OPTIMIZATION OF DIAGNOSIS OF CYTOMEGALOVIRUS INFECTION IN YOUNG CHILDREN
https://doi.org/10.22627/2072-8107-2018-17-3-51-56
Abstract
The results of a laboratory examination of 520 children aged 1—3 years are presented. The examination was conducted to determine the DNA of cytomegalovirus in children with acute cytomegalovirus infection in various biological media by polymerase chain reaction. The differences in the virus shedding into the blood, saliva, and urine are established: the median of the viral load for saliva is 4.9 lg copies of DNA/ml, the blood 3.4 lg copies of DNA/ml, urine — 3.85 lg copies of DNA/ml. The cut of extreme values of the viral load are determined with the help of mathematical modeling which determine the clinical probability of developing acute CMV infection which allows for more accurate and timely assignment of etiotropic therapy.
About the Authors
A. V. Permyakova
Perm Medical State University named after E.A. Wagner
Russian Federation
Perm.
Russian Federation
Perm.
N. S. Pospelova
Perm Medical State University named after E.A. Wagner
Russian Federation
Perm.
Russian Federation
Perm.
I. I. Lvova
Perm Medical State University named after E.A. Wagner
Russian Federation
Perm.
Russian Federation
Perm.
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Review
For citations:
Permyakova A.V., Pospelova N.S., Lvova I.I. OPTIMIZATION OF DIAGNOSIS OF CYTOMEGALOVIRUS INFECTION IN YOUNG CHILDREN. CHILDREN INFECTIONS. 2018;17(3):51-56. (In Russ.) https://doi.org/10.22627/2072-8107-2018-17-3-51-56
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