — 30 people — children with common cold without bronchial obstruction syndrome (control group). We studied the dynamics of reactions to the Mantoux test with 2 TE, contacts with tuberculosis patients, the effectiveness of Vaccinum tuberculosis (BCG-M) vaccination, allergological history, the nature of feeding and allergizing factors in everyday life. Data processing was performed using the NanoStat 1.6 program. Тhe сritical level of statistical significance was assumed to be p < 0.05.
Results. It was found that primary Mycobacterium tuberculosis (MBT) infection in children under 4 years has a direct correlation with a high risk of bronchial obstruction syndrome. At the same time, bronchial obstruction syndrome occurred in the absence of local tuberculosis, which can be considered as a paraspecific reaction in the case of primary MBT infection.
Сonclusions. The observed relationship between the two phenomena determines the need to examine young children with bronchial obstruction syndrome for MBT infection.
About the Authors
A. L. Salova
Yaroslavl state medical University of the Ministry of health of the Russian Federation
Russian Federation
Russian Federation
Alexandra Salova, assistant of the Department of Phthisiology
Yaroslavl
O. G. Chelnokova
Yaroslavl state medical University of the Ministry of health of the Russian Federation
Russian Federation
Russian Federation
MD
Yaroslavl
L. I. Mozzhukhina
Yaroslavl state medical University of the Ministry of health of the Russian Federation
Russian Federation
Russian Federation
MD
Yaroslavl
T. A. Kogut
Yaroslavl state medical University of the Ministry of health of the Russian Federation
Russian Federation
Russian Federation
PhD
Yaroslavl
References
1. Зайцева С.В., Муртазаева О.А. Синдром бронхиальной обструкции у детей. Трудный пациент. 2012; 2—3(10): 34—37. [Zaitseva S.V., Murtazaeva O.A. Syndrome of bronchial obstruction in children. Trudnyy Рatsiyent=Difficult Рatient. 2012; 2—3(10): 34—37. (In Russ.)]
2. Котлуков В.К., Блохин Б.М., Румянцев А.Г., Делягин В.М., Мельникова М.А. Синдром бронхиальной обструкции у детей раннего возраста с респираторными инфекциями различной этиологии: особенности клинических проявлений и иммунного ответа. Педиатрия. 2006; 3:14—21. [Kotlukov V.K., Blokhin B.M., Rumyantsev A.G., Delyagin V.M., Melnikova M.A. Syndrome of bronchial obstruction in young children with respiratory infections of various etiologies: features of clinical manifestations and immune response. Рediatriya=Pediatrics. 2006; 3:14—21. (In Russ.)]
3. Национальная программа «Бронхиальная астма у детей. Стратегия лечения и профилактика». 2017:159. [National program «Bronchial asthma in children. Treatment strategy and prevention». 2017: 159. (In Russ.)]
4. Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma (GINA). WHO, updated 2019.
5. Визель А.А., Алексеев А.П., Шмелев Е.И., Яушев М.Ф., Визель И.Ю. Бронхообструктивный синдром у больных туберкулезом легких: аналитический обзор литературы. Практическая пульмонология. 2018; 1: 33—42. [Vizel A.A., Alekseev A.P., Shmelev E.I., Yaushev M.F., Vizel I.Yu. Broncho-obstructive syndrome in patients with pulmonary tuberculosis: an analytical review of the literature. Prakticheskaya Pul'monologiya=Practical pulmonology. 2018; 1: 33—42. (In Russ.)]
6. Шмелев Е.И., Куклина Г.М. Коррекция бронхообструктивного синдрома у больных туберкулезом легких. Медицинский совет. 2013; 3: 20—24. [Shmelev E.I., Kuklina G.M. Correction of broncho-obstructive syndrome in patients with pulmonary tuberculosis. Meditsinskiy Sovet=Medical Аdvice. 2013; 3: 20—24. (In Russ.)]
7. Салова А.Л., Челнокова О.Г., Мозжухина Л.И. Дети с повторными эпизодами крупа — группа высокого риска по туберкулезу. Вестник Центрального научно-исследовательского института туберкулеза. 2019; 3: 40—48. [Salova A. L., Chelnokova O. G., Mozzhukhina L. I. Children with repeated episodes of croup are a high-risk group for tuberculosis. Vestnik Tsentral'nogo Nauchno-issledovatel'skogo Instituta Tuberkuleza=Bulletin of the Central Research Institute of Tuberculosis. 2019; 3: 40—48. (In Russ.)]
Review
For citations:
Salova A.L., Chelnokova O.G., Mozzhukhina L.I., Kogut T.A. Bronchial obstructive syndrome in primary infection with Mycobacterium tuberculosis in children. CHILDREN INFECTIONS. 2020;19(4):34-37. (In Russ.) https://doi.org/10.22627/2072-8107-2020-19-4-34-37
Views:
983
Email this article 