HERPESVIRUS INFECTIONS IN CHILDREN WITH RECURRENT RESPIRATORY DISEASES
https://doi.org/10.22627/2072-8107-2018-17-2-17-21
Abstract
The article presents the role of herpesviral infections caused by the herpes simplex virus (HSV), the Epstein-Barr virus (EBV), cytomegalovirus (CMV) and human herpesvirus type 6 (HHV-6) in 36 children with recurrent respiratory tract diseases at the age from 1 to 18 years. Blood sera and blood cells were studied using ELISA, Indirect reaction of immunofluorescence and Rapid culture method.
It was found that all 36 children (100%) were infected with HSV, EBV, CMV and HHV-6. Most often — in 19 children (52.8%) the signs of active HHV-6 were revealed. In the same number of children surveyed, it was possible to identify active EBVI (16 children — 44.4%) and CMVI (16—44.4%). Active HSVI was diagnosed in 13 children (36.1%). Herpes virus infections were most often detected in the age group of children from 3 to 7 years of age.
All children with recurrent respiratory diseases should be examined for herpesvirus infections.
About the Authors
M. Yu. LysenkovaRussian Federation
Maria Lysenkova, Ph.D., senior researcher, Laboratory of Epidemiology of opportunistic infections
Moscow
N. V. Karazhas
Russian Federation
Natalia Karazhas, MD, Professor, Head of the Laboratory of Epidemiology of Opportunistic Infections
Moscow
E. V. Melekhina
Russian Federation
Elena Melekhina, MD, Associate Professor, Senior Research Associate, Clinical Department of Infectious Diseases
Moscow
T. N. Rybalkina
Russian Federation
Tatyana Rybalkina, Ph.D., senior researcher, epidemiology of opportunistic infections laboratory
Moscow
P. A. Veselovsky
Russian Federation
Pavel Veselovsky, junior researcher at the Laboratory of Epidemiology of Opportunistic Infections
Moscow
E. M. Burmistrov
Russian Federation
Yegor Burmistrov, junior researcher of the laboratory of epidemiology of opportunistic infections
Moscow
R. E. Boshyan
Russian Federation
Roman Boshyan, Ph.D., Research Associate in the Laboratory of Epidemiology of Opportunistic Infections
Moscow
A. D. Muzyka
Russian Federation
Anna Musikа, Junior Researcher, Clinical Department of Infectious Diseases
Moscow
A. V. Gorelov
Russian Federation
Alexander Gorelov, Corresponding Member of RAS, MD, Professor; Head of Clinical Department of Infectious Diseases
Moscow
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Review
For citations:
Lysenkova M.Yu., Karazhas N.V., Melekhina E.V., Rybalkina T.N., Veselovsky P.A., Burmistrov E.M., Boshyan R.E., Muzyka A.D., Gorelov A.V. HERPESVIRUS INFECTIONS IN CHILDREN WITH RECURRENT RESPIRATORY DISEASES. CHILDREN INFECTIONS. 2018;17(2):17-21. (In Russ.) https://doi.org/10.22627/2072-8107-2018-17-2-17-21