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ACUTE RESPIRATORY SYNCYTIAL VIRUS INFECTION IN CHILDREN IN THE AGE ASPECT

https://doi.org/10.22627/2072-8107-2013-12-4-19-23

Abstract

The clinical features of laboratory-confirmed acute respiratory syncytial virus infection (ARSVI) are described in 221 children of the age from 1 month to 5 years. Febrile fever has been recorded in 76% of patients with ARSVI, and significantly more often in children in the second year of life (92%), but the difference in the temerature or duration has not been found. 98% of children have had symptoms of the lower respiratory tract lesions. The most common ARSVI manifestations in the patients of the first year of life were obstructive diseases of the lower respiratory tract (obstructive bronchitis in 53% and bronchiolitis in 11% of children), in the patients of the second year of life — pneumonia (28%, p < 0,05) and catarrhal otitis (26%; p < 0,05). Bronchial obstruction syndrome in children of the first year of life was characterized by the significantly higher frequency (73%) and the maximal duration (9,7 ± 1,08 days). The largest number of cases of the severe respiratory failure has been recorded among patients of the second year of life (3 degree of respiratory failure in 22% of patients, p < 0,05).

About the Authors

V. B. Rovny
North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg
Russian Federation


O. M. Ibragimova
Research Institute of Children’s Infections, Saint-Petersburg
Russian Federation


Yu. V. Lobzin
North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg; Research Institute of Children’s Infections, Saint-Petersburg
Russian Federation


I. V. Babachenko
Research Institute of Children’s Infections, Saint-Petersburg
Russian Federation


References

1. Garofalo R.P. Respiratory syncytial virus infection: mechanisms of redox control and novel therapeutic opportunities / R.P. Garofalo, D. Kolli, A. Casola // Antioxidants and Redox Signaling. — 2013. — V. 18. — № 2. — Р. 186—217.

2. DeVincenzo J.P. Factors predicting childhood respiratory syncytial virus severity // The Pediatric Infection Disease Journal. — 2005. — V. 24. — № 11. — Р. 177—184.

3. Persistent recurring wheezing in the fifth year of life after laboratoryconfirmed, medically attended respiratory syncytial virus infection in infancy / Gabriel J. Escobar et al. // BMC Pediatrics. — 2013. — V. 13. — № 97. — Р. 1—9.

4. The natural history of respiratory syncytial virus in a birth cohort: the influence of age and previous infection on reinfection and disease / E. O. Ohuma et al. // American Journal of Epidemiology. — 2012. — V. 176. — № 9. — Р. 794—802.

5. The use of humanized monoclonal antibodies for the prevention of respiratory syncytial virus infection / M. Lanari et al. // Clinical and Developmental Immunology. — 2013. — V. 2013. — P. 1—9.

6. Popow-Kraupp T. Diagnosis of respiratory syncytial virus infection / T. Popow-Kraupp, J.H. Aberle // The Open Microbiology Journal. — 2011. — V. 5. — P. 128—134.

7. Openshaw P. Emerging drugs for respiratory syncytial virus infection / P. Openshaw, W. Olszewska // Expert Opin Emerg Drugs. — 2009. — V. 14. — № 2. — Р. 207—217.

8. Лещинская Н.П. Респираторно-синцитиальная вирусная инфекция / Н.П. Лещинская, Л.Е. Камфорин. — М.: Медицина и здравоохранение, 1986. — 77 с.

9. Дифференциальная диагностика инфекционных болезней / Т.М. Зубик и др. — Л.: Медицина, 1991. — 336 с.

10. Клинико-эпидемиологические особенности респираторно-синцитиальной инфекции у детей разного возраста / В.Б. Ровный и др. // Журнал инфектологии. — 2013. — Т. 5, № 2. — С. 76—81.


Review

For citations:


Rovny V.B., Ibragimova O.M., Lobzin Yu.V., Babachenko I.V. ACUTE RESPIRATORY SYNCYTIAL VIRUS INFECTION IN CHILDREN IN THE AGE ASPECT. CHILDREN INFECTIONS. 2013;12(4):19-23. (In Russ.) https://doi.org/10.22627/2072-8107-2013-12-4-19-23

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ISSN 2072-8107 (Print)
ISSN 2618-8139 (Online)