Characteristics of measles in children during the rise in incidence in 2019
https://doi.org/10.22627/2072-8107-2022-21-4-27-31
Abstract
In Moscow, as in Russia, in 2019 there was an increase in the incidence of measles in recent years.
Purpose: to analyze the course of measles in children hospitalized in 2019 during the period of rising incidence.
Materials and methods: a retrospective analysis and statistical processing of 30 case histories of children hospitalized with measles in the infectious diseases department of the Children's City Clinical Hospital № 9 named after G.N. Speransky in 2019.
Results: More than half of the patients were under the age of 3 years (53%). In 90% of cases, the sick were not vaccinated, in 73% – due to the refusal of their parents. Only 23% of patients had measles contact, mostly familial. Measles in hospitalized children proceeds typically, in 83.3% of cases in a moderate form, with characteristic pathognomonic symptoms: in 83.3% of patients, Belsky-Filatov-Koplik spots are detected, on average, on the 4.4 ± 0.8 day of illness, spotted – papular rash on the face with staged distribution and subsequent staged pigmentation in all patients. Complications develop in 66.7% of cases, more often pneumonia (36.7%) and obstructive bronchitis (20%), which in 16.7% of cases cause the severity of the course and lead to the development of emergency syndromes and conditions (respiratory failure, obstructive syndrome).
Conclusions. Failure to vaccinate against measles contributes to morbidity with possible complications.
About the Authors
O. V. MolochkovaRussian Federation
Molochkova О.
Moscow
O. B. Kovalev
Russian Federation
Kovalev О.
Moscow
M. A. Kosyreva
Russian Federation
Kosyreva М.
Moscow
N. O. Ilyina
Russian Federation
Ilyina N.
Moscow
O. V. Shamsheva
Russian Federation
Shamsheva О.
Moscow
E. N. Getmanova
Russian Federation
Getmanova Е.
Moscow
A. A. Korsunsky
Russian Federation
Korsunskiy А.
Moscow
E. V. Galeeva
Russian Federation
Galeeva Е.
Moscow
A. A. Guzhavina
Russian Federation
Guzhavina А.
Moscow
References
1. Tsvirkun O.V., Tikhonova N.T., Yushchenko G.V., Gerasimova A.G. Epidemic process of measles in different periods of its vaccination. Epidemiologiya i Vaktsinoprofilaktika = Epidemiology and Vaccinal Prevention. 2015; 14(2):80—87. (In Russ.)
2. Yunasova T.N., Gorenkov D.V, Rukavishnikov A.V., Movsesyants A.A, Merkulov V.A. Analysis of measles incidence in Russia and problems of measles prevention at the elimination stage. BIOpreparaty. Profilaktika, Diagnostika, Lechenie = BIOpreparations. Prevention, Diagnosis, Treatment. 2019; 19(3):154—160. (In Russ.)
3. Tsvirkun O.V., Gerasimova A.G., Tikhonova N.T., Ezhlova E.B., Melnikova A.A., Dubovitskaya E.L., Orlova O.S., Basov A.A., Frolov R.A. Measles Cases by Age Group during the Elimination of Infection. Epidemiologiya i Vaktsinoprofilaktika = Epidemiology and Vaccinal Prevention. 2017; 16(3):18—25. (In Russ.)
4. http://www.euro.who.int/ru/media-centre/sections/press-releases/2019/measles-in-europe-record-number-of-both-sick-and-immunized. Kopengagen. 7 fevralya 2019.
5. Misin A., R.-M. Antonello, S. Di Bella, G. Campisciano, N. Zanotta, D.-R. Giacobbe, M. Comar, R. Luzzati. Measles: An Overview of a Re-Emerging Disease in Children and Immunocompromised Patients. Microorganisms. 2020 Feb 18; 8(2):276. doi: 10.3390/microorganisms8020276
6. Artemova I.V., Kulichenko T.V. Measles epidemic. Is the threat real? Voprosy Sovremennoy Pediatrii = Questions of Modern Pediatrics. 2017; 16(5):358—361. (In Russ.)
7. On the state of sanitary and epidemiological well-being of the population in the Russian Federation in 2021: State report. Moscow: Federal Service for Supervision of Consumer Rights Protection and Human Welfare, 2022:340. (In Russ.)
8. Kharchenko G.A., Kimirilova O.G. Clinical and epidemiological features of the Measles in children of the Astrakhan region. Detskie Infektsi = Children's infections. 2019; 18(3):31—36. (In Russ.)
9. Timchenko V.N., Chernova T.M., Bulina O.V., Pavlova E.B., Nazarova A.N., Leonicheva O.A., Timofeeva E.V. Measles in infants. Detskie Infektsi = Children's infections. 2015; 14(2):52—58. (In Russ.)
10. Timchenko V.N., E.B. Pavlova, O.O. Fedyuchek, R.A. Ivanova, N.V. Pavlova, S.I. Minchenko. Measles in children in modern conditions. Pediatricheskaya Farmakologiya = Pediatric Pharmacology. 2012; 9(6):12—15. (In Russ.)
11. Mazankova L.N., N.M. Belyaeva, S.G. Gorbunov, L.F. Nesterina. Measles in children and adults at the stage of elimination: a study guide. M.: MEDpress-inform, 2018:72. (In Russ.)
12. Molochkova O.V., Kovalev O.B., Shamsheva O.V., Ilyina N.O., Kosyreva M.A., Brunova O.Yu., Mayatsky A.A., Korsunsky A.A., Kashchenko O.A., Galeeva E.V. Bronchopulmonary complications in children with measles (family case). Detskie Infektsii = Children's Infections. 2019; 18(2):42—48. (In Russ.)
Review
For citations:
Molochkova O.V., Kovalev O.B., Kosyreva M.A., Ilyina N.O., Shamsheva O.V., Getmanova E.N., Korsunsky A.A., Galeeva E.V., Guzhavina A.A. Characteristics of measles in children during the rise in incidence in 2019. CHILDREN INFECTIONS. 2022;21(4):27-31. (In Russ.) https://doi.org/10.22627/2072-8107-2022-21-4-27-31