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CHILDREN INFECTIONS

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HERPESVIRUS INFECTIONS IN CHILDREN WITH RECURRENT RESPIRATORY DISEASES

https://doi.org/10.22627/2072-8107-2018-17-2-17-21

Abstract

The article presents the role of herpesviral infections caused by the herpes simplex virus (HSV), the Epstein-Barr virus (EBV), cytomegalovirus (CMV) and human herpesvirus type 6 (HHV-6) in 36 children with recurrent respiratory tract diseases at the age from 1 to 18 years. Blood sera and blood cells were studied using ELISA, Indirect reaction of immunofluorescence and Rapid culture method.

It was found that all 36 children (100%) were infected with HSV, EBV, CMV and HHV-6. Most often — in 19 children (52.8%) the signs of active HHV-6 were revealed. In the same number of children surveyed, it was possible to identify active EBVI (16 children — 44.4%) and CMVI (16—44.4%). Active HSVI was diagnosed in 13 children (36.1%). Herpes virus infections were most often detected in the age group of children from 3 to 7 years of age.

All children with recurrent respiratory diseases should be examined for herpesvirus infections.

About the Authors

M. Yu. Lysenkova
National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamalei of the Ministry of Health of Russia
Russian Federation

Maria Lysenkova, Ph.D., senior researcher, Laboratory of Epidemiology of opportunistic infections 

Moscow



N. V. Karazhas
National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamalei of the Ministry of Health of Russia
Russian Federation

Natalia Karazhas, MD, Professor, Head of the Laboratory of Epidemiology of Opportunistic Infections

Moscow



E. V. Melekhina
Central Scientific Research Institute of Epidemiology of the Rospotrebnadzor
Russian Federation

Elena Melekhina, MD, Associate Professor, Senior Research Associate, Clinical Department of Infectious Diseases

Moscow



T. N. Rybalkina
National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamalei of the Ministry of Health of Russia
Russian Federation

Tatyana Rybalkina, Ph.D., senior researcher, epidemiology of opportunistic infections laboratory 

Moscow



P. A. Veselovsky
National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamalei of the Ministry of Health of Russia
Russian Federation

Pavel Veselovsky, junior researcher at the Laboratory of Epidemiology of Opportunistic Infections 

Moscow



E. M. Burmistrov
National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamalei of the Ministry of Health of Russia
Russian Federation

Yegor Burmistrov, junior researcher of the laboratory of epidemiology of opportunistic infections 

Moscow



R. E. Boshyan
National Research Center for Epidemiology and Microbiology named after Honorary Academician N.F. Gamalei of the Ministry of Health of Russia; First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of Russia
Russian Federation

Roman Boshyan, Ph.D., Research Associate in the Laboratory of Epidemiology of Opportunistic Infections 

Moscow



A. D. Muzyka
Central Scientific Research Institute of Epidemiology of the Rospotrebnadzor
Russian Federation

Anna Musikа, Junior Researcher, Clinical Department of Infectious Diseases 

Moscow



A. V. Gorelov
Central Scientific Research Institute of Epidemiology of the Rospotrebnadzor
Russian Federation

Alexander Gorelov, Corresponding Member of RAS, MD, Professor; Head of Clinical Department of Infectious Diseases

Moscow



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For citations:


Lysenkova M.Yu., Karazhas N.V., Melekhina E.V., Rybalkina T.N., Veselovsky P.A., Burmistrov E.M., Boshyan R.E., Muzyka A.D., Gorelov A.V. HERPESVIRUS INFECTIONS IN CHILDREN WITH RECURRENT RESPIRATORY DISEASES. CHILDREN INFECTIONS. 2018;17(2):17-21. (In Russ.) https://doi.org/10.22627/2072-8107-2018-17-2-17-21

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ISSN 2072-8107 (Print)
ISSN 2618-8139 (Online)