Preview

The modern view of congenital cytomegalovirus infection: clinical observations

https://doi.org/10.22627/2072-8107-2020-19-4-58-63

Abstract

Тhis work is a continuation of the literature review «The modern view of congenital cytomegalovirus infection» and is devoted to the clinical cases.
Particular attention is paid to the severity of congenital cytomegalovirus infection (CCMVI), as well as the its clinical variability, including developmental anomalies. The variety of clinical forms requires a wide range of examinations to identify all this infection manifestations in a newborn child and children in the first months of life, as well as the doctors alertness regarding the timely diagnosis of intrauterine infections based on the existing clinical features.
The presented cases demonstrate the CCMVI clinical manifestations: the «classical» generalized manifest form, with a specific clinical, laboratory and instrumental findings, the severe generalized CCMVI with kidney congenital malformation and postnatal development of congenital cataract.

About the Authors

N. V. Kholodnova
G.N. Speransky City Children’s Hospital N 9
Russian Federation

Natalia Kholodnova, neonatologist

Moscow



L. N. Mazankova
Russian Medical Academy of Post-Graduate Education
Russian Federation

MD

Moscow



A. A. Volter
Pirogov Russian National Research Medical University
Russian Federation
Moscow


I. E. Turina
I.M. Sechenov First Moscow State Medical University of the Russian Federation (Sechenov University)
Russian Federation

PhD

Moscow



A. L. Rossina
G.N. Speransky City Children’s Hospital N 9; Pirogov Russian National Research Medical University
Russian Federation

PhD

Moscow



O. Yu. Brunova
G.N. Speransky City Children’s Hospital N 9
Russian Federation
Moscow


L. M. Makarova
G.N. Speransky City Children’s Hospital N 9
Russian Federation
Moscow


References

1. Lanzieri T.M., Dollard S.C., Bialek S.R., Grosse S.D. Systematic review of the birth prevalence of congenital cytomegalovirus infection in developing countries. Int J Infect Dis. 2014; 22:44—48 https://doi.org/10.1016/j.ijid.2013.12.010

2. Leung J., Cannon M.J., Grosse S.D., Bialek S.R. Laboratory testing and diagnostic coding for cytomegalovirus among privately insured infants in the United States: a retrospective study using administrative claims data. BMC Pediatrics. 2013; 13:90. https://doi.org/0.1186/1471-2431-13-90

3. Koyano S., Inoue N., Oka A., et al. Screening for congenital cytomegalovirus infection using newborn urine samples collected on filter paper: feasibility and outcomes from a multicentre study. BMJ Open. 2011; 1:e000118. doi: 10.1136/bmjopen-2011-000118

4. Врожденная цитомегаловирусная инфекция: Клинические рекомендации. М.: РАСПМ, 2016. [Congenital cytomegalovirus infection: Clinical guidlines. М.: RASPM, 2016. (In Russ.)]

5. Орехов К.В., Голубева М.В., Барычева Л.Ю. Врожденная цитомегаловирусная инфекция. Детские инфекции. 2004; 1:49—55. [Orehov K.V., Golubeva M.V., Baryicheva L.Yu. Congenital cytomegalovirus infection. Detskie Infektsii=Children's infections. 2004; 1: 49—55. (In Russ.)]

6. Кочкина С.С., Ситникова Е.П. Клинические «маски» врожденной цитомегаловирусной инфекции у детей. Вестн. соврем. клин. медицины. 2013; 6(1):31—33. [Kochkina S.S., Sitnikova E.P. Current clinical features cytomegalovirus infection. Vestn. Sovrem. Klin. Mediciny. 2013; 6(1):31—33. (in Russ.)]


Review

For citations:


Kholodnova N.V., Mazankova L.N., Volter A.A., Turina I.E., Rossina A.L., Brunova O.Yu., Makarova L.M. The modern view of congenital cytomegalovirus infection: clinical observations. CHILDREN INFECTIONS. 2020;19(4):58-63. (In Russ.) https://doi.org/10.22627/2072-8107-2020-19-4-58-63

Views: 828


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2072-8107 (Print)
ISSN 2618-8139 (Online)