Combined Therapy at Persistent Herpes Virus Infection in Sickly Children
https://doi.org/10.22627/2072-8107-2012-11-0-31-36
Abstract
We examined 40 sickly children with recurrent croup (RC — 28) and bronchial obstruction (ROB — 8), (RC + ROB — 4) aged from 18 months till 14 years. We found that high frequency of persistent herpes viruses usually occurs as associations with CMV, EBV and human herpes virus 6 type. We substantiated anti viral and immune corrective therapy in two schemes compared in efficacy: the 1st group was administered monotherapy with Viferon, and the 2nd group received combined therapy Viferon + Arbidol in doses according to the age during three months. We received a more expressed clinical immunologic effect from the therapy with decreased antigenic load and frequency of recurrence of RC and ROB with Viferon application in suppositories in combination with Arbidol per orally in the intermittent scheme during three months.
About the Authors
F. S. Kharlamova
Russian National Research Medical University named after N.I. Pirogov, Morozov Children's City Clinical Hospital, Moscow
Russian Federation
Russian Federation
V. F. Uchaykin
Russian National Research Medical University named after N.I. Pirogov, Morozov Children's City Clinical Hospital, Moscow
Russian Federation
Russian Federation
T. P. Legkova
Russian National Research Medical University named after N.I. Pirogov, Morozov Children's City Clinical Hospital, Moscow
Russian Federation
Russian Federation
L. I. Feldfiks
Russian National Research Medical University named after N.I. Pirogov, Morozov Children's City Clinical Hospital, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Kharlamova F.S., Uchaykin V.F., Legkova T.P., Feldfiks L.I. Combined Therapy at Persistent Herpes Virus Infection in Sickly Children. CHILDREN INFECTIONS. 2012;11:31-36. (In Russ.) https://doi.org/10.22627/2072-8107-2012-11-0-31-36
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